Clinical spectrum associated with positive ANCA titres in 94 consecutive patients: Is there a relation with PR-3 negative c-ANCA and hypergammaglobulinaemia?

Annals of the Rheumatic Diseases

Volumn 57, Issue 3, 1998, Pages 141-145

  Blockmans, D ^a,b   Stevens, E ^a,b   Marien G ^b   Bobbaers, H ^a   Marien, G ^a  

^a Experimental Laboratory Immunology   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

NEUTROPHIL CYTOPLASMIC ANTIBODY;

ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CORRELATION FUNCTION; DIAGNOSTIC VALUE; DISEASE SEVERITY; HUMAN; HUMAN TISSUE; HYPERGAMMAGLOBULINEMIA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

EID: 0031749378     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.57.3.141     Document Type: Article

References (20)

1. van der \Voude FJ, Rasmussen N, Lobatto S, et al. Autoantibodies against neutrophils and monocytes : tool for diagnosis and marker of disease activity in Wegener's granulomatosis. Lancet 1985;i:425-9.
2. Davies DJ, Moran JE, Niall JF, Ryan GB. Segmental necrotising glomerulonephritis with antineutrophil antibody : possible arbovirus aetiology? BMJ 1982;285:606.
3. Jenette JC, Falk RJ. Antineutrophil cytoplasmic autoantibodies and associated diseases : a review. Am J Kidney Dis 1990;15:517-29.
4. Niles JL, McCluskey RT, Ahmad MF, Arnaout MA. \Vegener's granulomatosis autoantigen is a novel proteinase. Blood 1989;74:1888-93.
5. Falk RJ, Jennette JC. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med 1988;318: 1651-7.
6. Rump JA, Scholmerich J, Gross V, a al. A new type of perinuclear antineutrophil cytoplasmic antibody (p-ANCA) in active ulcerative colitis but not in Crohn's disease. Immunobiology 1990;181:406-13.
7. Peter HH, Metzger D, Rump A, Röther E. ANCA in diseases other than systemic vasculitis. Clin Exp Immunol 1993;91 (suppl 1):S12-14
8. Leavitt RY, Fauci AS, Bloch DA, ei al. The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis. Arthritis Rheum 1990;33: 1101-7.
9. Edgar JDM. The clinical utility of ANCA positivity. Ann Rheum Dis 1996;55:494-6.
10. Jennette JC. Anti-neutrophil cytoplasmic autoantibodyassociated disease: a pathologist's perspective. Am J Kidney Disease 1991;18:164-70.
11. Geffriaud-Ricouard L, Noel LH, Chauveau D, Houhou S, Grünfeld JP, Lesafre P. Clinical spectrum associated with ANCA of denned antigen specificities in 98 selected patients. ClinNephrol 1993;39:125-36.
12. Davenport A, Lock RJ, \Vallington TB, Feest TG. Clinical significance of anti-neutrophil cytoplasm antibodies detected by a standardised indirect immunofluorescence assay. Q J Med 1994;87:291-9.
13. Edgar JDM, McMillan SA, Bruce I, Conlan SK. An audit of ANCA in routine clinical practice. Postgrad Med J 1995:71:605-12.
14. Kallenberg CGM, Brouwer E, Weening JJ, Cohen Tervaert J\V. Anti-neutrophil cytoplasmic antibodies: current diagnostic and pathophysiological potential. Kidney Int 1994; 46:1-15.
15. Blockmans D, Vandenbon C, Macken T, Stevens E, Bobbaers H. VTegener's granulomatosis : a study on 50 patients. European Journal of Internal Aledicine 1997;8: 19-26.
16. Kerr GS, Fleisher TA, Hallahan C\V, et al. Limited prognostic value of changes in anti-neutrophil cytoplasmic antibody titer in patients with \X'egener's granulomatosis. Arthritis Rheum 1993;36:365-71.
17. Davenport A, Lock RJ, \Vallington T. Clinical significance of the serial measurement of autoantibodies to neutrophil cytoplasm using a standard indirect immunofluorescence test. Am J Nephrol 1995;15:201-7.
18. De'Oliveira J, Gaskin G, Dash A, Rees AJ, Pusey CD. Relationship between disease activity and anti-neutrophil cytoplasmic antibody concentration in long-term management of systemic vasculitis. Am J Kidney Dis 1995;25:380-9.
19. Klaassen RJL, Goldschmeding R, Dolman KM, el al. Antineutrophil cytoplasmic autoantibodies in patients with symptomatic H1V infection. Clin Exp Immunol 1992;87: 24-30.
20. Adebajo AO, Charles P, Maini RN, Hazleman BL. Autoantibodies in malaria, tuberculosis and hepatitis B in a VTest African population. Clin Exp Immunol 1993;92:73-6.