Insulin and vanadate restore decreased plasma endothelin concentrations and exaggerated vascular responses to normal in the streptozotocin diabetic rat

Diabetologia

Volumn 41, Issue 10, 1998, Pages 1233-1240

  Hopfner, R L ^a   Misurski, D ^a   Wilson, T W ^a   McNeill, J R ^a   Gopalakrishnan, V ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Aorta; Endothelin; Insulin; Streptozotocin diabetic rat; Vanadate

Indexed keywords

ENDOTHELIN; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; GLUCOSE; INSULIN; METHOXAMINE; STREPTOZOCIN; VANADATE SODIUM; VANADIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; SUBCUTANEOUS DRUG ADMINISTRATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; ENDOTHELIN-1; INSULIN; MALE; METHOXAMINE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, SPRAGUE-DAWLEY; VANADATES; VASOCONSTRICTOR AGENTS;

EID: 0031751077     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051057     Document Type: Article

References (41)

1. Tomlinson KC, Gardiner SM, Hebden RA, Bennett T (1992) Functional consequences of streptozotocin induced diabetes mellitus, with particular reference to the cardiovascular system. Pharmacol Rev 44: 103-150
2. Tomita K, Ujiie K, Nakanishi Tet al. (1989) Plasma endothelin levels in patients with acute renal failure. N Eng J Med 321: 1127
3. Lerman A, Edwards BS, Hallet JW, Heublein DM, Sandberg SM, Burnett JC (1991) Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis. N Eng J Med 325: 997-1001
4. Haak T, Jungmann E, Felber A, Hillmann U, Usadel KH (1992) Increased plasma levels of endothelin in diabetic patients with hypertension. Am J Hypertens 5: 161-166
5. Luscher TF, Seo BG, Buhler FR (1993) Potential role of endothelin in hypertension. Hypertension 21: 752-757
6. B receptors on aortic smooth muscle cells of spontaneously hypertensive rats. Am J Physiol 264:C479-C484
7. Pfaffman MA, Ball CR, Darby A, Human R (1982) Insulin reversal of diabetes induced inhibition of vascular contractility in the rat. Am J Physiol 242:H490-H495
8. White RE, Carrier GO (1990) Vascular contraction induced by activation of membrane calcium ion channels is enhanced in streptozotocin diabetes. J Pharmacol Exp Ther 253: 1057-1062
9. 2, but not noradrenaline of aortae from rats with streptozotocin induced diabetes mellitus. Br J Pharmacol 104: 928-932
10. Kiff RJ, Gardiner SM, Compton AM, Bennett T (1991) The effects of endothelin-1 and NG-nitro-L-arginine methyl ester on regional haemodynamics in conscious rats with streptozotocin induced diabetes mellitus. Br J Pharmacol 103: 1321-1326
11. Cameron NE, Cotter MA (1992) Impaired contraction and relaxation in aorta from streptozotocin diabetic rats - role of polyol pathway. Diabetologia 35: 1011-1019
12. Chang KS, Stevens WC (1992) Endothelium dependent increase in vascular sensitivity to phenylephrine in long term streptozotocin diabetic rat aorta. Br J Pharmacol 107: 983-990
13. Tammesild PJ, Hodgson WC, King RG (1992) Increased sensitivity to endothelin-1 in isolated Kreb's-perfused kidneys of streptozotocin diabetic rats. Clin Exp Pharmacol Physiol 19: 261-265
14. Ozcelikay AT, Pekiner C, Ari N, Ozturk Y, Ozuari A, Altan VM (1994) The effect of vanadyl treatment on vascular responsiveness of streptozotocin diabetic rats. Diabetologia 37: 572-578
15. Tada H, Muramatsu I, Nakai T, Kigoshi S, Miyabo S (1994) Effects of chronic diabetes on the responsiveness to endothelin and other agents of rat atria and thoracic aorta. Gen Pharmacol 25: 1221-1228
16. Heygate KM, Davies J, Holmes M, James RF, Thurston H (1996) The effect of insulin treatment and of islet transplantation on the resistance artery function in the STZ-induced diabetic rat. Br J Pharmacol 119: 495-504
17. Makino A, Kamata K (1998) Elevated plasma endothelin-1 level in streptozotocin induced diabetic rats and responsiveness of the mesenteric arterial bed to endothelin-1. Br J Pharmacol 123: 1065-1072
18. Takahashi K, Ghatei MA, Lam HC, O'Hallaran DJ, Bloom SR (1990) Elevated plasma endothelin in patients with diabetes mellitus. Diabetologia 33: 306-310
19. Takeda Y, Miyamori I, Yoneda T, Takeda R (1991) Production of endothelin-1 from the mesenteric arteries of streptozotocin induced diabetic rats. Life Sciences 48: 2553-2556
20. Smulders RA, Stehouwer CD, Olthof CG et al. (1994) Plasma endothelin levels and vascular effects of intravenous L-arginine infusion in subjects with uncomplicated insulin-dependent diabetes mellitus. Clin Sci (Colch) 87: 37-43
21. Malamitsi-Puchner A, Economou E, Katsouyanni K, Karachaliou F, Delis D, Bartsocas CS (1996) Endothelin 1-21 plasma concentrations in children and adolescents with insulin dependent diabetes mellitus. J Pediatr Endocrinol Metab 9(4):463-468
22. Takahashi K, Suda K, Lam HC, Ghatei MA, Bloom SR (1991) Endothelin like immunoreactivity in rat models of diabetes mellitus. J Endocrinol 130: 123-127
23. Oliver FJ, De La Rubia G, Feener EP et al. (1991) Stimulation of endothelin-1 gene expression by insulin in endothelial cells. J Biol Chem 266: 23251-23256
24. Hattori Y, Kasai K, Nakamura T, Emoto T, Shimoda S (1991) Effect of glucose and insulin on immunoreactive endothelin release from cultured porcine aortic endothelial cells. Metabolism 40: 165-169
25. Ferri C, Pittoni V, Piccoli A et al. (1995) Insulin stimulates endothelin-1 secretion from human cultured endothelial cells and modulates its circulating levels in vivo. J Clin Endocrinol Metab 80: 829-835
26. Piatti PM, Monti LD, Conti M et al. (1996) Hypertriglyceridemia and hyperinsulinemia are potent inducers of endothelin release in humans. Diabetes 45: 316-321
27. Frank HJ, Levin ER, Hu RM, Pedram A (1993) Insulin stimulates endothelin binding and action on cultured vascular smooth muscle cells. Endocrinology 133: 1092-1097
28. A receptor expression in rat aortic smooth muscle cells. Diabetes 47: 937-944
29. Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long term complications in insulin dependent diabetes mellitus. N Eng J Med 329: 977-986
30. Brichard SM, Henquin JC (1995) The role of vanadium in the management of diabetes. Trends Pharmacol Sci 16: 265-270
31. Chen L, McNeill JR, Wilson TW, Gopalakrishnan V (1995) Differential effects of phosphoramidon on contractile responses to angiotensin II in rat blood vessels. Br J Pharmacol 114: 1599-1604
32. Becker DJ, Ongemba LN, Henquin JC (1994) Comparison of the effects of various vanadium salts on glucose homeostasis in streptozotocin diabetic rats. Eur J Pharmacol 260: 169-175
33. Yamauchi T, Ohnaka K, Takayanagi R, Umeda F, Nawata H (1990) Enhanced secretion of endothelin-1 by elevated glucose levels from cultured bovine aortic endothelial cells. FEBS Lett 267: 16-18
34. Boulanger CM, Luscher TF (1990) Release of endothelin from the porcine aorta. Inhibition by endothelium derived nitric oxide. J Clin Invest 85: 587-590
35. Yanagisawa M, Kurihara H, Kimura et al. (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411-415
36. Vane JR, Anggard EE, Botting RM (1990) Regulatory functions of the vascular endothelium. N Eng J Med 323: 27-36
37. Stout RW (1991) Insulin as a mitogenic factor: role in pathogenesis of cardiovascular disease. Am J Med 90:62S-65S
38. Scherrer U, Sartori C (1997) Insulin as a vascular and a sympathoexcitatory hormone. Circulation 96: 4104-4113
39. Kroc Collaborative Study Group (1984) Blood glucose control and the evolution of diabetic retinopathy and albuminuria. A preliminary multicentre trial. N Eng J Med 311: 365-372
40. Boscolo P, Carmignani M, Volpe AR et al. (1994) Renal toxicity and arterial hypertension in rats chronically exposed to vanadate. Occup Environ Med 51: 500-503
41. Sandirasegarane L, Gopalakrishnan V (1995) Vanadate increases cytosolic free calcium in rat aortic smooth muscle cells. Life Sci 56:PL169-PL174