The quantitative determination of cilostazol and its four metabolites in human liver microsomal incubation mixtures by high-performance liquid chromatography

Journal of Pharmaceutical and Biomedical Analysis

Volumn 18, Issue 3, 1998, Pages 441-451

  Tata, Prasad N V ^a   Fu, Chau Hwei J ^b   Browder, Norma J ^a   Chow, Paul C ^a   Bramer, Steven L ^a  

^a OTSUKA PHARMACEUTICAL DEVELOPMENT AND COMMERCIALIZATION INC   (United States)

^b Kansas City Analytical Services   (United States)

Author keywords

Cilostazol; Gradient elution; High performance liquid chromatography; Liver microsomes

Indexed keywords

CILOSTAZOL; DIETHYLDITHIOCARBAMIC ACID; DRUG METABOLITE; FURAFYLLINE; KETOCONAZOLE; OMEPRAZOLE; QUINIDINE SULFATE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CALIBRATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ISOLATION; DRUG LIVER LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIVER MICROSOME; PRIORITY JOURNAL; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STANDARD; VALIDATION PROCESS;

ACETONITRILES; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSOMES, LIVER; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TETRAZOLES; ULTRAVIOLET RAYS;

EID: 0031737598     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(98)00052-1     Document Type: Article

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