Morphology and surface properties of blends of Eudragit RS with different poly(ethylene glycol)s

Pharmaceutical Development and Technology

Volumn 3, Issue 1, 1998, Pages 123-129

  Lovrecich, Mara ^a   Rubessa, Fulvio ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Eudragit RS; Poly(ethylene glycol); Polymeric blends; Scanning electron microscopy; Surface properties

Indexed keywords

EUDRAGIT RS; MACROGOL; MACROGOL 20000; MACROGOL 6000; MACROGOL DERIVATIVE; PEG 14000; PEG 3400; UNCLASSIFIED DRUG;

ARTICLE; CONTACT ANGLE; DISPERSION; EMULSION; FILM COATING; PHASE SEPARATION; PHASE TRANSITION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; SURFACE TENSION;

EID: 0031746496     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.3109/10837459809028486     Document Type: Article

References (12)

1. P. Sakellariou and R. C. Rowe, The morphology of blends of ethyl cellulose with hydroxy propylmethylcellulose as used in film coating, Int. J. Pharm., 125, 289-296 (1995).
2. P, Sakellariou, R. C. Rowe, and E. F. T. White, A study of the leaching/retention of water soluble polymers in blends with ethylcelluose using torsional braid analysis, J. Controlled Release, 7, 147-157 (1988).
3. C. R. Rowe, Adhesion-substrate interaction in granulation. A theoretical approach based on surface free energy and polarity, Int. J. Pharm., 52, 149-154 (1989).
4. B. A. Johnson and G. Zografi, Adhesion of hydroxypropylcellulose films to low energy solid substrates, J. Pharm. Sci., 75, 529-533 (1986).
5. J. F. Pinto, G. Buckton, and J. M. Newton, A relationship between surface energy and polarity data and some physical properties of spheroids, Int. J. Pharm., 118, 95-101 (1995).
6. P. Esposito, I. Colombo, and M. Lovrecich, Investigation of surface properties of some polymers by a thermodynamic and mechanical approach: possibility of predicting mucoadhesion and biocompatibility, Biomaterials, 15, 177-182 (1994).
7. K. O. R. Lehmann, Chemistry and application properties of polymethacrylate coating systems, in Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms (J. W. Mc Ginity, ed.), Marcel Dekker, New York, 1989, pp. 1-94.
8. A. B. D. Cassie and S. Baxter, Wettability of porous surfaces, Trans. Faraday Soc., 40, 546-551 (1954).
9. S. Wu and K. Brzozowski, Surface free energy and polarity of organic pigments, J. Colloid Interface Sci., 38, 686-690 (1971).
10. G. Zografi and S. T. Tam, Wettability of pharmaceutical solids: Estimate of solid surface polarity, J. Pharm. Sci., 65, 1145-1149 (1976).
11. S. Wu, Polar and non-polar interaction in adhesion, J. Adhesion, 5, 39-55 (1973).
12. S. Wu, Calculation of interfacial tensions in polymer systems, J. Polym. Sci., C34, 19-30 (1971).