Growth inhibition of prostate cell lines in vitro by phyto-oestrogens

British Journal of Urology

Volumn 82, Issue 4, 1998, Pages 560-563

  Hempstock, J ^a   Kavanagh, J P ^a   George, N J R ^a  

^a MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Isoflavonoids; Phyto oestrogens; Prevention; Prostate

Indexed keywords

BIOCHANIN A; BROXURIDINE; DAIDZEIN; ESTROGEN; GENISTEIN; GENISTIN; NORDIHYDROGUAIARETIC ACID; PHYTOHORMONE; TETRAZOLIUM;

ARTICLE; CELL LINE; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; DIET; GROWTH INHIBITION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE; PROSTATE CANCER;

CELL DIVISION; CELL LINE; DRUG SYNERGISM; ESTROGENS, NON-STEROIDAL; HUMANS; ISOFLAVONES; MALE; PHYTOESTROGENS; PLANT PREPARATIONS; PROSTATE;

EID: 0031752105     PISSN: 00071331     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-410X.1998.00769.x     Document Type: Article

References (21)

1. Morton MS, Griffiths K. Blacklock N. The preventative role of diet in prostatic disease. Br }Urol 1996: 77: 481-93
2. Adlercreutz H. Diet, breast cancer, and sex hormone metabolism. Ann N Y Acad Sei 1990; 595: 281-90
3. Mills PK, Beeson WL, Phillips RL. Fraser CE. Cohort study of diet, lifestyle, and prostate cancer in Adventist men. Cancer 1989: 64: 598-604
4. Martin PM. Horwitz KB, Ryan US, McGuire WL. Phytoestrogen interaction with estrogen receptors in human breast cancer cells. Endocrinology 1978; 103: 1860-7
5. Kuiper GGJM, Enmark E. Pelto-Huikko M, Nilsson S, Gustafsson J-A. Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Pror Natl Acnd Sei USA 1996: 93: 5925-30
6. Gustafsson J-A. Estrogen receptor -getting in on the action? Nature Med 1997; 3: 493-4
7. Messina M. Barnes S. Setchell KD. Phyto-oestrogens and breast cancer. Lancet 1997: 350: 971-2
8. Mousavi Y, Adlercreutz H. Genistein is an effective stimulator of sex hormone binding globulin production in hepatocarcinoma human liver cancer cells and suppresses proliferation of these cells in culture. Steroids 1993; 58: 301-4
9. Adlercreutz H, Höckerstedt K. Bannwart C et al. Effect of dietary components, including lignans and phytoestrogens. on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG). / Steroid Biochem 1987; 27: 1135-44
10. Adlercreutz H. Bannwart C. Wähälä K et al. Inhibition of human aromatase by mammalian lignans and isoflavonoid phytoestrogens. / Steroid Biochem Molec Biol 1993: 44: 147-53
11. Evans BAJ, Griffiths K. Morton MS. Inhibition of 5a-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. / Endocrinol 1995; 147: 295-302
12. Stephens FO. Phytoestrogens and prostate cancer: possible preventative role. Med }Australia 1997: 167: 138-40 1 3 Bergan R, Kyle E, Nguyen P. Trepel J, Ingui C. Neckers L.
13. Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to beta-1-integrin. Clin Exp Metastasis 1996; 14: 389-98
14. Fotsis T, Pepper M. Adlercreutz H et al Genistein, a dietary derived inhibitor of in vitro angiogenesis. Prof Natl Acad SeiUSA 1993: 90: 2690-4
15. 5 Fotsis T. Pepper M. Adlercreutz H. Hase T. Montesano R. Schweigerer L. Genistein, a dietary ingested isoflavonoid. inhibits cell proliferation and in vitro angiogenesis. Jr 1995: 125: 790S-797S
16. Akiyama T. Ishida J. Nakagawa S et al. Genistein, a spécifie inhibitor of tyrosine-specific protein kinases. J Biol Chetn 1987: 262: 5592-5
17. Ward RS. Lignans. neolignans. and related compounds. Nat Prod Rep 1993: 10: 1-28
18. Peterson G. Barnes S. Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation. Prostate 1993: 22: 335-45
19. Fair WR. Fleshner NE, Heston W. Cancer of the prostate: a nutritional disease? Urology 1997; 50: 840-8
20. Berthon P. Cussenot 0. Hopwood L. Le Duc A. Maitland NJ. Functional expression of SV40 in normal human prostatic epithelial and fibroblastic cells: differentiation pattern of non-tumorigenic cell lines. Int j Oncol 1995; 6: 333-43
21. Food. Nutrition and the Prevention of Cancer; a global perspective. Commissioned by The World Cancer Research Fund and The American Institute for Cancer Research, Published by The American Institute for Cancer Research, Washington 1997.