Selecting therapy for serious infections in children: Maximizing safety and efficacy

Diagnostic Microbiology and Infectious Disease

Volumn 31, Issue 2, 1998, Pages 405-410

  Bradley, John S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CARBAPENEM; CEFOTAXIME; CEFTRIAXONE; CILASTATIN PLUS IMIPENEM; MEROPENEM;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC THERAPY; BACTERIAL INFECTION; CHILD; CLINICAL TRIAL; CONFERENCE PAPER; DRUG CHOICE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; HOSPITAL INFECTION; HUMAN; MENINGITIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

EID: 0031750429     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0732-8893(98)00024-8     Document Type: Conference Paper

References (11)

1. Adam D. Use of quinolones in pediatric patients. Rev Infect Dis. 11:(suppl 5):1989;S1113-S1116.
2. Bradley J.S., Faulkner K.L., Klugman K.P. Efficacy, safety and tolerability of meropenem as empiric antibiotic therapy in hospitalized pediatric patients. Pediatr Infect Dis J. 15:1996;749-757.
3. Day I.P., Goudie J., Nishiki K., Williams P.D. Correlation between in vitro and in vivo models of proconvulsive activity with the carbapenem antibiotics, biapenem, imipenem/cilastatin and meropenem. Toxicol Lett. 76:1995;239-243.
4. De Sarro A., Ammendola D., Zappala M., Grasso S., De Sarro G.B. Relationship between structure and convulsant properties of some β-lactam antibiotics following intracerebroventricular microinjection in rats. Antimicrob Agents Chemother. 39:1995;232-237.
5. Edwards J.R. Meropenem a microbiological overview . J Antimicrob Chemother. 36:(suppl A):1995;1-17.
6. Hori S., Kanemitsu K., Shimada J. Epileptogenic activity of meropenem, a new carbapenem a comparative study on epileptogenic activity of carbapenems and β-lactams . Program and Abstracts of the 32nd Interscience Conference on Antimicrobial Agents and Chemotherapy (Anaheim, CA). 1992;American Society for Microbiology, Washington, DC. (abstr 301).
7. Klugman K.P., Dagan R. Randomized comparison of meropenem with cefotaxime for treatment of bacterial meningitis. Antimicrob Agents Chemother. 39:1995;1140-1146.
8. Rodriguez W., Bradley J.S., Odio C. Meropenem vs cefotaxime in the treatment of pediatric meningitis. Program and Abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy (Toronto, Canada). 1997;American Society for Microbiology, Washington, DC. (abstr LM-002).
9. Shimada J., Hori S., Kanemitsu K., Shoji Y., Nakashio S., Yanagawa A. A comparative study on the convulsant activity of carbapenems and β-lactams. Drugs Exp Clin Res. 18:1992;377-381.
10. Sunagawa M., Matsumura H., Sumita Y., Nouda H. Structural features resulting in convulsive activity of carbapenem compounds effect of C-2 side chain . J Antibiot (Tokyo). 48:1995;408-416.
11. Wong V.K., Wright H.T. Jr, Ross L.A., Mason W.H., Inderlied C.B., Kim K.S. Imipenem/cilastatin treatment of bacterial meningitis in children. Pediatr Infect Dis J. 10:1991;122-125.