Cross reacting antibodies against keyhole limpet haemocyanin may interfere with the diagnostics of acute schistosomiasis

Parasite Immunology

Volumn 20, Issue 10, 1998, Pages 489-496

  Thors, Cecilia ^a   Linder, Ewert ^a  

^a SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

Author keywords

Cross reactions; Immunodiagnostics; Invasive worm infections; Keyhole limpet haemocyanin; Schistosoma; Serology; Travel medicine

Indexed keywords

CROSS REACTING ANTIBODY; KEYHOLE LIMPET HEMOCYANIN;

ANTIBODY RESPONSE; ARTICLE; CROSS REACTION; EGG PRODUCTION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOGENICITY; NONHUMAN; PRIORITY JOURNAL; SCHISTOSOMIASIS; SERODIAGNOSIS; TRICHINOSIS;

AGE FACTORS; ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; CROSS REACTIONS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HEMOCYANIN; HUMANS; IMMUNOBLOTTING; MALE; MICE; SCHISTOSOMA; SCHISTOSOMIASIS; SEROLOGIC TESTS; SNAILS; TRAVEL;

SCHISTOSOMA; TREMATODA;

EID: 0031738625     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.1998.00185.x     Document Type: Article

References (38)

1. Capron A., Pierce R., Balloul J., Grzych J.M., Dissous C., Sondermeyer P. & Lecocq J.P. (1987) Protective antigens in experimental schistosomiasis. Acta Tropica (Supplement) 12, 63-69
2. Cen L.P., Viana L.G., Garcia T.C.M., Rabello A.L.T. & Katz N. (1996) The serological differentiation of acute and chronic schistosomiasis japonica using IgA antibody to egg antigen. Memorias do Instituto Oswaldo Cruz 91, 751-754
3. Cetron M.S., Chitsulo L., Sullivan J.J. et al. (1996) Schistosomiasis in Lake Malawi. Lancet 348, 1274-1278
4. Coker C.M. & von Lichtenberg F. (1956) A revised method for isolation of Schistosama mansoni eggs for biological experimentation. Proceedings of the Society of Experimental Biological Medicine 92, 780-782
5. Deelder A.M. & Kornelis D. (1981) Immunodiagnosis of recently acquired Schistosoma mansoni infection. A comparison of various immunological techniques. Tropical and Geographical Medicine 33, 36-41
6. El-Morshedy H., Kinosien B., Barakat R., Orner E., Khamis N., Deelder A.M. & Phillips M. (1996) Circulating anodic antigen tor detection of Schistosoma mansoni infection in Egyptian patients. American Journal of Tropical Medicine and Hygiene 54, 149-153
7. Evengård B., Hammarström L., Smith C.I.E. & Linder R. (1990) Early antibody responses in human schistosomiasis. Clinical Experimental Immunology 80, 69-76
8. Feldmeier, H. & Poggensee G. (1993) Diagnostic techniques in schistosomiasis control. A review. Acta Tropica (Basel) 52, 205-220
9. Grzrych J.-M., Dissous C., Capron M., Torres S., Lambert, P-H. & Capron A. (1987) Schistosoma mansoni shares a protective carbohydrate epitope with keyhole limpet hemocyanin. Journal of Experimental Medicine 165, 865-878
10. Hancock K. & Tsang V.C.W. (1986) Development and optimization of the FAST-ELISA for detecting antibodies to Schistosoma mansoni. Journal of Immunological Methods 92, 167-176
11. Houpis J., Oexmann J., Martin J., Jacobi G., Reardon J. & Waterman G. (1984) Acute schistosomiasis with transverse myelitis in American students returning from Kenya. MMWR - Morbidity & Mortality Weekly Report 33, 445-447
12. Istre G.R., Fontaine R.E., Tarr J. & Hopkins R.S. (1984) Acute schistosomiasis among Americans rafting the Omo River, Ethiopia. Jama 251, 508-510
13. Junghanss T. & Weiss N. (1992) Acute schistosomiasis in travellers to the tropics. Deutsche Medizinische Wochenschrift 117, 935-940
14. Li Y., Rabello A.L., Simpson A.J. & Katz N. (1994) The serological differentiation of acute and chronic Schistosoma japonicum infection by ELISA using keyhole limpet haemocyanin as antigen. Transactions of the Royal Society of Tropical Medicine and Hygiene 88, 249-251
15. Linder E., Thors C. & Lundin L. (1991) Isolation of an SBA lectin-reactive glycoprotein (gp50) and its identification in Schistosoma mansoni larval and adult worm secretions. Journal of Parasitology 77, 391-401
16. Linder E., Thors C., Lundin L., Ljungström I., Farah S., Hagi H. & Dias F. (1992) Schistosome antigen gp50 is responsible for serological cross-reactivity with Trichinella spiralis. Journal of Parasitology 78, 999-1005
17. Londner M.V., Rosen G., Sintov A. & Spira D.T. (1987) The feasibility of a dot blot enzyme-linked immunosorbent assay (dot-ELISA) for the diagnosis of Plasmodium falciparum antigens and antibodies. American Journal of Tropical Medicine and Hygiene 36, 240-245
18. Mansour M.M., Ali P.O., Fand Z., Simpson A.J. & Woody J.W. (1989) Serological differentiation of acute and chronic schistosomiasis mansoni by antibody responses to keyhole limpet hemocyanin. American Journal of Tropical Medicine and Hygiene 41, 338-344
19. Modha J., Robertson W.M., Kennedy M.W. & Kusel J.R. (1994) Characterization of a major surface-associated excretory-secretory antigen of Trichinella spiralis larvae with antibodies to keyhole limpet haemocyanin. Parasitology 109, 531-538
20. Mott K.E. & Dixon H. (1982) Collaborative study on antigens for immunodiagnosis of Schistosomiasis. Bulletin of the World Health Organization 60, 729-753
21. Nash T.E. (1974) Localization of the circulating antigen within the gut of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 23, 1085-1087
22. Ndhlovu P., Cadman H., Gundersen S. et al. (1996) Circulating anodic antigen (CAA) levels in different age groups in a Zimbabwean rural community endemic for Schistosoma haematobium determined using the magnetic beads antigen-capture enzyme-linked immunoassay. American Journal of Tropical Medicine and Hygiene 54, 537-542
23. Okot-Kotber B.M. (1976) The development of stage-characteristic immunofluorescence patterns in experimental schistosomiasis in mice. Annals of Tropical Medicine and Parasitology 72, 255-262
24. Pitkänen Y.T., Peltonen M., Lähdevirta J., Meri S., Evengård B. & Linder E. (1990) Acute schistosomiasis mansoni in Finnish hunters visiting Africa: need for appropriate diagnostic serology. Scandinavian Journal of Infectious Diseases 22, 597-600
25. Rabello A.L.T., Garcia M.M.A., Pinto da Silva R.A., Rocha R.S. & Katz N. (1997) Humoral responses in patients with acute Schistosoma mansoni infection who were followed up two years after treatment. Clinical Infectious Diseases 24, 304-308
26. Tsang V.C.W. & Wilkins P.P. (1991) Immundiagnosis of schistosomiasis. Clinics in Laboratory Medicine 11, 1029-1039
27. Tsang V.C.W. & Wilkins P.P. (1997) Immundiagnosis of schistosomiasis. Immunological Investigations 26, 175-188
28. Van't Wout A.B., De Jonge N., Wood S.M., Van Lieshout L., Mitchell G.F. & Deelder A.M. (1995) Serum levels of circulating anodic antigen and circulating cathodic antigen detected in mice infected with Schistosoma japonicum or S. mansoni. Parasitology Research 81, 434-437
29. Van Dam G.J., Qian Z.L., Fillie Y.E., Rotmans J.P. & Deelder A.M. (1993) Detection of IgM antibodies directed against the gut-associated circulating cathodic antigen in sera from Schistosoma mansoni infected patients. Development and comparison of three enzyme-linked immunoassays. Tropical and Geographical Medicine 45, 59-65
30. Van Etten L., Engels D., Krijger F.W., Nkulikyinka L., Gryseels B. & Deelder A.M. (1996) Fluctuation of schistosome circulating antigen levels in urine of individuals with Schistosoma mansoni infection in Burundi. American Journal of Tropical Medicine and Hygiene 54, 348-351
31. Van Helden H.P.T., Terpstra W.J., Okot-Kotber B.M. & Eyakuze V.M. (1975) Are there stage-characteristic immunofluorescence patterns in schistosomiasis? Transactions of the Royal Society of Tropical Medicine and Hygiene 69, 309-311
32. Verweij J.J., Polderman A.M., Visser L.G. & Deelder A.M. (1995) Measurement of antibody response to keyhole limpet haemocyanin was not adequate for early diagnosis of schistosomiasis in a group of Dutch visitors to Mali. Transactions of the Royal Society of Tropical Medicine and Hygiene 89, 48-50
33. Von Lichtenberg F., Bawden M.P., Shealey, S.H. (1974) Origin of circulating antigen from the schistosome gut. American Journal of Tropical Medicine and Hygiene 23, 1088-1091
34. Wilson M., Sulzer A.J. & Walls K.W. (1974) Modified antigens in indirect immunofluorescence test for schistosomiasis. American Journal of Tropical Medicine and Hygiene 23, 1072-1076
35. Wirguin I., Suturkova-Milosevic L., Briani C. & Latov N. (1995) Keyhole limpet hemocyanin contains Gal(β 1-3)-GalNAc determinants that are cross-reactive with the T antigen. Cancer Immunology and Immunotherapy 40, 307-310
36. Xue C.G., Taylor M.G., Bicle Q.D., Savioli L. & Renganathan E.A. (1993) Diagnosis of Schistosoma haematobuin infection: evaluation of ELSA using keyhole limpet haemocyanin or soluble egg antigen in comparison with detection of eggs or haematuria. Transactions of the Royal Society of Tropical Medicine and Hygiene 87, 654-658
37. Zheg X.F., Wang S.P., Lai W.Z. & Xiang Y.D. (1992) Studies on the KLH-ELISA and KLH-IHA for the diagnosis of Schistosoma japonicum infection. Chinese Journal of Schistosomiasis Control 4, 57-58
38. Zuidema P.J. (1981) The Katayama syndrome; an outbreak in Dutch tourists to the Omo National Park, Ethiopia. Tropical and Geographical Medicine 33, 30-35