Proliferative activity in placentas with hydropic change and hydatidiform mole as detected by Ki-67 and proliferating cell nuclear antigen immunostaining

American Journal of Clinical Pathology

Volumn 110, Issue 6, 1998, Pages 776-781

  Ostrzega, Nora ^a   Phillipson, Julia ^b   Liu, Paul ^a  

^a OLIVE VIEW UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Hydatidiform mole; Ki 67; Proliferating cell nuclear antigen immunostaining; Proliferative activity

Indexed keywords

CYCLINE;

ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; CELL PROLIFERATION; HUMAN; HUMAN TISSUE; HYDATIDIFORM MOLE; IMMUNOHISTOCHEMISTRY; PLACENTA; PRIORITY JOURNAL; TISSUE SECTION; TROPHOBLAST; TROPHOBLASTIC DISEASE;

EID: 0031742035     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcp/110.6.776     Document Type: Article

References (41)

1. Fox H, ed. Obstetrical and Gynecological Pathology. 3rd ed. Edinburg, Scotland: Churchill Livingstone; 1991:1045-1078.
2. Elston CW. Trophoblastic disease: a review with emphasis on recent advances and problems in differential diagnosis. In: Damjanov I, Cohen AH, Mills SE, et al, eds: Progress in Reproductive and Urinary Tract Pathology. New York, NY: Field and Wood;1989:37-71.
3. Driscoll SG. Gestational trophoblastic neoplasms: morphologic considerations. Hum Pathol. 1997;8:529-539.
4. Brewster II, Torok EE, Kahan BD, et al. Gestational trophoblastic disease; origin of choriocarcinoma, invasive mole and choriocarcinoma associated with hydatidiform mole and some immunologic aspects. Adv Cancer Res. 1971;27:89-147.
5. Hertig AT, Sheldon WH. Hydatidiform mole: a pathologico-clinical correlation of 200 cases. Am J Obstet Gynecol. 1947;53:1-36.
6. Kurman RJ, ed. Blaustein's Pathology of the Female Genital Tract. 4th ed. New York, NY: Springer-Verlag; 1994:1058-1059.
7. Federschneider JM, Goldstein DP, Berkowitz RS, et al. Natural history of recurrent molar pregnancy. Obstet Gynecol 1980;55:457-459.
8. Lurain JR, Sand RP, Carson SA, et al. Pregnancy outcome subsequent to consecutive hydatidiform moles. Am J Obstet Gynecol. 1982;142:1060-1061.
9. Szulman AE, Surti U. The syndromes of hydatidiform mole. I. Cytogenetic and morphologic correlations. Am J Obstet Gynecol. 1978;131:665-671.
10. Szulman AE, Surti U. The syndromes of hydatidiform mole. II. Morphologic evolution of the complete and partial mole. Am J Obstet Gynecol. 1978;132:20-27.
11. Szulman AE, Surti U. The clinicopathologic profile of the partial hydatidiform mole. Obstet Gynecol. 1982;59:597-602.
12. Gardner HA, Chir MB, Lage J. Choriocarcinoma following a partial hydatidiform mole: a case report. Hum Pathol. 1992; 23:468-471.
13. Abaci F, Aterman K. Changes of the placenta and embryo in early spontaneous abortion. Am J Obstet Gynecol. 1968;102: 252-263.
14. Elston CW. The histopathology of trophoblastic tumors. J Clin Pathol. 1976;10(suppl):111-131.
15. Javey H, Borazjani G, Behmard S, et al. Discrepancies in the histological diagnosis of hydatidiform mole. Am J Obstet Gynecol. 1979;86:480-483.
16. Brescia RJ, Kurman RJ, Main CS, et al. Immunocytochemical localization of chorionic gonadotropin, placental lactogen, and placental alkaline phosphatase in the diagnosis of complete and partial hydatidiform moles. Int J Gynecol Pathol. 1987;6:213-229.
17. Mathews MB, Bernstein RM, Fransa BR Jr, et al. Identity of the proliferating cell nuclear antigen and cyclin. Nature. 1984;309:374-376.
18. Hall PA, Levison DA, Woods AL, et al. Proliferating cell nuclear antigen (PCNA) immuno-localization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol. 1990;162: 285-294.
19. Hsu SM, Raine L, Gaagen H. A use of avidin-biotin-peroxidase complex in immunoperoxidase techniques. Am J Clin Pathol. 1981;75:816-821.
20. Verhuijen R, Kuijpers HJH, Schlengemann RO, et al. Ki-67 detects nuclear matrix-associated proliferation related antigen: I. Intracellular localization during interphase. J Cell Sci. 1989;92:123-130.
21. Cattoretti G, Becker MHG, Key G, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB1 and MIB3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol. 1992;168:357-363.
22. Berkowitz RS, Goldstein DP. Gestational trophoblastic disease. Cancer. 1995;76(suppl):2079-2085.
23. Baergen R, Kelly T, McGinniss M, et al. Complete hydatidiform mole with a coexistent embryo. Hum Pathol. 1996;27:731-734.
24. Keep D, Zaragoza M, Hassold T, et al. Very early complete hydatidiform mole. Hum Pathol. 1996;27:708-713.
25. Lindor NM, Ney JA, Gaffet TA, et al. A genetic review of complete and partial hydatidiform moles and nonmolar triploidy. Mayo Clin Proc. 1992;67:791-799.
26. Conran RM, Hitchcock CL, Norris HJ, et al. Diagnostic considerations in molar gestations. Hum Pathol. 1992;24:41-48.
27. Lawler SD, Fisher RA, Pickthall VJ, et al. Genetic studies on hydatidiform moles: I. The origin of partial moles. Cancer Genet Cytogenet. 1982;5:309-320.
28. Lage JM, Popek E. The role of DNA flow cytometry in evaluation of partial and complete hydatidiform moles and hydropic abortions. Semin Diagn Pathol. 1993;10:267-274.
29. Bell DA, Flotte TJ, Pastel-Levy C. Flow cytometric analysis of DNA content in partial hydatidiform moles with persistent gestational trophoblastic tumor. Obstet Gynecol. 1991;177: 111-115.
30. Lage JM, Weinberg DS, Jyavner DL, et al. The biology of tetraploid hydatidiform moles: histopathology, cytogenetics, and flow cytometry. Hum Pathol. 1989;20:419-425.
31. Fukunaga M, Shinichiro U, Fukunaga M, et al. Application of flow cytometry in diagnosis of hydatidiform moles. Mod Pathol. 1993;6:353-359.
32. Herbert DJ, Nishiymana RH, Bagwell CB, et al. Effects of several commonly used fixatives on DNA and total nuclear protein analysis by flow cytometry. Am J Clin Pathol. 1989;91:539-541.
33. Pelosi G, Bresaola E, Bogina G, et al. Endocrine tumors of the pancreas: Ki-67 immunoreactivity on paraffin sections is an independent predictor for malignancy: A comparative study with proliferating-cell nuclear antigen and progesterone receptor protein immunostaining, mitotic index, and other clinicopathologic variables. Hum Pathol. 1996;27:1124-1134.
34. Veronese S, Gambacorta M. Detection of Ki-67 proliferation rate in breast cancer. Correlation with clinical and pathologic features. Am J Clin Pathol. 1991;95:30-34.
35. Ng IO, Lai ECS, Fan ST, et al. Prognostic significance of proliferating cell nuclear antigen expression in hepatocellular carcinoma. Cancer. 1994;73:2268-2274.
36. Lam KJ, Law SYK, Mike KPS, et al. Prognostic implication of proliferative markers MIB-1 and PC 10 in esophageal squamous cell carcinoma. Cancer. 1996;77:7-13.
37. Weidner N, Moore D, Vartanian R. Correlation of Ki-67 antigen expression with mitotic figure index and tumor grade in breast carcinomas using the novel "paraffin"-reactive MIB1 antibody. Hum Pathol 1994;25:337-342.
38. Cheville JC, Robinson R, Benda JA. Evaluation of Ki-67 (MIB1) in placentas with hydropic change and partial and complete hydatidiform mole. Pediatr Pathol Lab Med. 1996;16:41-50.
39. Wolf HK, Michalopoulos GK. Proliferating cell nuclear antigen in human placenta and trophoblastic disease. Pediatr Pathol. 1992;12:147-154.
40. Cheung ANY, Ngan HYS, Chen WZ, et al. The significance of proliferating cell nuclear antigen in human trophoblastic diseases: an immuno-histochemical study. Histopathology. 1993;22:565-568.
41. Suresh UR, Hale RJ, Fox H, et al. Use of proliferation cell nuclear antigen for distinguishing hydropic abortions from partial hydatidiform moles. J Clin Pathol. 1993;46(1):48-50.