Anti-neutrophil cytoplasm autoantibodies (ANCA). The need for specific and sensitive assays

Autoimmunity

Volumn 27, Issue 4, 1998, Pages 231-238

  Baslund, Bo ^a   Petersen, Jørgen ^b  

^a HVIDOVRE HOSPITAL   (Denmark)

^b Rigshospitalet   (Denmark)

Author keywords

ANCA; Methodology; Myeloperoxidase; Proteinase 3

Indexed keywords

AUTOANTIBODY; BACTERICIDE; LACTOFERRIN; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ANTIBODY DETECTION; ANTIGEN PURIFICATION; ARTICLE; ASSAY; HUMAN; IMMUNOFLUORESCENCE; SYSTEMIC VASCULITIS;

EID: 0031746996     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939808993835     Document Type: Article

References (68)

1. Kallenberg, C. G. M., Brouwer, E., Weening, J. J. and Tervaert, J. W. C. (1994). Anti-neutrophil cytoplasmic antibodies: Current diagnostic and pathophysiological potential. Kidney Int, 46, 1-15.
2. Goldschmeding, R., van der School, C. E., ten Bokkel Huinink, D., et al. (1989). Wegener's granulomatosis auto-antibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils. J Clin Invest, 84, 1577-1587.
3. Jenne, D., Tschopp, J., Ludemann, J., Utecht, B. and Gross, W. (1990). Wegener's autoantigen decoded. Nature, 346, 520.
4. Niles, J. L., Mccluskey, R. T., Ahmad, M. F. and Arnaout, M. A. (1989). Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase. Blood. 74, 1888-1893.
5. Wiik, A., Rasmussen, N. and Wieslander, J. (1993). Methods to detect autoantibodies to neutrophilic granulocytes. In: Van Venrooij, W. J., Maini, R. N., eds. Manual of biological markers of disease, Dordrecht: Kluwer Academic Publishers, A9, 1-A914.
6. Hagen, E. C., Andrassy, K., Chernok, E., et al. (1993). The value of indirect immunofluorescence and solid phase techniques for ANCA detection. A report on the first phase of an international cooperative study on the standardization of ANCA assays. EEC/BCR Group for ANCA Assay Standardization. J Immunol Methods, 159, 1-16.
7. Goldschmeding, R. (1992). Target antigens of antineutrophil cytoplasmic antibodies. Amsterdam: Thesis.
8. Braun, M. G., Csernok, E., Gross, W. L. and Muller Hermelink, H. K. (1991). Proteinase 3, the target antigen of anticytoplasmic antibodies circulating in Wegener's granulomatosis. Immunolocalization in normal and pathologic tissues. Am J Pathol, 139, 831-838.
9. Egesten, A., Bretongorius, J., Guichard, J., Gullberg, U. and Olsson, I. (1994). The heterogenity of azurophil granules in neutrophil promyelocytes: Immunogold localization of myeloperoxidase, cathepsin, G. elastase, proteinase 3, and bactericidal permeability increasing protein. Blood, 83, 2984-2994.
10. Rao, N. V., Wehner, N. G., Marshall, B. C., Gray, W. R., Gray, B. H. and Hoidal, J. R. (1991). Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties. J Biol Chem, 266, 9540-9548.
11. Dalpe, G., Beliveau, A. and Menard, H. A. (1993). Cross-Reactivity of an Anti-Proteinase 3 Antibody to Elastase. Autoimmunity, 16, 311-313.
12. Nassberger, L., Hansson, A.-L. and Martensson, U. (1993). Lack of cross-reactivity of c-ANCA to elastase and cathepsin G. Autoimmunity, 14, 259.
13. Bini, P., Gabay, J. E., Teitel, A., Melchior, M., Zhou, J. L. and Elkon, K. B. (1992). Antineutrophil cytoplasmic autoantibodies in Wegener's granulomatosis recognize conformational epitope(s) on proteinase 3. J Immunol, 149, 1409-1415.
14. Plow, E. F. (1982). Leukocyte elastase release during blood coagulation. J Clin Invest, 69, 564-572.
15. Baslund, B., Segelmark, M., Wiik, A., Szpirt, W., Petersen, J. and Wieslander, J. (1995). Screening for anti-neutrophil cytoplasmic antibodies (ANCA): is indirect immunofluorescence the method of choice? Clin Exp Immunol, 99, 486-492.
16. Bergenfeldt, M., Axelsson, L. and Ohlsson, K. (1992). Release of neutrophil proteinase 4(3) and leukocyte elastase during phagocytosis and their interaction with proteinase inhibitors. Scand J Clin Lab Invest, 52, 823-829.
17. Weiss, S. J. (1989). Tissue destruction by neutrophils. N Engl J Med, 320, 365-376.
18. Venge, P., Bergstrand, H. and Håkansson, L. (1993). Neutrophils and eosinophils. In: W. N. Kelley, E. D. Harris, S. Ruddy, C. B. Sledge (Eds), Textbook of Rheumatology, 269-285.
19. Falk, R. J. and Jennette, J. C. (1988). Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and cresentic glomerulonephritis. N Engl J Med, 318, 1651-1657.
20. Wieslander, J. (1991). How are antineutrophil cytoplasmic autoantibodies detected? Am J Kidney Dis, 18, 154-158.
21. Gross, W. L., Schmitt, W. H. and Csernok, E. (1993). ANCA and associated diseases: immunodiagnostic and pathogenetic aspects. Clin Exp Immunol, 91, 1-12.
22. Zhao, M. H., Jones, S. J. and Lockwood, C. M. (1995). Bactericidal/permeability-increasing protein (BPI) is an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis. Clin Exp Immunol, 99, 49-56.
23. Pesce, A. J. and Michael, J. G. (1992). Artefacts and limitations of enzyme immunoassay. J Immunol Methods, 150, 111-119.
24. Segelmark, M., Baslund, B. and Wieslander, J. (1994). Some patients with anti-myeloperoxidase autoantibodies have a c-ANCA pattern. Clin Exp Immunol, 96, 458-465.
25. van der Woude, F. J., Rasmussen, N., Lobatto, S., et al. (1985). Autoantibodies against neutrophils and monocytes: Tool for diagnosis and marker of disease activity in Wegener's granulomatosis. Lancet, 1, 425-429.
26. Nolle, B., Specks, U., Ludemann, J., Rohrbach, M. S., DeRemee, R. A. and Gross, W. L. (1989). Anticytoplasmic autoantibodies: their immunodiagnostic value in Wegener granulomatosis. Ann Intern Med, 111, 28-40.
27. Cohen Tervaert. J. W., van der Woude, F. J., Fauci, A. S., et al. (1989). Association between active Wegener's granulomatosis and anticytoplasmic antibodies. Arch Intern Med, 149, 2461-2465.
28. Ludemann, J., Csernok, E., Ulmer. M., et al. (1990). Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis: immunodiagnostic value, monoclonal antibodies and characterization of the target antigen. Neth J Med, 36, 157-162.
29. Davenport, A., Lock, R. J., Wallington, T. B. and Feest, T. G. (1994). Clinical significance of anti-neutrophil cytoplasm antibodies detected by a standardized indirect immunofluorescence assay. Q J Med, 87, 291-299.
30. Rao, J. K., Allen, N. B., Feussner, J. R. and Weinberger, M. (1995). A prospective study of neutrophil cytoplasmic antibody (c-ANCA) and clinical criteria in diagnosing Wegener's granulomatosis. Lancet, 346, 926-931.
31. Savage, C. O. S., Winnearls, C. G., Jones, S. Marshall, P. D. and Lockwood, C. M. Prospective study of radioimmunoassay for antibodies against neutrophil cytoplasm in diagnosis of systemic vasculitis. Lancet, i, 1389-1393.
32. Savige, J. A., Yeung, S. P., Gallicchio, M. and Davies, D. J. (1989). Two ELISAs to detect anti-neutrophil cytoplasm antibodies (ANCA) in various vasculitides. Pathology, 21, 282-287.
33. Rasmussen, N., Sjolin, C., Isaksson, B., Bygren, P. and Wieslander, J. (1990). An ELISA for the detection of anti-neutrophil cytoplasm antibodies (ANCA). J Immunol Methods, 127, 139-145.
34. Goldschmeding, R., van der School, C. E., van der Snoek, M. A. and Von dem Bome, A. E. G. K. (1989). A monoclonal antibody against the 29 kD ANCA-antigen: Application as catching antibody in a sandwich-ELISA for ANCA detection. APMIS, 97(6), 47.
35. Sommarin, Y., Rasmussen, N. and Wieslander, J. (1995). Characterization of monoclonal antibodies to proteinase 3 and application in the study of epitopes for cANCA. Exp Nephrol, 3, 249-256.
36. Savige, J. A., Smith, C, Change. L. and Duggan, J. C. (1991). Anti-neutrophil cytoplasm antibodies (ANCA) in a patient with the vasculitis of myelodysplasia [letter]. Br J Haematol, 78, 583-584.
37. Niles, J. L. (1993). Value of tests for antineutrophil cytoplasmic autoantibodies in the diagnosis and treatment of vasculitis. Curr Opin Rheumatol, 5, 18-24.
38. Cohen Tervaert, J. W., Huitema, M. G., Hene, R. J., et al. (1990). Prevention of relapses in Wegener's granulomatosis by treatment based on antineutrophil cytoplasmic antibody titre. Lancet, 336, 709-711.
39. Kerr, G. S., Fleisher, T. A., Hallahan, C. W., Leavitt, R. Y., Fauci, A. S. and Hoffman, G. S. (1993). Limited Prognostic-Value of Changes in Antineutrophil Cytoplasmic Antibody Titer in Patients with Wegener's Granulomatosis. Arthritis Rheum, 36, 365-371.
40. Hoffman, G. S., Kerr, G. S., Leavitt, R. Y., et al. (1992). Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med, 116, 488-498.
41. Cohen Tervaert, J. W., Mulder, L., Stegeman, C., et al. (1993). Occurrence of autoantibodies to human leucocyte elastase in Wegener's granulomatosis and other inflammatory disorders. Ann Rheum Dis, 52, 115-120.
42. Fienberg, R., Mark, E. J., Goodman, M., Mccluskey, R. T. and Miles, J. L. (1993). Correlation of antineutrophil cytoplasmic antibodies with the extrarenal histopathology of Wegener's (pathergic) granulomatosis and related forms of vasculitis. Hum Pathol, 24, 160-168.
43. Gaskin, G., Savage, C. O., Ryan, J. J., et al. (1991). Anti-neutrophil cytoplasmic antibodies and disease activity during long-term follow-up of 70 patients with systemic vasculitis. Nephrol Dial Transplant, 6, 689-694.
44. Cohen Tervaert, J. W., Goldschmeding, R., Elema, J., et al. (1990). Association of autoantibodies to myeloperoxidase with different forms of vasculitis. Arthritis Rheum, 33, 1264-1268.
45. Guillevin, L., Visser, H., Noel, L. H., et al. (1993). Anti-neutrophil cytoplasm antibodies in systemic polyarteritis nodosa with and without hepatitis B virus infection and Churg-Strauss syndrome-62 patients. J Rheumatol, 20, 1345-1349.
46. Cohen Tervaert, J. W., Limburg, P. C., Elema, J. D., et al. (1991). Detection of autoantibodies against myeloid lysosomal enzymes: A useful adjunct to classification of patients with biopsy-proven necrotizing arteritis. Am J Med, 91, 59-66.
47. Guillevin, L. and Lhote, F. (1995). Distinguishing polyarteritis nodosa from microscopic polyangiitis and implications for treatment. Curr Opin Rheumatol. 7, 20-24.
48. Savage, C. O., Tizard, J., Jayne, D., Lockwood, C. M. and Dillon, M. J. (1989). Antineutrophil cytoplasm antibodies in Kawasaki disease. Arch Dis Child, 64, 360-363.
49. Shaw, G., Ronda, N., Bevan, J. S., Esnault, V., Griffiths, D. F. and Rees, A. (1992). Antineutrophil cytoplasmic antibodies (ANCA) of IgA class correlate with disease activity in adult Henoch-Schonlein purpura. Nephrol Dial Transplant, 7, 1238-1241.
50. O'Donoghue, D. J., Nusbaum, P. Noel, L. H., Halbwachs Mecarelli, L. and Lesavre, P. (1992). Antineutrophil cytoplasmic antibodies in IgA nephropathy and Henoch-Schonlein purpura. Nephrol Dial Transplant, 7, 534-538.
51. Ronda, N., Esnault, V. L. M., Layward, L., et al. (1994). Antineutrophil cytoplasm antibodies (ANCA) of IgA isotype in adult Henoch-Schonlein purpura. Clin Exp Immunol, 95, 49-55.
52. Sinico, R. A., Tadros, M., Radice, M., et al. (1994). LAck of IgA antineutrophil cytoplasmic antibodies in Henoch-Schönlein purpura and IgA nephropathy. Clin Immunol Immunopathol, 73, 19-26.
53. McHugh, N. J., James, I. E. and Plant, G. T. (1990). Anti-cardiolipin and antineutrophil antibodies in giant cell arteritis. J Rheumatol, 17, 916-922.
54. Baranger, T. A. R., Audrain, M A. P., Castagne, A., Barrier, J. H. and Esnault, V. L. M. (1994). Absence of antineutrophil cytoplasmic antibodies in giant cell arteritis. J Rheumatol, 21, 871-873.
55. Coremans, I. E., Hagen, E. C., Daha, M. R., et al. (1992). Antilactoferrin antibodies in patients with rheumatoid arthritis are associated with vasculitis. Arthritis Rheum, 35, 1466-1475.
56. Mulder, A. H. L., Horst, G., van Leeuwen, M., Limburg, P.C. and Kallenberg, C. G. M. (1993). Anti-neutrophil cytoplasmic antibodies in rheumatoid arthritis: characterization and clinical correlates. Arthritis Rheum, 36, 1054-1060.
57. Mulder, A. H. L. (1994). Anti-neutrophil cytoplasmic antibodies in idiopathic inflammatory disorders. Thesis, Groningen.
58. Cambridge, G., Williams, M., Leaker, B., Corbett, M. and Smith, C. R. (1994). Anti-Myeloperoxidase Antibodies in Patients with Rheumatoid Arthritis - Prevalence, Clinical Correlates, and IgG Subclass. Ann Rheum Dis, 53, 24-29.
59. Dolman, K. M., Gans, R. O. B., Vervaat, T. J., et al. (1993). Vasculitis and Antineutrophil Cytoplasmic Autoantibodies Associated with Propylthiouracil Therapy. Lancet, 342, 651-652.
60. Saxon, A. Shanahan, F. Landers, C. Ganz, T. and Targan, S. (1990). A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. J Allergy Clin Immunol, 86, 202-210.
61. Mulder, A. H. L., Broekroelofs, J Horst, G., Limburg, P. C., Nelis, G. F. and Kallenberg, C. G. M. (1994). Anti-Neutrophil Cytoplasmic Antibodies (Anca) in Inflammatory Bowel Disease - Characterization and Clinical Correlates. Clin Exp Immunol, 95, 490-497.
62. Rump, J. A., Scholmerich, J., Gross, V., et al. (1990). A new type of perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) in active ulcerative colitis but not in Crohn's disease. Immunobiology, 181, 406-413.
63. Peen, E., Almer, S., Bodemar, G., et al. (1993). Antilactoferrin antibodies and other types of ANCA in ulcerative colitis, primary sclerosing cholangitis, and Crohn's disease. Gut, 34, 56-62.
64. Ellerbroek, M., Pool, M. O., Ridwan, B. U., et al. (1994). Neutrophil Cytoplasmic Antibodies (P-Anca) in Ulcerative Colitis. J Clin Pathol, 47, 257-262.
65. Broekroelofs, J., Mulder, A. H. L., Nelis, G. F., Westerveld, B. D., Tervaert, J. W. C. and Kallenberg, C. G. M. (1994). Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in Sera from Patients with Inflammatory Bowel Disease (IBD) - Relation to Disease Pattern and Disease Activity. Dig Dis Sci, 39, 545-549.
66. Coremans, I. E. M., Hagen, E. C., Vandervoort, E. A. M., Vanderwoude, F. J., Daha, M. R. and Breedveld, F. C. (1993). Autoantibodies to Neutrophil Cytoplasmic Enzymes in Felty's Syndrome. Clin Exp Rheumatol, 11, 255-262.
67. Pauzner, R., Urowitz, M., Gladman, D. and Gough, J. (1994). Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus. J Rheumatol, 21, 1670-1673.
68. Schnabel, A., Csernok, E., Isenberg, D. A., Mrowka, C. and Gross, W. (1995). Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus. Arthritis Rheum, 38, 633-637.