Regulation of alkaline phosphatase gene expression in human hepatoma cells by bile acids

Journal of Gastroenterology and Hepatology (Australia)

Volumn 13, Issue 6, 1998, Pages 643-650

  Khan, Khaleque Newaz ^a   Tsutsumi, Takuya ^b   Nakata, Keisuke ^a   Nakao, Kazuhiko ^a   Kato, Yuji ^a   Nagataki, Shigenobu ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b OITA PREFECTURAL HOSPITAL   (Japan)

Author keywords

Alkaline phosphatase; Chenodeoxycholic acid; Cholic acid; Hepatoma cells; Northern blotting; Ursodeoxycholic acid

Indexed keywords

ALKALINE PHOSPHATASE; BILE ACID; CHENODEOXYCHOLIC ACID; CHOLIC ACID; URSODEOXYCHOLIC ACID;

ARTICLE; BILE SECRETION; CELL ACTIVITY; CELL CULTURE; ENZYMATIC ASSAY; ENZYME ACTIVITY; GENE CONTROL; GENE EXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; NORTHERN BLOTTING; PRIORITY JOURNAL; RNA TRANSCRIPTION;

EID: 0031754302     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.1998.tb00703.x     Document Type: Article

References (36)

1. McComb RB, Posen S. Alkaline phosphatases. New York: Plenum Publishing Corporation, 1979.
2. Harris H. The Harvey Lectures: Series 76. Orlando, FL: Academy Press, 1982.
3. Goldstein DJ, Rogers C, Harris H. A search for trace expression of placental-like alkaline phosphatase in nonmalignant human tissues: Demonstration of its occurance in lung, cervix, testis and thymus. Clin. Chem. Acta 1982; 125: 63-75.
4. Robinson R. Characterization of biochemical properties of alkaline phosphatase. Biochem. J. 1923; 17: 286-93.
5. Wuthier RE, Register TC. Alkaline phosphatase and bone mineralization. In: Butler WT (ed.). Chemistry and biology of mineralized tissues. Birmingham AL: EBSCO Media, 1985; 113-24.
6. Kiledjian M, Kadesch T. Analysis of the human liver/ bone/kidney alkaline phosphatase promoter in vivo and in vitro. Nucleic Acids Res. 1990; 18: 957-61.
7. Kiledjian M, Kadesch T. Post transcriptional regulation of the human liver/bone/kidney alkaline phosphatase gene. J. Biol. Chem. 1991; 266: 4207-13.
8. Kaplan MM, Righetti A. Induction of rat liver alkaline phosphatase: The mechanism of the serum elevation in bile duct obstruction. J. Clin. Invest. 1970; 49: 508-16.
9. Hatoff DE, Hardison WGM. Induced synthesis of alkaline phosphatase by bile acids in rat liver cell culture. Gastroenterology 1979; 77: 1062-7.
10. Hatoff DE, Hardison WGM. Bile acid dependent secretion of alkaline phosphatase in rat bile. Hepatology 1982; 2: 433-9.
11. Kaplan MM, Ohkubo A, Quaroni EG, Sze-Tu D. Increased synthesis of rat liver alkaline phosphatase by bile duct ligation. Hepatalogy 1983; 3: 368-76.
12. Komoda T, Kumegawa M, Yajima T, Tamura T, Alpers DH. Induction of rat hepatic and intestinal alkaline phosphatase activity produced by bile from bile duct-ligated animals. Am. J. Physiol. 1984; 246: 393-400.
13. Weiss MJ, Ray K, Henthorn PS, Lamb B, Kadesch T, Harris H. Structure of the human liver/bone/kidney alkaline phosphatase gene. J. Biol. Chem. 1988; 263: 12002-10.
14. Schlaeger R. The mechanism of the increase in the activity of liver alkaline phosphatase in experimental cholestasis: Measurements of an increased enzyme concentration by immunochemical titration. J. Clin. Chem. Clin. Biochem. 1975; 13: 277-81.
15. Righetti ABB, Kaplan MM. Effects of actinomycin D on rat liver alkaline phosphatase. Proc. Soc. Exp. Biol. Med. 1971; 136: 491-5.
16. Greim H, Trulzsch D, Roboz J. Mechanisms of cholestasis. 5. Bile acids in normal rat livers and in those after bile duct ligation. Gastroenterology 1972; 63: 837-45.
17. Moss DW. Perspectives in alkaline phosphatase research. Clin. Chem. 1992; 38: 2486-92.
18. Heuman DM, Hernandez CR, Hylemon PB, Kubaska WM, Hartman C, Vlahcevic ZR. Regulation of bile acid synthesis. I. Effects of conjugated ursodeoxycholate and cholate on bile acid synthesis in chronic bile fistula rat. Hepatology 1988; 8: 358-65.
19. Heuman DM, Vlahcevic ZR, Bailey ML, Hylemon PB. Regulation of bile acid synthesis. II. Effects of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat. Hepatology 1988; 8: 892-7.
20. Vlahcevic ZR, Heuman DM, Hylemon PB. Regulation of bile acid synthesis. Hepatology 1991; 13: 590-600.
21. Podda M, Ghezzi C, Battezzati PM, Crosignani A, Zuin M, Roda A. Effects of ursodeoxycholic acid and taurine on serum liver enzymes and bile acids in chronic hepatitis. Gastroenterology 1990; 98: 1044-50.
22. Yoshikawa M, Tsuji T, Matsumura K et al. Immunomodulatory effects of ursodeoxycholic acid on immune responses. Hepatology 1992; 16: 358-64.
23. Seetharam S, Sussman NL, Komoda T, Alpers DH. The mechanism of elevated alkaline phosphatase activity after bile duct ligation in the rat. Hepatology 1986; 6: 374-80.
24. Terao M, Mintz B. Cloning and characterization of a cDNA coding for mouse placental alkaline phosphatase. Proc. Natl Acad. Sci. USA 1987; 84: 7051-5.
25. Weiss MJ, Henthorn PS, Lafferty MA, Slaughter C, Raducha M, Harris H. Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase. Proc. Natl Acad. Sci. USA 1986; 83: 7182-6.
26. Nakabayashi H, Taketa K, Yamane T, Miyazaki M, Miyano K, Sato J. Phenotypical stability of a human hepatoma cell line, HuH-7, in long term culture with chemically defined medium. Gann 1984; 75: 151-8.
27. Bowers GN Jr, McComb RB. A continuous spectrophotometric method for measuring the activity of serum alkaline phosphatase. Clin. Chem. 1966; 12: 70.
28. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 1976; 72: 248-54.
29. Matsuura S, Kishi F, Kajii T. Characterization of a 5′-flanking region of the human liver/bone/kidney alkaline phosphatase gene:Two kinds of mRNA from a single gene. Biochem. Biophys. Res. Commun. 1990; 168: 993-1000.
30. Terao M, Studer M, Gianni M, Garattini E. Isolation and characterization of the mouse liver/bone/kidney-type alkaline phosphatase gene. Biochem. J. 1990; 268: 641-8.
31. Toh Y, Yamamoto M, Endo H, Misumi Y, Ikehara Y. Isolation and characterization of a rat liver alkaline phosphatase gene, a single gene with two promoters. Eur. J. Biochem. 1989; 182: 231-7.
32. Ohiwa T, Katagiri K, Hoshino M, Hayakawa T, Nakai T. Tauroursodeoxycholate and tauro-b-muricholate exert cytoprotection by reducing intrahepatocyte taurochenodeoxycholate content. Hepatology 1993; 17: 470-6.
33. Kullak-Ublick GA, Beuers U, Paumgartner G. Molecular and functional characterization of bile acid transport in human hepatoblastoma HepG2 cells. Hepatology 1996; 23: 1053-60.
34. Tokiwa T, Endo A, Sato J. Alkaline phosphatase expression in human cell lines derived from primary hepatomas. Expl. Cell Biol. 1989; 57: 324-9.
35. Cronholm T, Sjovall J. Bile acids in portal blood of rats fed different diets and cholestyramine. Bile acids and steroids 189. Eur. J. Biochem. 1967; 2: 375-83.
36. Okishio T, Nair PP. Studies on bile acids. Some observations on the intracellular localization of major bile acids in rat liver. Biochemistry 1966; 5: 3662-8.