The murine Cdx1 gene product localises to the proliferative compartment in the developing and regenerating intestinal epithelium

Differentiation

Volumn 64, Issue 1, 1998, Pages 11-18

  Subramanian, Vasanta ^a   Meyer, Barbara ^b   Evans, Gareth S ^c,d  

^a UNIVERSITY OF BATH   (United Kingdom)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c CHRISTIE HOSPITAL   (United Kingdom)

^d SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL REGENERATION; COLUMNAR EPITHELIUM; CYTOLOGY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; HOMEOBOX; INTESTINE CRYPT; INTESTINE EPITHELIUM; INTESTINE VILLUS; MALE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RADIATION INJURY; TISSUE DISTRIBUTION;

EID: 0031742867     PISSN: 03014681     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-0436.1998.6410011.x     Document Type: Article

References (33)

1. Beck F, Erler T, Russell A, James R (1995) Expression of Cdx-2 in the mouse embryo and placenta: possible role in patterning of the extra-embryonic membranes. Dev Dyn 204: 219-227
2. Bjerknes M, Cheng H (1981) The stem cell zone of the mouse small intestinal epithelium. I. Evidence from Paneth cells in the adult mouse. Am J Anat 160:51-64
3. Chawengsaksophak K, James R, Hammond VE, Kontgen F, Beck F (1997) Homeosis and intestinal tumours in Cdx2 mutant mice. Nature 386:84-87
4. Cheng H, Leblond CP (1974) Origin and differentiation of the four main epithelial cell types in the mouse small intestine. V. Unitarian origin of the four epithelial cell types. Am J Anat 14:537-562
5. Cohn SM, Simon TC, Roth KA, Birkenmeier EH, Gordon JI (1992) Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein (Fabp) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axis of the gut epithelium. J Cell Biol 119:27-44
6. Duluc I. Jost B, Freund J-N (1993) Multiple levels of control of the stage specific and region specific expression of rat intestinal lactase. J Cell Biol 123:1577-1586
7. Duluc I, Freund JN, Lerberquier C, Kedinger M (1994) Fetal endoderm primarily holds the temporal and positional information required for mammalian intestinal development. J Cell Biol 126:211-221
8. Duprey P, Chowdury K, Dressler G, Balling R, Simon LD, Guenet J-L, Gruss P (1988) A mouse gene homologous to the Drosophila gene Caudal is expressed in epithelial cells in the embryonic intestine. Genes Dev 2:1647-1654
9. Evans GS, Chawalinski S, Owen G, Booth C, Singh A, Potten CS (1994) Expression of pokeweed lectin binding in murine intestinal Paneth cells. Epithelial Cell Biol 3:7-15
10. Flint N, Cove FL, Evans GS (1991) A low temperature method for the isolation of small intestinal epithelium along the cryptvillus axis. Biochem J 280:331-334
11. Freund J-N, Boukamel R, Benazzouz A (1992) Gradient of expression of Cdxl along the rat intestine throughout post-natal development. FEBS Lett. 314:163-166
12. Frumkin A, Pillemer G, Haffner R, Tarci N, Gruenbaum Y, Fainsod A (1991) A chicken caudal homologue Chox Cad is expressed in the epiblast with posterior localization in the early endodermal lineage. Development: 12,207-219
13. Gamer LW, Wright CVE (1993) Murine Cdx4 bears striking similarities to the Drosophila caudal gene in its homeodomain sequence and early expression pattern. Mech Dev 43:71-81
14. German MS, Wang J, Chadwick RB, Rutter WJ (1992) Synergistic activation of the insulin gene by a LIM homeodomain protein and the basic helix-loop-helix protein: building a functional insulin mini enhancer complex. Genes Dev 6: 2165-2176
15. Hendry JH, Potten CS, Ghaffer A, Moore JV, Roberts SA, Williams PC (1989) The response of murine intestinal crypts to short range promethium-147 irradiation: deductions concerning clonogenic cell numbers and positions: Radiat Res 118:364-374
16. James R, Kazenwadel J (1991) Homeobox gene expression in the intestinal epithelium of adult mice. J Biol Chem 266: 3246-3251
17. James R, Erlers T, Kazenwadel J (1994) Structure of the murine homeobox gene edx2. J Biol Chem 269:15229-15237
18. Kaur P, Potten CS (1986) Cell migration velocities in the crypts of the small intestine after cytotoxic insult are not dependent on mitotic activity Cell Tissue Kinet 19:601-610
19. Kedinger M, Simon PM, Grenier JF, Haffen K (1981) Role of epithelial-mesenchymal interactions in the ontogenesis of intestinal brush border enzymes. Dev Biol 86:339-347
20. Khyse-Anderson J (1984) Electroblotting of multiple gels. A simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide gels to nitrocellulose. J Biochem Biophys Methods 10:203-209
21. Laemmli EK (1970) Cleavage of structural proteins during the assembly of the head of bactriophage T4. Nature: 227: 680-685
22. Macdonald PM, Struhl G (1986) A molecular gradient in early Drosophila embryos and its role in specifying the body pattern. Nature 324:537-545
23. Mathan M, Moxey PC, Trier JS (1976) Morphogenesis of fetal rat duodenal villi. Am J Anat 146:73-92
24. McGinnis W, Krumlauf R (1992) Homeobox genes and axial patterning. Cell 68:283-302
25. Meyer B, Gruss P (1993) Mouse Cdx 1 expression during gastrulation. Development 117:191-203
26. Mlodzik M, Fjose A, Gehring WJ (1985) Isolation of caudal, a Drosophila homeobox containing gene with maternal expression whose transcripts form a concentration gradient at the preblastoderm stage. EMBO J 4:2961-2969
27. Potten CS, Hendry JH (1985) The micro-colony assay in mouse small intestine. In: Potten CS, Hendry JH (eds) Cell clones. Churchill-Livingstone, London, pp 50-60
28. Potten CS, Hendry JH, Moore JV (1987) Estimates of the number of clonogenic cells in the crypts of the murine small intestine. Virchows Arch 53:227-234
29. Raul F, Gosse F, Doffoel M, Darmenton P, Wessely JY (1988) Age related increase of brush border enzyme activities along the small intestine. Gut 29:1557-1563
30. Rubin DC, Swietlick E, Roth KA, Gordon JI (1992) Use of fetal intestinal isografts from normal and transgenic mice to study the programming of positional information along the duodenal-to-colonic axis. J Biol Chem 267:15122-15133
31. Sweetser DA, Hauft SM, Hoppe PC, Birkemeier EH, Gordon JI (1988) Transgenic mice containing intestinal fatty acid binding protein-human growth hormone fusion gene exhibit correct regional and cell specific expression of the reporter gene in their small intestine. Proc Natl Acad Sci U S A 85: 9611-9615
32. Subramanian V, Meyer BI, Gruss P (1995) Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell 83:641-653
33. Wright NA, Alison M (1984) Kinetic parameters in the gastro intestinal mucosa. In: Wright NA, Alison M (eds) Biology of epithelial cell populations, vol 2. Clarendon Press, Oxford, pp 634-687