Identification of elastin peptides with vasorelaxant activity on rat thoracic aorta

International Journal of Biochemistry and Cell Biology

Volumn 30, Issue 4, 1998, Pages 497-503

  Lograno, M D ^b   Bisaccia, F ^a   Ostuni, A ^a   Daniele, E ^b   Tamburro, A M ^a  

^a UNIVERSITY OF BASILICATA   (Italy)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

Aorta; Elastin peptides; Vasodilatation

Indexed keywords

ELASTIN; PEPTIDE; PHENYLEPHRINE;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; MALE; NONHUMAN; RAT; SIGNAL TRANSDUCTION; THORACIC AORTA; VASODILATATION;

ANIMALS; AORTA, THORACIC; ELASTIN; HUMANS; MALE; MUSCLE RELAXATION; PEPTIDE FRAGMENTS; PHENYLEPHRINE; RATS; RATS, WISTAR; VASOCONSTRICTOR AGENTS; VASODILATION;

ANIMALIA;

EID: 0031748006     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(98)00008-9     Document Type: Article

References (18)

1. J.M. Gosline, J. Rosenbloom, Elastin, in: K.A. Piez, A.H. Reddi (Eds.), Extracellular Matrix Biochemistry, Elsevier Science Publishing, New York, 1984, pp. 191-227.
2. Rucker R., Dubick M.A. Elastin, metabolism and chemistry: potential roles in lung development and structure. Environ Health Perspect. 55:1984;179-191.
3. Hornebeck W., Tixier J.M., Robert L. Inducible adhesion mesenchymal cells to elastic fibers: elastonectin. Proc. Natl. Acad. Sci. USA. 83:1986;5517-5520.
4. Netland P.A., Zetter B.R. Melanoma cell adhesion to define extra cellular matrix components. Biochem. Biophys. Res. Commun. 13:1986;515-522.
5. Tobias J.W., Bern M.M., Netland P.A., Zetter B.R. Monocytes adhesion to subendothelial components. Blood. 69:1987;1265-1268.
6. Senior R.M., Griffin G.L., Mecham R.P., Wrenn D.S., Prasad K.U., Urry D.W. Val-Gly-Val-Ala-Pro-Gly a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J. Cell. Biol. 99:1984;870-874.
7. Blood C.H., Sasse J., Brodt P., Zetter B.R. Identification of a tumour cell receptor for VGVAPG, an elastin-derived chemotactic peptides. J. Cell Biology. 107:1988;1987-1993.
8. Jacob M.P., Fulop T. Jr., Foris G., Robert L. Effect of elastin peptides on ion fluxes in mononuclear cells, fibroblasts and smooth muscle cells. Proc. Natl. Acad. Sci. USA. 84:1987;995-999.
9. Faury G., Ristori M.T., Verdetti J., Jacob M.P., Robert L. Effect of elastin peptides on vascular tone. Journal of Vascular Research. 32:1995;112-119.
10. Hinek A., Wrenn D.S., Mecham R.P., Barondes S.H. The elastin receptor: a galactoside-binding protein. Science. 239:1988;1539-1541.
11. Hornebeck W., Brechemier D., Jacob M.P., Fracès C., Robert L. On the multiplicity of cellular elastases and their inefficient control by natural inhibitors in Horl, Heidland. Proteases: potential role in health and disease. Adv. Exp. Med. Biol. 167:1984;111.
12. Fulop T. Jr., Wei S.M., Robert L., Jacob M.P. Determination of elastin peptides in normal and arteriosclerotic human sera by ELISA. Clin. Physiol. Biochem. 8:1990;273-282.
13. Bisaccia F., Castiglione Morelli M.A., De Biasi M., Traniello S., Spisani S., Tamburro A.M. Migration of monocytes in the presence of elastolytic fragments of elastin and in synthetic derivatives. Int. J. Peptide Protein Res. 44:1994;332-341.
14. Castiglione M.A., Bisaccia F., Spisani S., De Biasi M., Traniello S., Tamburro A.M. Structure-activity relationships for some elastin-derived peptide chemoattractants. J. Peptide Res. 49:1997;492-499.
15. Furchgott R.F., Zawadzki J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 302:1980;373-376.
16. L.G. Luna, Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology, 3rd ed. McGraw-Hill Book Company, New York, 1986.
17. L. Sandberg, P. Ross, A.M. Tamburro, Hydroxylation of the pentapeptide VGVPG in ovine elastin, in: The Molecular Biology and Pathology of Elastic Tissues, vol. 192, Ciba Foundation Wiley Symposium, J. Wiley and Sons, 1995, pp. 51-55.
18. Varga Z., Jacob M.P., Robert L., Fulop T. Jr. Identification and signal transduction mechanism of elastin peptide receptor in human leukocytes. FEBS Letters. 258:1989;5-8.