Nonanesthetic volatile drugs obey the Meyer-Overton correlation in two molecular protein site models

Anesthesiology

Volumn 88, Issue 6, 1998, Pages 1535-1548

  Forman, Stuart A ^a   Raines, Douglas E ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

Kinetic states; Mechanisms of anesthesia; Mutagenesis

Indexed keywords

1,2 DICHLOROHEXAFLUOROCYCLOBUTANE; 2,3 DICHLOROOCTAFLUOROBUTANE; ACETYLCHOLINE; CHLOROFORM; ENFLURANE; HALOTHANE; HUMAN SERUM ALBUMIN; INHALATION ANESTHETIC AGENT; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG; VOLATILE AGENT;

ANESTHESIA MECHANISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; FLUORESCENCE; HYDROPHOBICITY; MOLECULAR MODEL; NONHUMAN; OOCYTE; PARTITION COEFFICIENT; PATCH CLAMP; PRIORITY JOURNAL; XENOPUS;

ANESTHETICS, INHALATION; ANIMALS; DNA, COMPLEMENTARY; HUMANS; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; RECEPTORS, NICOTINIC; SERUM ALBUMIN; XENOPUS;

EID: 0031748366     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199806000-00018     Document Type: Article

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