Erythropoiesis in patients stimulated with erythropoietin: The relevance of storage iron

Vox Sanguinis

Volumn 75, Issue 2, 1998, Pages 128-133

  Goodnough, Lawrence Tim ^a,c   Marcus, Randall E ^b  

^a WASHINGTON UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; FERRITIN; IRON; RECOMBINANT ERYTHROPOIETIN; TRANSFERRIN;

ADULT; AGED; ARTICLE; BLOOD AUTOTRANSFUSION; BLOOD DONOR; ERYTHROCYTE; ERYTHROCYTE VOLUME; ERYTHROPOIESIS; FEMALE; HUMAN; IRON DEFICIENCY; IRON STORAGE; IRON THERAPY; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL;

ADULT; AGED; BLOOD DONORS; BLOOD TRANSFUSION, AUTOLOGOUS; ERYTHROPOIESIS; ERYTHROPOIETIN; FEMALE; HEMATOCRIT; HUMANS; IRON; MALE; MIDDLE AGED; PREOPERATIVE CARE; TRANSFERRIN;

EID: 0031750669     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1159/000030973     Document Type: Article

References (23)

1. Goodnough LT, Wasman J, Corlucci K, Chernosky A: Limitations to donating adequate autologous blood prior to elective orthopaedic surgery. Arch Surg 1989;124:494-496.
2. Kicker TS, Spivak JL: Effect of repeated whole blood donations on serum immunoreactive erythropoietin levels in autologous donors. JAMA 1988;260:65-67.
3. Goodnough LT, Brittenham GM: Limitations of the erythropoietin response to serial phlebotomy: Implications for autologous blood donor programs. J Lab Clin Med 1990;115:28-35.
4. Goodnough LT, Price TH, Rudnick S: Iron-restricted erythropoiesis as a limitation to autologous blood donation in the erythropoietin-stimulated bone marrow. J Lab Clin Med 1991;118: 289-296.
5. Goodnough LT, Price TH, Rudnicks S: Preoperative red cell production in patients undergoing aggressive autologous blood phlebotomy with and without recombinant human erythropoietin therapy. Transfusion 1992;32:441-445.
6. Coleman PH, Stevens AR, Dodge HT, Finch CA: Rate of blood regeneration after blood loss. Arch Intern Med 1953;92:341-348.
7. Hillman RS, Henderson PA: Control of marrow production by the level of iron supply. J Clin Invest 1969;48:454-460.
8. Harnstra RD, Block MH: Erythropoiesis in response to blood loss in man. J Appl Physiol 1969;27:503-507.
9. Finch CA: Erythropoiesis, erythropoietin, and iron. Blood 1982:60:1241-1246.
10. Skikne BS, Cook JD: Effect of enhanced erythropoiesis on iron asorption. J Lab Clin Med 1992;120:746-751.
11. Goodnough LT, Rudnick S, Price TH, et al: Increase preoperative collection of autologous blood with recombinant human erythropoietin therapy. N Engl J Med 1989;321:1163-1168.
12. Goodnough LT, Price TH, Friedman KD, Johnson M, Ciavarella D, Kahn N, Sacher R, Vogler WR, Wissel M, Abels RI: A phase III trial of recombinant human erythropoietin therapy in non-anemic orthopaedic patients subjected to aggressive autologous blood phlebotomy: Dose, response, toxicity, and efficacy. Transfusion 1994;34:66-71.
13. Price TH, Goodnough LT, Vogler WR, Sacher RA, Hellman RM, Johnston MFM, Bolgiano DC, Abels RI: The effect of recombinant human erythropoietin on the efficacy of autologous blood donation in patients with low hematocrits. Transfusion 1996;36:29-36.
14. Holland PV, Schmidt PH: Standards for Blood Banks and Transfusion Services, 14. Arlington, American Association of Blood Banks, 1991, p 40.
15. Miale JB: Laboratory Medicine Hematology. St. Louis, Mosby, 1982, pp 360-366.
16. Chaplin H, Mollison PI, Vetter H: The body/ venous hematocrit ratio: Its consistency over a wide range. J Clin Invest 1953;32:1309.
17. Goodnough LT, Johnston MFM, Toy PTCY, et al: The variability of transfusion practice in primary, elective coronary artery bypass graft surgery. JAMA 1991;265:86-90.
18. Goodnough LT, Bravo J, Hsueh Y, Keating L, Brittenham GM: Red blood cell volume in autologous and homologous blood units: Implications for risk/benefit assessment for autologous blood 'crossover' and directed blood transfusion. Transfusion 1989;29:821-822.
19. Brittenham GM: Disorders of iron metabolism: Iron deficiency and overload; in Huffman R (ed): Hematology: Basic Principles and Practice. New York, Churchill Livingstone, 1995, p 505.
20. Cook JD, Skikne BS, Lynch SR, Reysser ME: Estimates of iron sufficiency in the US population. Blood 1986;68:726-731.
21. Crosby WH: Treatment of hemochromatosis by energetic phlebotomy. One patient's response to getting 55 liters of blood in 11 months. Br J Haematol 1958;4:82-88.
22. Goodnough LT, Merker K: The use of parenteral iron and recombinant human erythropoietin therapy to stimulate erythropoiesis in patients undergoing repair of hip fracture. Int J Hematol 1996;1:163-166.
23. Mercuriali F, Zanella A, Barosi G, et al: Use of erythropoietin to increase the volume of autologous blood donated by orthopaedic patients. Transfusion 1993;33:55-59.