Advances in schistosomiasis research

Current Opinion in Infectious Diseases

Volumn 11, Issue 5, 1998, Pages 541-546

  Yazdanbakhsh, Maria ^a   Deelder, André M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; PRAZIQUANTEL; SCHISTOSOMA VACCINE;

CHEMOTHERAPY; DISEASE COURSE; FEMALE GENITAL TRACT INFECTION; GRANULOMA; HELMINTHIASIS; HELPER CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNITY; INFECTION RESISTANCE; MICROBIAL GENETICS; MORBIDITY; PATHOLOGY; REVIEW; SCHISTOSOMA HEMATOBIUM; SCHISTOSOMIASIS; T LYMPHOCYTE;

EID: 0031740130     PISSN: 09517375     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001432-199810000-00005     Document Type: Review

References (54)

1. Valli LCP, Kanamura HY, Da Silva RM, Silva MIPG, Vellosa SAG, Garcia ET. Efficacy of an enzyme-linked immunosorbent assay in the diagnosis of and serologic distinction between acute and chronic Schistosoma mansoni infection. Am J Trop Med Hyg 1997; 57:358-362.
2. Li Y, Ross AG, Li Y, He YK, Luo XS, McManus DP. Serological diagnosis of Schistosoma japonicum infections in China. Trans R Soc Trop Med Hyg 1997; 91:19-21.
3. Ramzy RMR, Faris R, Bahgat M, Helmy H, Franklin C, McKerrow JH. Evaluation of a stage-specific proteolytic enzyme of Schistosoma mansoni as a marker of exposure. Am J Trop Med Hyg 1997; 56:668-673. An interesting study that describes the detection of antibodies against a defined antigen (elastase) as a marker for exposure.
4. De Vlas S, Gryseels B, Van Oortmarssen GJ, Polderman AM, Habbema JDF. A pocket chart to estimate true Schistosoma mansoni prevalences. Parasitol Today 1993; 9:305-306.
5. De Vlas SJ, Engels D, Rabello ALT, Oostburg BFJ, Van Lieshout L, Polderman AM et al. Validation of a chart to estimate true Schistosoma mansoni prevalences from simple egg counts. Parasitology 1997; 114:113-121. An important study that provides corroborating evidence for the use of a simple pocket chart to estimate true S. mansoni prevalences.
6. Van Etten L, Engels D, Krijger FW, Nkulikyinka L, Gryseels B, Deelder AM. Fluctuation of schistosome circulating antigen levels in urine of individuals with Schistosoma mansoni infection in Burundi. Am J Trop Med Hyg 1996; 54:348-351.
7. Disch J, Garcia MMA, Krijger FW, Amorim MN, Katz N, Deelder AM et al. Daily fluctuation of levels of circulating cathodic antigen in urine of children infected with Schistosoma mansoni in Brazil. Trans R Soc Trop Med Hyg 1997; 91:222-225.
8. Polman K, Engels D, Fathers L, Deelder AM, Gryseels B. Day-to-day fluctuation of schistosome circulating antigen levels in serum and urine of humans infected with Schistosoma mansoni in Burundi. Am J Trop Med Hyg 1998; 59:150-154. The first detailed analysis of fluctuations of two major circulating antigens in serum and urine in comparison to egg output fluctuation.
9. Van Etten L, Van Lieshout L, Mansour MM, Deelder AM. A reagent strip antigen capture assay for the assessment of cure of schistosomiasis patients. Trans R Soc Trop Med Hyg 1997; 91:154-155.
10. Bosompen KM, Ayi I, Anyan WK, Arishima T, Nkrumah FK, Kojima S. A monoclonal antibody-based dipstick assay for diagnosis of urinary schistosomiasis. Trans R Soc Trop Med Hyg 1997; 91:554-556.
11. Stelma FF, Sall S, Daff B, Sow S, Niang M, Gryseels B. Oxamniquine cures Schistosoma mansoni infection in a focus in which cure rates with Praziquantel are unusually low. J Infect Dis 1997; 176:304-307.
12. Guissé F, Polman K, Stelma FF, Mbaye A, Talla I, Niang M et al. Therapeutic evaluation of two different dose regimens of praziquantel in a recent Schistosoma mansoni focus in northern Senegal. Am J Trop Med Hyg 1997; 56:511-514.
13. Fallon PG, Mubarak JS, Fookes RE, Niang M, Butterworth AE, Sturrocks RF, Doenhoff MJ. Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates. Exp Parasitol 1997; 86:29-36.
14. Picquet M, Vercruysse J, Shaw DJ, Diop M, Ly A. Efficacy of praziquantel against Schistosoma mansoni in northern Senegal. Trans R Soc Trop Med Hyg 1998; 92:90-93.
15. Bennett JL, Day T, Feng-Tao L, Ismail M, Farghaly A. The development of resistance to anthelmintics: a perspective with an emphasis on the antischistosomal drug praziquantel. Exp Parasitol 1997; 87:260-267.
16. Helling-Giese G, Kjetland EF, Gundersen SG, Poggensee G, Richter J, Krantz I, Feldmeier H. Schistosomiasis in women: manifestations in the upper reproductive tract. Acta Tropica 1996; 62:225-238.
17. Kjetland EF, Poggensee G, Helling-Giese G, Richter J, Sjaastad A, Chitsulo L et al. Female genital schistosomiasis due to Schistosoma haematobium. Clinical and parasitological findings in women in rural Malawi. Acta Tropica 1996; 62:239-255.
18. Richter J, Poggensee G, Kjetland EF, Helling-Giese G, Chitsulo L, Kumwenda N et al. Reversibility of lower reproductive tract abnormalities in women with Schistosoma haematobium infection after treatment with praziquantel - an interim report. Acta Tropica 1996; 62:289-301.
19. Leutscher P, Raharisolo C, Pecarrere JL, Ravaoalimalala VE, Serieye J, Rasendramino M et al. Schistosoma haematobium induced lesions in the female genital tract in a village in Madagascar. Acta Tropica 1997; 66:27-33.
20. Vilana R, Corachan M, Gascon J, Valls E, Bru C. Schistosomiasis of the male genital tract: transrectal sonographic findings. J Urology 1997; 158:1491-1493.
21. Marquet S, Abel L, Hillaire D, Dessein H, Kalil J, Feingold J et al. Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nat Genet 1996; 14:181-184.
22. Müller-Myhsok B, Stelma FF, Guissé-Sow F, Muntau B, Thye T, Burchard GD et al. Further evidence suggesting the presence of a locus, on human chromosome 5q31-q33, influencing the intensity of infection with Schistosoma mansoni. Am J Hum Genet 1997; 61:452-454. An excellent report on the search for gene(s) involved in controlling infection with S. mansoni. The replication of the finding that SM1 is localized on chromosome 5.
23. El-Ridi R, Farouk F, Sherif M, Al-Sherbiny M, Osman A, El Gengehi N, Shoemaker CB. T and B cell reactivity to a 42-kDa protein is associated with human resistance to both Schistosoma mansoni and haematobium. J Infect Dis 1998; 177:1364-1372. A comprehensive effort has been made to identify schistosome antigens recognized by individuals resistant to either infection or reinfection.
24. Goudot-Crozel V, Caillol D, Djabali M, Dessein AJ. The major parasite surface antigen associated with human resistance to schistosomiasis is a 37-kD glyceraldehyde-3P-dehydrogenase. J Exp Med 1998; 170:2065-2080.
25. Waine GJ, Yang W, Ross AG, Li YS, Sleigh AC, Kalinna BH et al. Differential antigen-stimulated proliferation of human mononuclear cells by recombinant Schistosoma japonicum antigens in a Chinese population. Clin Exp Immunol 1998; 112:69-73.
26. Hirsch C, Almeida CA, Doughty BL, Goes AM. Characterization of Schistosoma mansoni 44.7/56.8 kDa egg antigens recognized by human monoclonal antibodies which induce protection against experimental infection and proliferation of peripheral blood mononuclear cells from schistosomiasis patients. Vaccine 1997; 15:948-954.
27. Zhaosong Z, Haiwei W, Suchen C, Lingshen H, Zhangwu X, Yingxi Q et al. Association between IgE antibody against soluble egg antigen and resistance to reinfection with Schistosoma japonicum. Trans R Soc Trop Med Hyg 1997; 91:606-608.
28. Webster M, Libranda-Ramirez BDL, Aligui GD, Olveda RM, Ouma JH, Kariuki HC et al. The influence of sex and age on antibody isotype responses to Schistosoma mansoni and Schistosoma japonicum in human populations in Kenya and the Philippines. Parasitology 1997; 114:383-393.
29. Webster M, Correa-Oliveira R, Gazzinelli G, Viana IRC, Alves de Oliveira Fraga L, Soares Silveira AM, Dunne DW. Factors affecting high and low human IgE responses to schistosome worm antigens in an area of Brazil endemic for Schistosoma mansoni and hookworm. Am J Trop Med Hyg 1997; 57:487-494.
30. + T cell-mediated granulomatous pathology in schistosomiasis is downregulated by a B-cell-dependent mechanism requiring Fc receptor signaling. J Exp Med 1998; 187:619-629. This is a comprehensive study of granuloma formation in μMT B-cell-deficient mice showing that B cells are essential for the downmodulation of granuloma formation during the chronic phase of infection. Signalling via FcγR appears to be necessary for this process.
31. Jankovic D, Kullberg MC, Dombrowicz D, Barbieri S, Caspar P, Wynn TA et al. Fc epsilonRI-deficient mice infected with Schistosoma mansoni mount normal Th2-type responses while displaying enhanced liver pathology. J Immunol 1997; 159:1868-1875.
32. El Ridi R, Ozaki T, Kamiya H. Schistosoma mansoni infection in IgE-producing and IgE-deficient mice. J Parasitol 1998; 84:171-174.
33. King CL, Xianli J, Malhotra I, Liu S, Mahmoud AA, Oettgen HC. Mice with a targeted deletion of the IgE gene have increased worm burdens and reduced granulomatous inflammation following primary infection with Schistosoma mansoni. J Immunol 1997; 158:294-300.
34. Oswald IP, Caspar P, Wynn TA, Scharton-Kersten T, Williams ME, Hieny S et al. Failure of P strain mice to respond to vaccination against schistosomiasis correlates with impaired production of IL-12 and upregulation of Th2 cytokines that inhibit macrophage activation. Eur J Immunol 1998; 28:1762-1772.
35. Coulson PS, Smythies LE, Betts C, Mabbott NA, Sternberg JM, Wei XG et al. Nitric oxide produced in the lungs of mice immunized with the radiation-attenuated schistosome vaccine is not the major agent causing challenge parasite elimination. Immunology 1998; 93:55-63.
36. Ottesen EA. Modulation of the host response in human schistosomiasis. I. Adherent suppressor cells that inhibit lymphocyte proliferative responses to parasite antigens. J Immunol 1979; 123:1639-1644.
37. Gazzinelli G, Montesano MA, Correa-Oliveira R, Lima MS, Katz N, Rocha RS, Colley DG. Immune response in different clinical groups of schistosomiasis patients. Mem Inst Oswaldo Cruz 1987; 82:95-100.
38. + cells after chemotherapy in human Schistosoma haematobium infection. Eur J Immunol 1996; 26:1365-1370.
39. Grogan JL, Kremsner PG, Deelder AM, Yazdanbakhsh M. Antigen-specific proliferation and interferon-gamma and interleukin-5 production are down-regulated during Schistosoma haematobium infection. J Infect Dis 1998; 177:1433-1437. A study of human S. haematobium infection that provides data on the relationship between proliferation and cytokine production by T cells and active infection encompassing resistance and susceptibility to reinfection.
40. Malaquias LCC, Falcao PL, Silveira AMS, Gazzinelli G, Prata A, Coffman RL et al. Cytokine regulation of human immune response to Schistosoma mansoni: analysis of the role of IL-4, IL-5 and IL-10 on peripheral blood mononuclear cell responses. Scand J Immunol 1997; 46:393-398.
41. Rezende SA, Lambertucci JR, Goes AM. Role of immune complexes from patients with different clinical forms of schistosomiasis in the modulation of in vitro granuloma research. Mem Inst Oswaldo Cruz 1997; 92:683-687.
42. King CL, Malhotra I, Mungai P, Wamachi A, Kioko J, Ouma JH, Kazura JW. B cell sensitization to helminthic infection develops in utero in humans. J Immunol 1998; 160:3578-3584.
43. + cells in human schistosomiasis. Here the authors show that an intact immune system is required for egg excretion.
44. Jacobs W, Bogers J, Deelder A, Wéry M, Van Marck E. Adult Schistosoma mansoni worms positively modulate soluble egg antigen-induced inflammatory hepatic granuloma formation in vivo. Stereological analysis and immuno-phenotyping of extracellular matrix proteins, adhesion molecules, and chemokines. Am J Pathol 1997; 150:2033-2045.
45. Hirsch C, Zouain CS, Alves JB, Goes AM. Induction of protective immunity and modulation of granulomatous hypersensitivity in mice using PIII, an anionic fraction of Schistosoma mansoni adult worm. Parasitology 1997; 115:21-28.
46. Hernandez HJ, Wang Y, Tzellas N, Stadecker MJ. Expression of class II, but not class I, major histocompatibility complex molecules is required for granuloma formation in infection with Schistosoma mansoni. Eur J Immunol 1997; 27:1170-1176. Carefully designed experiments to delineate the role of class I and class II presentation pathways in regulating granuloma formation. A clear and comprehensive discussion is presented.
47. Wynn TA, Morawetz R, Scharton-Kersten T, Hieny S, Morse III HC, Kuhn R et al. Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1-and T helper cell 2-type cytokine responses in vivo. J Immunol 1997; 159:5014-5023.
48. Subramanian G, Kazura JW, Pearlman E, Jia X, Malhotra I, King CL. B7-2 requirement for helminth-induced granuloma formation and CD4 type 2 T helper cell cytokine expression. J Immunol 1997; 158:5914-5920.
49. Pearce EJ, Cheever A, Leonard S, Covalesky M, Fernandez-Botran R, Kohler G, Kopf M. Schistosoma mansoni in IL-4 deficient mice. Int Immunol 1996; 8:435-444.
50. Brunet LR, Finkelman FD, Cheever AW, Kopf MA, Pearce EJ. IL-4 protects against TNF-alpha-mediated cachexia and death during acute schistosomiasis. J Immunol 1997; 159:777-785. A very important contribution to the field. The importance of looking at infection as a whole rather than focusing on a narrow window of time is highlighted in this study.
51. Mwatha JK, Kimani G, Kamau T, Mbugua GG, Ouma JH, Mumo J et al. High levels of TNF, soluble TNF receptors, soluble ICAM-1, and IFN-γ, but low levels of IL-5, are associated with hepatosplenic disease in human Schistosoma mansoni. J Immunol 1998; 160:1992-1999. The findings in mice that IL-4 and anti-inflammatory cytokines are important in containing severe pathological outcome of schistosome infection is clearly relevant to studies in humans, as shown in this paper.
52. Wynn TA, Cheever AW, Williams ME, Hieny S, Caspar P, Kuhn R et al. IL-10 regulates liver pathology in acute murine Schistosoma mansoni but is not required for immune down-modulation of chronic disease. J Immunol 1998; 160:4473-4480. This paper demonstrates the importance of IL-10 in vivo by using IL-10 gene knockout mice.
53. Flores-Villanueva PO, Zheng XX, Strom TB, Stadecker MJ. Recombinant IL-10 and IL-10/Fc treatment down-regulate egg antigen-specific delayed hypersensitivity reactions and egg granuloma formation in schistosomiasis. J Immunol 1996; 156:3315-3320.
54. Hernandez HJ, Wang Y, Stadecker MJ. In infection with Schistosoma mansoni, B cells are required for T helper type 2 cell responses but not for granuloma formation. J Immunol 1997; 158:4832-4837.