메뉴 건너뛰기




Volumn 9, Issue 8, 1998, Pages 483-487

Abdominal obesity and cardiovascular risk in children

Author keywords

Abdominal fat; Adolescents; Children; Fat distribution; Insulin; Lipids; Obesity

Indexed keywords

GLUCOSE; INSULIN; LIPID;

EID: 0031740568     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-199809080-00003     Document Type: Review
Times cited : (56)

References (35)
  • 3
    • 0030900718 scopus 로고    scopus 로고
    • Secular increases in relative weight and adiposity among children over two decades: The Bogalusa Heart Study
    • Freedman DS, Srinivasan SR, Valdez RA, Williamson DF, Berenson GS. Secular increases in relative weight and adiposity among children over two decades: the Bogalusa Heart Study. Pediatrics 1997; 99:420-426.
    • (1997) Pediatrics , vol.99 , pp. 420-426
    • Freedman, D.S.1    Srinivasan, S.R.2    Valdez, R.A.3    Williamson, D.F.4    Berenson, G.S.5
  • 6
    • 0024420287 scopus 로고
    • Childhood risk factors for high adult blood pressure: The Muscatine study
    • Lauer RM, Clarke WR. Childhood risk factors for high adult blood pressure: The Muscatine study. Pediatrics 1984; 84:633-641.
    • (1984) Pediatrics , vol.84 , pp. 633-641
    • Lauer, R.M.1    Clarke, W.R.2
  • 7
  • 8
    • 0023573935 scopus 로고
    • Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in US population aged 20-74 years
    • Harris MI, Haddem WC, Knowler WC, Bennett PH. Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in US population aged 20-74 years. Diabetes 1987; 36:523-534.
    • (1987) Diabetes , vol.36 , pp. 523-534
    • Harris, M.I.1    Haddem, W.C.2    Knowler, W.C.3    Bennett, P.H.4
  • 10
    • 0028117047 scopus 로고
    • Peripheral and abdominal adiposity in childhood obesity
    • Brambilla P, Manzoni P, Sironi S, Simone P, Del Maschio A, Di Natale B, et al. Peripheral and abdominal adiposity in childhood obesity. Int J Obes 1994; 18:795-800. One of the first papers to examine the link between direct measures of visceral and subcutaneous abdominal fat (by MRI) and metabolic risk factors in children. In obese Caucasian children and adolescents, visceral fat was associated with greater blood total- and LDL-cholesterol, and triglycerides.
    • (1994) Int J Obes , vol.18 , pp. 795-800
    • Brambilla, P.1    Manzoni, P.2    Sironi, S.3    Simone, P.4    Del Maschio, A.5    Di Natale, B.6
  • 11
    • 0028836569 scopus 로고
    • Central adiposity and its metabolic correlates in obese adolescent girls
    • Caprio S, Hyman LD, Limb C, McCarthy S, Lange R, Sherwin RS, et al. Central adiposity and its metabolic correlates in obese adolescent girls. Am J Physiol 1995; 269:E118-E126. This study used euglycemic and hyperglycemic clamp techniques to demonstrate impaired glucose disposal, and a failure to increase glucose oxidation and suppress lipid oxidation in response to insulin infusion in obese versus non-obese Caucasian adolescents. This study also provided direct evidence of a relationship between visceral fat and insulin secretion and insulin sensitivity in obese, but not in non-obese female adolescents.
    • (1995) Am J Physiol , vol.269
    • Caprio, S.1    Hyman, L.D.2    Limb, C.3    McCarthy, S.4    Lange, R.5    Sherwin, R.S.6
  • 12
    • 0029947796 scopus 로고    scopus 로고
    • Fat distribution and cardiovascular risk factors in obese adolescent girls: Importance of the intra-abdominal fat depot
    • Caprio S, Hyman LD, McCarthy S, Lange R, Bronson M, Tamborlane WV. Fat distribution and cardiovascular risk factors in obese adolescent girls: importance of the intra-abdominal fat depot. Am J Clin Nutr 1996; 64:12-17. This study provided direct evidence of the link between visceral fat (by MRI) and an adverse lipid profile in obese, predominantly Caucasian adolescent girls. Visceral fat was positively correlated with triglycerides and negatively with HDL cholesterol.
    • (1996) Am J Clin Nutr , vol.64 , pp. 12-17
    • Caprio, S.1    Hyman, L.D.2    McCarthy, S.3    Lange, R.4    Bronson, M.5    Tamborlane, W.V.6
  • 13
    • 0031957553 scopus 로고    scopus 로고
    • Fat distribution and insulin response in prepubertal African American and White children
    • Gower BA, Nagy TR, Trowbridge CA, Dezenberg C, Goran MI. Fat distribution and insulin response in prepubertal African American and White children. Am J Clin Nutr 1998; 67:821-827. The only published study to date examining the metabolic correlates of visceral fat in a sample comprised entirely of pre-pubertal children (Tanner stage I). Although both visceral and subcutaneous abdominal fat, as assessed by computed tomography scanning, were related to basal and postchallenge insulin in simple correlation analysis, only subcutaneous abdominal fat was independently and positively related to insulin area (among African-American children) after adjusting for total fat; neither index of abdominal fat was independently and positively related to basal and 30 min insulin. These results indicate that, before puberty, total and abdominal subcutaneous fat are more closely related to insulin production and action than is visceral fat.
    • (1998) Am J Clin Nutr , vol.67 , pp. 821-827
    • Gower, B.A.1    Nagy, T.R.2    Trowbridge, C.A.3    Dezenberg, C.4    Goran, M.I.5
  • 14
    • 0028921903 scopus 로고
    • Intra-abdominal adipose tissue in young children
    • Goran MI, Kaskoun MC, Shuman WP. Intra-abdominal adipose tissue in young children. Int J Obes 1995; 19:279-283. This was one of the first studies to document visceral fat by computed tomography scanning in children as young as 6 years of age and show a positive relationship with general body fatness.
    • (1995) Int J Obes , vol.19 , pp. 279-283
    • Goran, M.I.1    Kaskoun, M.C.2    Shuman, W.P.3
  • 15
    • 0030946655 scopus 로고    scopus 로고
    • Visceral fat in Caucasian and African-American pre-pubertal children
    • Goran MI, Nagy TR, Treuth MT, Trowbridge C, Dezenberg C, McGloin A, et al. Visceral fat in Caucasian and African-American pre-pubertal children. Am J Clin Nutr 1997; 65:1703-1709. In this study of 101 African American and Caucasian obese and non-obese pre-pubertal children, visceral fat (by computed tomography scanning) was highly variable and not related to percent body fat, though highly correlated with absolute fat mass and subcutaneous abdominal fat. Visceral fat relative to subcutaneous abdominal fat, was lower in African American than in Caucasian children but was similar in boys and girls.
    • (1997) Am J Clin Nutr , vol.65 , pp. 1703-1709
    • Goran, M.I.1    Nagy, T.R.2    Treuth, M.T.3    Trowbridge, C.4    Dezenberg, C.5    McGloin, A.6
  • 16
    • 0026656504 scopus 로고
    • Body fat distribution in pubertal girls quantified by magnetic resonance imaging
    • de Ridder CM, de Boer RW, Seidell JC, Nieuwenhoff CM, Jeneson JAL, Bakker CJG, et al. Body fat distribution in pubertal girls quantified by magnetic resonance imaging. Int J Obesity 1992; 16:443-449. This was one of the first studies to document visceral fat (using MRI) in healthy, non-obese adolescents.
    • (1992) Int J Obesity , vol.16 , pp. 443-449
    • De Ridder, C.M.1    De Boer, R.W.2    Seidell, J.C.3    Nieuwenhoff, C.M.4    Jeneson, J.A.L.5    Bakker, C.J.G.6
  • 17
    • 0027413685 scopus 로고
    • Abdominal fat deposition in 11-year-old children
    • Fox K, Peters D, Armstrong N, Sharpe P, Bell M. Abdominal fat deposition in 11-year-old children. Int J Obesity 1993; 17:11-16. This was one of the first studies to document visceral fat (using MRI) in healthy, non-obese adolescents. Visceral fat accumulation was not related to general adiposity and was significantly greater among girls.
    • (1993) Int J Obesity , vol.17 , pp. 11-16
    • Fox, K.1    Peters, D.2    Armstrong, N.3    Sharpe, P.4    Bell, M.5
  • 18
    • 0027438143 scopus 로고
    • Sex differences in the relation of visceral adipose tissue accumulation to total body fatness
    • Lemieux S, Prud'homme D, Bouchard C, Tremblay A, Després J-P. Sex differences in the relation of visceral adipose tissue accumulation to total body fatness. Am J Clin Nutr 1993; 58:463-467.
    • (1993) Am J Clin Nutr , vol.58 , pp. 463-467
    • Lemieux, S.1    Prud'Homme, D.2    Bouchard, C.3    Tremblay, A.4    Després, J.-P.5
  • 19
    • 0028037039 scopus 로고
    • Relation of percentage of body fat and maximal aerobic capacity to risk factors for atherosclerosis and diabetes in black and white seven- to eleven-year-old children
    • Gutin B, Islam S, Manos T, Cucuzzo N, Smith C, Stachura ME. Relation of percentage of body fat and maximal aerobic capacity to risk factors for atherosclerosis and diabetes in black and white seven- to eleven-year-old children. J Pediatrics 1994; 125:847-852.
    • (1994) J Pediatrics , vol.125 , pp. 847-852
    • Gutin, B.1    Islam, S.2    Manos, T.3    Cucuzzo, N.4    Smith, C.5    Stachura, M.E.6
  • 20
    • 0024604127 scopus 로고
    • Relationship of body fat distribution to metabolic complications in obese pre-pubertal boys: Gender related differences
    • Legido A, Sarria A, Bueno J, Garagorri J, Fleta J, Ramos F, et al. Relationship of body fat distribution to metabolic complications in obese pre-pubertal boys: gender related differences. Acta Pediatr Scand 1989; 78:440-446.
    • (1989) Acta Pediatr Scand , vol.78 , pp. 440-446
    • Legido, A.1    Sarria, A.2    Bueno, J.3    Garagorri, J.4    Fleta, J.5    Ramos, F.6
  • 21
    • 0028213750 scopus 로고
    • Early changes in postprandial insulin secretion, not in insulin sensitivity, characterize juvenile obesity
    • Le Stunff C, Bougnères P. Early changes in postprandial insulin secretion, not in insulin sensitivity, characterize juvenile obesity. Diabetes 1994; 43:696-702.
    • (1994) Diabetes , vol.43 , pp. 696-702
    • Le Stunff, C.1    Bougnères, P.2
  • 22
    • 0029011340 scopus 로고
    • Insulin regulation of glucose turnover and lipid levels in obese children with fasting normoinsulinaemia
    • Monti LD, Brambilla P, Stefani I, Caumo A, Magni F, Poma R, et al. Insulin regulation of glucose turnover and lipid levels in obese children with fasting normoinsulinaemia. Diabetologia 1995; 38:739-747.
    • (1995) Diabetologia , vol.38 , pp. 739-747
    • Monti, L.D.1    Brambilla, P.2    Stefani, I.3    Caumo, A.4    Magni, F.5    Poma, R.6
  • 23
    • 0030009853 scopus 로고    scopus 로고
    • Glucose effectiveness, peripheral and hepatic insulin sensitivity, in obese and lean pre-pubertal children
    • Hoffman RP, Armstrong PT. Glucose effectiveness, peripheral and hepatic insulin sensitivity, in obese and lean pre-pubertal children. Int J Obesity 1996; 20:521-525.
    • (1996) Int J Obesity , vol.20 , pp. 521-525
    • Hoffman, R.P.1    Armstrong, P.T.2
  • 24
    • 0029828123 scopus 로고    scopus 로고
    • Differences in body composition of black and white girls
    • Yanovski JA, Yanovski SZ, Filmer KM, Hubbard VS, Avila N, Lewis B, et al. Differences in body composition of black and white girls. Am J Clin Nutr 1996; 64:833-839. This study examined the relationships between abdominal fat (by MRI) and metabolic risk factors in normal-weight Caucasian and African-American girls matched for chronological age, bone age, body weight, body mass index. Tanner stage (1-2), and socioeconomic status. Visceral fat was not associated with insulin or lipid parameters in either group, whereas subcutaneous abdominal fat was associated with both basal and 2 h insulin among African-American, but not Caucasian, girls. These results indicate an ethnic difference in the relationship between abdominal fat and metabolic risk, and suggest that subcutaneous, rather than visceral, abdominal fat is associated with basal and postchallenge insulin in young females.
    • (1996) Am J Clin Nutr , vol.64 , pp. 833-839
    • Yanovski, J.A.1    Yanovski, S.Z.2    Filmer, K.M.3    Hubbard, V.S.4    Avila, N.5    Lewis, B.6
  • 25
    • 0024371256 scopus 로고
    • Indices of body fat distribution and adiposity in Dutch children from birth to 18 years of age
    • Weststrate JA, Deurenberg P, van Tinteren H. Indices of body fat distribution and adiposity in Dutch children from birth to 18 years of age. Int J Obesity 1989; 13:465-4677.
    • (1989) Int J Obesity , vol.13 , pp. 465-4677
    • Weststrate, J.A.1    Deurenberg, P.2    Van Tinteren, H.3
  • 26
    • 0025333951 scopus 로고
    • Influence of body fat distribution during childhood on body fat distribution in adulthood: A two decade follow-up study
    • Rolland-Cachera M, Bellisle F, Deheeger M, Pequignot F, Sempe M. Influence of body fat distribution during childhood on body fat distribution in adulthood: a two decade follow-up study. Int J Obesity 1990; 14:473-481.
    • (1990) Int J Obesity , vol.14 , pp. 473-481
    • Rolland-Cachera, M.1    Bellisle, F.2    Deheeger, M.3    Pequignot, F.4    Sempe, M.5
  • 28
    • 0027327339 scopus 로고
    • Association among serum lipid and lipoprotein concentrations and physical activity, physical fitness, and body composition in young children
    • Durant RH, Baranowski T, Rhodes T, Gutin B, Thompson WO, Carroll R, et al. Association among serum lipid and lipoprotein concentrations and physical activity, physical fitness, and body composition in young children. J Pediatrics 1993; 123:185-192.
    • (1993) J Pediatrics , vol.123 , pp. 185-192
    • Durant, R.H.1    Baranowski, T.2    Rhodes, T.3    Gutin, B.4    Thompson, W.O.5    Carroll, R.6
  • 29
    • 0024442241 scopus 로고
    • Relation of body fat patterning to lipid and lipoprotein concentrations in children and adolescents: The Bogalusa Heart Study
    • Freedman DS, Srinivasan SR, Harsha DW, Webber LS, Berenson GS. Relation of body fat patterning to lipid and lipoprotein concentrations in children and adolescents: the Bogalusa Heart Study. Am J Clin Nutr 1989; 50:930-939.
    • (1989) Am J Clin Nutr , vol.50 , pp. 930-939
    • Freedman, D.S.1    Srinivasan, S.R.2    Harsha, D.W.3    Webber, L.S.4    Berenson, G.S.5
  • 32
    • 0025812647 scopus 로고
    • Implications of obesity for cardiovascular disease in blacks: The CARDIA and ARIC studies
    • Folsom AR, Burke GL, Byers CL, Hutchinson RG, Heiss G, Flack JM, et al. Implications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies. Am J Clin Nutr 1991; 53:16043-16113.
    • (1991) Am J Clin Nutr , vol.53 , pp. 16043-16113
    • Folsom, A.R.1    Burke, G.L.2    Byers, C.L.3    Hutchinson, R.G.4    Heiss, G.5    Flack, J.M.6
  • 33
    • 0027408650 scopus 로고
    • Race-dependent health risks of upper body obesity
    • Dowling HJ, Pi-Sunyer FX. Race-dependent health risks of upper body obesity. Diabetes 1993; 42:537-543.
    • (1993) Diabetes , vol.42 , pp. 537-543
    • Dowling, H.J.1    Pi-Sunyer, F.X.2
  • 34
    • 0029761802 scopus 로고    scopus 로고
    • Abdominal fat distribution and metabolic risk factors: Effects of race
    • Lovejoy JC, de la Bretonne JA, Klemperer M, Tulley R. Abdominal fat distribution and metabolic risk factors: effects of race. Metabolism 1996; 45:1119-1124.
    • (1996) Metabolism , vol.45 , pp. 1119-1124
    • Lovejoy, J.C.1    De La Bretonne, J.A.2    Klemperer, M.3    Tulley, R.4
  • 35
    • 0031040841 scopus 로고    scopus 로고
    • Visceral fat and race-dependent health risks in obese non-diabetic pre-menopausal women
    • Albu JB, Murphy L, Frager DH, Johnson JA, Pi-Sunyer FX. Visceral fat and race-dependent health risks in obese non-diabetic pre-menopausal women. Diabetes 1997; 46:456-462.
    • (1997) Diabetes , vol.46 , pp. 456-462
    • Albu, J.B.1    Murphy, L.2    Frager, D.H.3    Johnson, J.A.4    Pi-Sunyer, F.X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.