Application of capillary electrophoresis, liquid chromatography, electrospray-mass spectrometry and matrix-assisted laser desorption/ionization - Time of flight - Mass spectrometry to the characterization of recombinant human erythropoietin

Electrophoresis

Volumn 19, Issue 13, 1998, Pages 2348-2355

  Zhou, Guo Hua ^a   Luo, Guo An ^a   Zhou, Yong ^b   Zhou, Ke Yu ^c   Zhang, Xiao Dano ^b   Huang, Le Qun ^a  

^a TSINGHUA UNIVERSITY   (China)

^b Nanjing Military Medical Institute   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Electrospray mass spectrometry; High performance capillary electrophoresis; High performance liquid chromatography; Ionization; Mass spectrometry; Matrix assisted laser desorption; Recombinant human erythropoietin; Time of flight

Indexed keywords

ACETYLATION; CAPILLARY ELECTROPHORESIS; DESORPTION; ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INDUCTIVELY COUPLED PLASMA; PEPTIDES;

ELECTROSPRAY IONIZATION MASS SPECTROMETRY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN ERYTHROPOIETIN; LC-ESI-MS; MATRIX ASSISTED LASER DESORPTION; MATRIX-ASSISTED LASER DESORPTION/IONIZATION-TIME-OF-FLIGHT MASS SPECTROMETRY; RECOMBINANT HUMAN ERYTHROPOIETIN; TIME-OF FLIGHT;

MASS SPECTROMETRY;

GLYCOPROTEIN; RECOMBINANT ERYTHROPOIETIN; SIALIC ACID;

CAPILLARY ELECTROPHORESIS; CHO CELL; CONFERENCE PAPER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; NONHUMAN; PROTEIN DETERMINATION; PROTEIN POLYMORPHISM;

EID: 0031752254     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.1150191315     Document Type: Conference Paper

References (8)

1. Goldwasser, E., Hung, C. K. H., Ann. N. Y. Acad. Sci. 1968, 149, 49-53.
2. Eschbach, J., Mladenovic, J., Carcia, J., Wahl, P., Adamson, J., J. Clin. Invest. 1984, 74, 434-441.
3. Sasaki, H., Bothner, B., Dell, A., Fukuda, M., J. Biol. Chem. 1987, 262, 12059-12076.
4. Rush, R. S., Derby, P. L., Smith, D. M., Merry, C., Rogers, G., Rohde, M. F., Katta, V., Anal. Chem. 1995, 67, 1442-1452.
5. Goldwasser, E., Kung, C. K.-H., Eliason, J., J. Biol. Chem. 1974, 249, 4202-4206.
6. Higuchi, M., Oh-eda, M., Kuboniwa, H., Tomonoh, K., Shimonaka, Y., Ochi, N., J. Biol. Chem. 1992, 267, 7703-7709.
7. Tran, A. D., Park, S., Lisi, P. J., Huynh, O. T., Ryall, R. R., Lane, P. A., J. Chromatogr. 1991, 542, 459-471.
8. Nimtz, M., Martin, W., Wray, V., Kloppel, K. D., Augustin, J., Conradt, H. S., Eur. J. Biochem. 1993, 213, 39-56.