Chronic pancreatitis at Manchester, UK. Focus on antioxidant therapy

Digestion

Volumn 59, Issue SUPPL. 4, 1998, Pages 36-48

  McCloy, Rory ^a  

^a MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Antioxidant therapy; Chronic pancreatitis; Free radicals; Methionine; Oxidative stress; Pancreatic surgery; Selenium; Vitamin C

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; GLUTATHIONE; METHIONINE; SELENIUM; XENOBIOTIC AGENT;

CHRONIC PANCREATITIS; CONFERENCE PAPER; HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RISK FACTOR; UNITED KINGDOM; XENOBIOTIC METABOLISM;

ANTIOXIDANTS; ASCORBIC ACID; CHRONIC DISEASE; CROSS-SECTIONAL STUDIES; GREAT BRITAIN; HUMANS; METHIONINE; PANCREATITIS; RANDOMIZED CONTROLLED TRIALS; RETROSPECTIVE STUDIES; RISK FACTORS; SELENIUM;

EID: 0031737255     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000051441     Document Type: Conference Paper

References (55)

1. Trapnell JE: Chronic relapsing pancreatitis: A review of 64 cases. Br J Surg 1979;66:471-475.
2. Moossa A: Surgical treatment of chronic pancreatitis: An overview. Br J Surg 1987;74:661-667.
3. Frey CF: Current management of chronic pancreatitis. Adv Surg 1995;28:337-270.
4. Andren-Sandberg A: Pain relief in pancreatic disease. Br J Surg 1997;84:1041-1042.
5. Ihse I: Pancreatic pain. Br J Surg 1990;77:121-122
6. Worning H: Chronic pancreatitis: Pathogenesis, natural history and conservative treatment. Clin Gastroenterol 1984;3:871-894.
7. Andren-Sandberg A, Zoucas E, Lillo-Gil R, Gyllstedt E, Ihse I: Thoracoscopic splanchnicectomy for chronic, severe pancreatic pain. Semin Laparosc Surg 1996;3:29-33.
8. Beger HG, Buchler M, Ditschuneit H, Malfertheiner P (eds): Chronic Pancreatitis. Heidelberg, Springer, 1990.
9. Walsh TN, Rode J, Theis BA, Russell RCG: Minimal change chronic pancreatitis. Gut 1992;33:1566-1571.
10. Fleming WR, Williamson RC: Role of total pancreatectomy in the treatment of patients with end-stage chronic pancreatitis. Br J Surg 1995;82:1409-1412.
11. Izbicki JR, Bloechle C, Knoefel WT, Kuechler T, Binmoeller KF, Broelsch CE: Duodenumpreserving resection of the head of the pancreas in chronic pancreatitis. A prospective, randomized trial. Ann Surg 1995;221:350-358.
12. Braganza JM: Pancreatic disease: A casualty of hepatic 'detoxification'? Lancet 1983;ii:1000-1003.
13. Braganza JM: The pancreas. Recent Advances in Gastroenterology. London, Churchill-Livingstone, 1986;6:251-280.
14. Braganza JM: The pathogenesis of chronic pancreatitis. Q J Med 1996;89:243-250.
15. Foster JR, Idle JR, Hardwick JP, Bars R, Scott P, Braganza JM: Induction of drug metabolising enzymes in human pancreatic cancer and chronic pancreatitis. J Pathol 1993;169:457-463.
16. Braganza JM, Jolley JE, Lee WR: Occupational volatile chemicals and pancreatitis: A link? Int J Pancreatol 1986;1:9-19.
17. Braganza JM: Toxicology of the pancreas; in Ballantyne B, Turner P, Marrs TC (eds): Textbook of General and Applied Toxicology. New York, MacMillan, 1993, pp 663-714.
18. Stenson WF, Lobos E, Wedner HJ: Glutathione depletion inhibits amylase release in guinea pig pancreatic acini. Am J Physiol 1983; 244:G273-G277.
19. Veghely PV, Kemeny TT: Protein metabolism and pancreatic function; in de Reuck AVS, Cameron MP (eds): Ciba Foundation Symposium on the Exocrine Pancreas. London, J & A Churchill, 1962, pp 329-349.
20. Braganza JM, Chaloner C: Acute pancreatitis. Curr Opin Anaesthesiol 1995;8:126-131.
21. Guyan PM, Uden S, Braganza JM: Heightened free radical activity in pancreatitis. Free Radical Biol Med 1990;8:347-354.
22. Acheson DWK, Hunt LP, Rose P, Houston JB, Braganza JM: Factors contributing to the accelerated clearance of theophylline and antipyrine in adults with exocrine pancreatic disease. Clin Sci 1989;76:377-385.
23. McNamee R, Braganza JM, Hogg J, Leek I, Rose P, Cherry N: Occupational exposure to hydrocarbons and chronic pancreatitis: A case-referent study. Occup Environ Med 1994;51: 631-637.
24. Uden S, Acheson DWK, Reeves J, Worthington HV, Hunt LP, Brown S, Braganza JM: Antioxidants, enzyme induction and chronic pancreatitis: A re-appraisal following studies in patients on anti-convulsants. Eur J Clin Nutr 1988;42:561-569.
25. Sandilands D, Jeffrey IJM, Haboubi NY, MacLennan I, Braganza JM: Abnormal drug metabolism in chronic pancreatitis: Treatment with antioxidants. Gastroenterology 1990;98: 766-772.
26. Braganza JM (ed): The Pathogenesis of Pancreatitis. Manchester, Manchester University Press, 1991.
27. Braganza JM, Thomas A, Robinson A: Antioxidants to treat chronic pancreatitis in childhood? Case report and possible implications for pathogenesis. Int J Pancreatol 1988;3:309-316.
28. Braganza JM, Jeffrey IGM, Foster J, McCloy RF: Recalcitrant pancreatitis: Eventual control by antioxidants. Pancreas 1987;2:489-494.
29. Braganza JM, Hewitt CD, Day JP: Serum selenium in patients with chronic pancreatitis; lowest values during painful exacerbations. Trace Elements Med 1988;5:79-84.
30. Uden S, Bilton D, Nathan L, Hunt LP, Main C, Braganza JM: Antioxidant therapy for recurrent pancreatitis: Placebo-controlled trial. Aliment Pharmacol Ther 1990;4:357-371.
31. Uden S, Schofield G, Miller PF, Day JP, Bottiglieri T, Braganza JM: Antioxidant therapy for recurrent pancreatitis: Biochemical profiles in a placebo-controlled trial. Aliment Pharmacol Ther 1992;6:229-240.
32. Martensson J, Bolin T: Sulfur amino acid metabolism in chronic relapsing pancreatitis. Am J Gastroenterol 1986;81:1179-1184.
33. Bilton D, Schofield D, Mei G, Kay PM, Bottiglieri T, Braganza JM: Placebo-controlled trials of antioxidant therapy including S-adenosulmethionine in patients with recurrent non-gallstone pancreatitis. Drug Invest 1994;8:10-20.
34. Burdick JS, Hogan WJ: Chronic pancreatitis: Selection of patients for endoscopic therapy. Endoscopy 1991;23:155-159.
35. Martin RF, Hanson BL, Bosco JJ, Erkkinen JF, Broaddus SB, Goldfarb WB, Howell DA: Combined modality treatment of symptomatic pancreatic ductal lithiasis. Arch Surg 1995;130: 375-380.
36. Whiteley G, Kienle A, Lee S, Taylor P, Schofield D, Braganza J, McCloy R: Micronutrient antioxidant therapy in the non-surgical management of painful chronic pancreatitis: Long-term observations (abstract). Pancreas 1994;9: A807.
37. Talamani G, Bassi C, Falconi M, Frulloni L, Di Francesco V, Vaona B, Bovo P, Rigo L, Castagnini A, Angelini G, Vantini I, Pederzoli P, Cavallini G: Cigarette smoking: An independent risk factor in alcoholic pancreatitis. Pancreas 1996;12:131-137.
38. Cohen S, Nichols A, Wyatt R: The administration of methionine to chronic schizophrenic patients: A review of 10 studies. Biol Psychiatry 1974;8:209-225.
39. Izbicki JR, Bloechle C, Knoefel WT, Kuechler T, Binmoeller KF, Broelsch CE: Duodenum-preserving resection of the head of the pancreas in chronic pancreatitis. Ann Surg 1995;221: 350-358.
40. Warshaw AL, Banks PA, Fernández-del CastilIo C: AGA technical review: Treatment of pain in chronic pancreatitis. Gastroenterology 1998; 115:765-776.
41. Sharer NM, Taylor PM, Lineker BD, Gutteridge JMC, Braganza JM: Safe and successful use of vitamin C to treat painful calcific chronic pancreatitis despite ion overload from primary haemochromatosis. Clin Drug Invest 1995;10:310-315.
42. Sharer NM, Rameh B, Braganza JM: Control by antioxidant therapy (AOT) of recurrent pancreatitis from type I hyperlipidaemia. Gut 1997;41(suppl. 3):A12.
43. Wang ZH, Iguchi H, Oshio G, Inamura T, Okada N, Tanaka T, Imamura M: Increased pancreatic metallothionine and glutathione levels: Protecting against cerulein- and taurocholate-induced acute pancreatitis in rats. Pancreas 1996;13:173-183.
44. Lüthen R, Grendell JH: Thiol metabolism and acute pancreatitis: Trying to make the pieces fit. Gastroenterology 1994;107:888-892.
45. Wacke R, Kirchner A, Prall F, Nizze H, Schmidt W, Fischer U, Nitsschke FP, Adam U, Fritz P, Belloc C, Drewelow B: Up-regulation of cytochrome P450 1A2, 2C9, and 2E1 in chronic pancreatitis. Pancreas 1998;16:521-528.
46. Baron J, Voight JM, Whitter TB, Kawabata TT, Knapp SA, Guengerich FP, Jakoby WB: Identification of intratissue sites for xenobiotic activation and detoxification. Adv Exp Med Biol 1986;197:119-144.
47. Norton ID, Apte MV, Haber PS, McCaughan GW, Pirola RC, Wilson JS: Cytochrome P4502E1 is present in rat pancreas and is induced by chronic ethanol administration. Gut 1997;42:426-430.
48. Altomare E, Grattagliano I, Vendemiale G, Palmieri V, Palasciano G: Acute ethanol administration induces oxidative changes in rat pancreatic tissue. Gut 1996;38:742-7.
49. Schoenberg MH, Büchler MW, Pietrzyk C, Uhl W, Birt D, Eisele S, Marzinzig M, Beger HG: Lipid peroxidation and glutathione metabolism in chronic pancreatitis. Pancreas 1995;10: 36-43.
50. Basso D, Panozzo MP, Fabris C, del Favero G, Meggiato T, Fogar P, Meani A, Faggian D, Plebani M, Burlina A, Naccarato R: Oxygen derived free radicals in patients with chronic pancreatic and other digestive diseases. J Clin Pathol 1990;43:403-405.
51. Segal I, Gut A, Schofield D, Sheil N, Braganza JM: Micronutrient antioxidant status in black South Africans with chronic pancreatitis: Opportunity for prophylaxis. Clin Chim Acta 1995;239:71-79.
52. Braganza JM, Schofield D, Snehalatha C, Mohan V: Micronutrient antioxidant status in tropical compared to temperate-zone pancreatitis. Scand J Gastroenterol 1993;28:1098-1104.
53. Van Gossum A, Closset P, Noel E, Cremer M, Neve J: Deficiency in antioxidant factors in patients with alcohol-related chronic pancreatitis. Dig Dis Sci 1996;41:1225-1231.
54. Twersky Y, Bank S, Greenberg R: Endogenous antioxidants in chronic pancreatitis. Pancreas 1989;4:646.
55. Dítě P, Prěcechtelová M, Soška V, Lata J: Oxygen radicals and long-term antioxidant therapy in chronic pancreatitis patients (abstract). Digestion 1998;59(suppl 3):504.