Statistical methods for evaluating multiple sclerosis therapies

Seminars in Neurology

Volumn 18, Issue 3, 1998, Pages 351-375

  Petkau, John ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Clinical trials; Confidence intervals; Hypothesis testing

Indexed keywords

CLINICAL RESEARCH; COVARIANCE; DATA ANALYSIS; HUMAN; HYPOTHESIS; MATHEMATICAL COMPUTING; METHODOLOGY; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; REVIEW; STATISTICAL ANALYSIS; SURVIVAL;

EID: 0031739263     PISSN: 02718235     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1040886     Document Type: Review

References (36)

1. Matthews DE, Farewell V. Using and understanding medical statistics. Basel: Karger, 1985
2. Armitage P, Berry G. Statistical methods in medical research, 2nd ed. Oxford: Blackwell, 1987
3. Altman DG. Practical statistics for medical research. London: Chapman and Hall, 1991
4. The IFNB Multiple Sclerosis Group. Interferon β-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 1993;43:655-661
5. Paty DW, Li DKB, the UBC MS/MRI Study Group, the IFNB Multiple Sclerosis Group. Interferon β-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 1993;43:662-667
6. Mehta CR. StatXact: A statistical package for exact nonparametric inference. Am Stat 1991;45:74-75
7. Edgington ES. Randomization tests, 2nd ed. New York: Dekker, 1987
8. Machin D, Campbell MJ. Statistical tables for the design of clinical trials. Oxford: Blackwell, 1987
9. Efron B. Bootstrap methods: another look at the jackknife. Ann Stat 1979;7:1-26
10. Diaconis P, Efron B. Computer-intensive methods in statistics. Sci Am 1983;248:116-130
11. Efron B, Tibshirani RJ. Statistical data analysis in the computer age. Science 1991,253.390-395
12. Efron B, Tibshirani RJ. An introduction to the bootstrap. New York: Chapman and Hall, 1993
13. Schlesselman JJ. Case-control studies: Design, conduct, analysis. Oxford: University Press, 1982
14. Kalbfleisch JD, Prentice RL. The statistical analysis of failure time data. New York: Wiley, 1980
15. Lawless JF. Statistical models and methods for lifetime data. New York: Wiley, 1982
16. Lee ET. Statistical methods for survival data analysis. New York: Wiley, 1992
17. Collett D. Modelling survival data in medical research. London: Chapman and Hall, 1994
18. Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer 1976;34:585-612
19. Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer 1977;35:1-39
20. Gehan EA. A generalized Wilcoxon test for comparing arbitrarily singly-censored samples. Biometrika 1965;52:203-223
21. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Nat Cancer Inst 1959; 22:719-748
22. Petkau J. Statistical and design considerations for multiple sclerosis clinical trials. In: Goodkin DE, Rudick RA, eds. Multiple sclerosis: Advances in clinical trial design, treatment and future perspectives. London: Springer, 1996:63-103
23. Cox DR. Regression models and life tables [with discussion]. J R Stat Soc Ser B 1972;74:187-220
24. Tibshirani R. A plain man's guide to the proportional hazards model. Clin Invest Med 1982;5:63-68
25. Koch GG, Amara IA, Davis GW, Gillings DB. A review of some statistical methods for covariance analysis of categorical data. Biometrics 1982;38:563-595
26. Altman DG. Comparability of randomized groups. The Statistician 1985;34:125-136
27. Senn SJ. Covariate imbalance and random allocation in clinical trials. Stat Med 1989;8:467-475
28. Frison L, Pocock SJ. Repeated measures in clinical trials: analysis using mean summary statistics and its implications for design. Stat Med 1992;11:1685-1704
29. Zeger SL, Liang KY. An overview of methods for the analysis of longitudinal data. Stat Med 1992;11:1825-1839
30. Liang KY, Zeger SL. Regression analysis for correlated data. Ann Rev Public Health 1993;14:43-68
31. D'yachkova Y, Petkau J, White R. Longitudinal analyses for magnetic resonance imaging outcomes in multiple sclerosis clinical trials. J Biopharm Stat 1997;7:501-531
32. Laird NM, Ware JH. Random-effects models for longitudinal data. Biometrics 1982;38:963-974
33. Gibbons RD, Hedeker D, Elkin I. et al. Some conceptual and statistical issues in analysis of longitudinal psychiatric data. Arch Gen Psych 1993;50:739-750
34. Diggle PJ, Liang KY, Zeger SL. Analysis of longitudinal data. Oxford: Clarendon Press, 1994
35. Hand DJ, Crowder MJ. Practical longitudinal data analysis. London: Chapman and Hall, 1996
36. Petkau J, White R. Neutralizing antibodies and the efficacy of interferon β-1b in relapsing-remitting multiple sclerosis. Biostatistics Research Report #12, Biostatistics Research Group, University of British Columbia, 1997