Chronic phenobarbital therapy reduces plasma benzodiazepine concentrations after intravenous and rectal administration of diazepam in the dog

Journal of Veterinary Pharmacology and Therapeutics

Volumn 21, Issue 5, 1998, Pages 335-341

  Wagner, S O ^a   Sams, R A ^a   Podell, M ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; NORDAZEPAM; OXAZEPAM; PHENOBARBITAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DOG; DOSE TIME EFFECT RELATION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; EMERGENCY TREATMENT; FLUORESCENCE POLARIZATION IMMUNOASSAY; INTRAVENOUS DRUG ADMINISTRATION; LIVER CLEARANCE; LONG TERM CARE; MEAN RESIDENCE TIME; NEUROLOGIC DISEASE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RECTAL DRUG ADMINISTRATION; SEIZURE;

ADMINISTRATION, ORAL; ADMINISTRATION, RECTAL; ANIMALS; ANTICONVULSANTS; BENZODIAZEPINES; DIAZEPAM; DOGS; EPILEPSY; INJECTIONS, INTRAVENOUS; LIVER; PHENOBARBITAL;

ANIMALIA; CANIS FAMILIARIS;

EID: 0031737095     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2885.1998.00149.x     Document Type: Article

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