In vivo evaluation of a drug-inducible vector system for the combined geneand chemotherapy of cancer

Advances in Experimental Medicine and Biology

Volumn 451, Issue , 1998, Pages 139-144

  Walther, W ^a   Stein, U ^a   Fichtner, I ^a   Naundorf, H ^a   Alexander, M ^b   Shoemaker, R H ^b   Schlag, P M ^c  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b NATIONAL CANCER INSTITUTE   (United States)

^c Section of Pathology   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CELL STRAIN MCF 7; EXPRESSION VECTOR; GENE THERAPY; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL;

ANIMALS; BREAST NEOPLASMS; COLONIC NEOPLASMS; COMBINED MODALITY THERAPY; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; FEMALE; GENETIC VECTORS; HUMANS; MICE; MICE, NUDE; MOLONEY MURINE LEUKEMIA VIRUS; PROMOTER REGIONS (GENETICS); TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031753501     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5357-1_22     Document Type: Article

References (7)

1. W. Walther, U. Stein, 1996; Targeted vectors for gene therapy of cancer and retroviral infections. Mol. Biotechnol. 6, 267-286.
2. K. Kohno, S.-I. Sato, H. Takano, K.-I. Matsuo, M. Kuwano, 1989; The direct activation of human multidrug resistance gene(MDR1) by anticancer agents. Biochem. Biophys. Res. Comm. 165, 1415-1421.
3. U. Stein, W. Walther, R. H. Shoemaker, 1996; Vincristine induction of mutant and wild type human multidrug-resistance promoters is cell-type-specific and dose-dependent. J. Cancer Res. Clin. Oncol. 122, 275-282.
4. U. Stein, W. Walther, R. H. Shoemaker, 1996; Modulation of mdrl expression by cytokines in human colon carcinoma cells: an approach for reversal of multidrug resistance. Br. J. Cancer 74, 1384-1391.
5. U. Stein, W. Walther, R. H. Shoemaker, 1996; Reversal of multidrug resistance by transduction of cytokine genes into human colon carcinoma cells. J. Natl. Cancer Inst. 88, 1383-1392.
6. W. Walther, J. Wendt, U. Stein, 1997; Employment of the mdrl promoter for the chemotherapy-inducible expression of therapeutic genes in cancer gene therapy. Gene Ther. 4, 544-552.
7. G. Chu, H. Hayakawa, P. Berg, 1987; Electroporation for the efficient transfection of mammalian cells with DNA. Nucleic. Acids Res. 15, 1311-1326.