The CLIP-substituted invariant chain efficiently targets an antigenic peptide to HLA class II pathway in L cells

Human Immunology

Volumn 59, Issue 10, 1998, Pages 607-614

  Fujii, Shinji ^a,b   Senju, Satoru ^a   Chen, Yu Zhen ^a   Ando, Masayuki ^b   Matsushita, Sho ^a   Nishimura, Yasuharu ^a  

^a Division of Immunogenetics   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 2;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; IMMUNE RESPONSE; IMMUNOTHERAPY; L CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; ANTIGENS, BACTERIAL; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; CARRIER PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; GENES, MHC CLASS II; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-DR ANTIGENS; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES;

EID: 0031751045     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(98)00058-5     Document Type: Article

References (30)

1. York I.A., Rock K.L. Antigen processing and presentation by the class I major histocompatibility complex. Ann Rev Immunol. 14:1996;369.
2. Parra-Lopez C.A., Lindner R., Vidavsky I., Gross M., Unanue E.R. Presentation on class II MHC molecules of endogenous lysozyme targeted to the endocytic pathway. J Immunol. 158:1997;2670.
3. Wu T.C., Guarnieri F.G., Staveley O.C.K.F., Viscidi R.P., Levitsky H.I., Hedrick L., Cho K.R., August J.T., Pardoll D.M. Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens. Proc Natl Acad Sci USA. 92:1995;11671.
4. Sanderson S., Frauwirth K., Shastri N. Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteins. Proc Natl Acad Sci USA. 92:1995;7217.
5. Nakano N., Rooke R., Benoist C., Mathis D. Positive selection of T cells induced by viral delivery of neopeptides to the thymus. Science. 275:1997;678.
6. van Bergen J., Schoenberger S.P., Verreck F., Amons R., Offringa R., Koning F. Efficient loading of HLA-DR with a T helper epitope by genetic exchange of CLIP. Proc Natl Acad Sci USA. 94:1997;7499.
7. Strubin M., Long E.O., Mach B. Two forms of the Ia antigen-associated invariant chain result from alternative initiations at two in-phase AUGs. Cell. 47:1986;619.
8. O'Sullivan D.M., Noonan D., Quaranta V. Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation. J Exp Med. 166:1987;444.
9. Cresswell P. Assembly, transport, and function of MHC class II molecules. Ann Rev Immunol. 12:1994;259.
10. Roche P.A., Cresswell P. Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules. Proc Natl Acad Sci USA. 88:1991;3150.
11. Ghosh P., Amaya M., Mellins E., Wiley D.C. The structure of an intermediate in class II MHC maturation CLIP bound to HLA-DR3 . Nature. 378:1995;457.
12. Roche P.A., Marks M.S., Cresswell P. Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain. Nature. 354:1991;392.
13. Bakke O., Dobberstein B. MHC class II-associated invariant chain contains a sorting signal for endosomal compartments. Cell. 63:1990;707.
14. Pond L., Kuhn L.A., Teyton L., Schutze M.P., Tainer J.A., Jackson M.R., Peterson P.A. A role for acidic residues in di-leucine motif-based targeting to the endocytic pathway. J Biol Chem. 270:1995;19989.
15. Peters P.J., Neefjes J.J., Oorschot V., Ploegh H.L., Geuze H.J. Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature. 349:1991;669.
16. Tulp A., Verwoerd D., Dobberstein B., Ploegh H.L., Pieters J. Isolation and characterization of the intracellular MHC class II compartment. Nature. 369:1994;120.
17. Amigorena S., Drake J.R., Webster P., Mellman I. Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes. Nature. 369:1994;113.
18. Denzin L.K., Cresswell P. HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading. Cell. 82:1995;155.
19. Sloan V.S., Cameron P., Porter G., Gammon M., Amaya M., Mellins E., Zaller D.M. Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature. 375:1995;802.
20. Chen Y.Z., Matsushita S., Nishimura Y. Response of a human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide characterization and frequencies of TCR agonism and TCR antagonism with or without partial activation . J Immunol. 157:1996;3783.
21. Gregersen P.K., Goyert S.M., Song Q.L., Silver J. Microheterogeneity of HLA-DR4 haplotypes DNA sequence analysis of LD"KT2" and LD"TAS" haplotypes . Hum Immunol. 19:1987;287.
22. Inoko H, Bodmer JG, Heyes JM, Drover S, Trowsdale J, Marshall WH: Joint report on the transfectant/monoclonal antibody component. In Tsuji K, Aizawa M, Sasazuki T (eds). HLA 1991 vol 1, Oxford, Oxford University Press, 1992.
23. Denzin L.K., Robbins N.F., Carboy-Newcomb C., Cresswell P. Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells. Immunity. 1:1994;595.
24. Takebe Y., Seiki M., Fujisawa J., Hoy P., Yokota K., Arai K., Yoshida M., Arai N. SR alpha promoter an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat . Mol Cel Biol. 8:1988;466.
25. Ikagawa S., Matsushita S., Chen Y.Z., Ishikawa T., Nishimura Y. Single amino acid substitutions on a Japanese cedar pollen allergen (Cry j 1)-derived peptide induced alterations in human T cell responses and T cell receptor antagonism. J Allergy Clin Immunol. 97:1996;53.
26. + T cells specific to streptococcal antigen present in low but not in high responders. J Immunol. 146:1991;2560.
27. Möller P, Mordenhauer G: B-cell antigens: CD74 workshop panel report: In Kishimoto T, Kikutani H, von dem Borne AEGK, Goyert SM, Mason DY, Miyasaka M, Moretta L, Okumura K, Shaw S, Springer TA, Sugamura K, Zola H (eds): Leucocyte typing VI. p. 166. New York, Garland Publishing Inc, 1997.
28. Katz J.F., Stebbins C., Appella E., Sant A.J. Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules. J Exp Med. 184:1996;1747.
29. Riberdy J.M., Newcomb J.R., Surman M.J., Barbosa J.A., Cresswell P. HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides. Nature. 360:1992;474.
30. Ignatowicz L., Winslow G., Bill J., Kappler J., Marrack P. Cell surface expression of class II MHC proteins bound by a single peptide. J Immunol. 154:1995;3852.