Long chain versus medium chain lipids in patients with ARDS: Effects on pulmonary haemodynamics and gas exchange

Intensive Care Medicine

Volumn 24, Issue 10, 1998, Pages 1029-1033

  Smirniotis, V ^a,b   Kostopanagiotou, G ^a   Vassiliou, J ^a   Arkadopoulos, N ^a   Vassiliou, P ^a   Datsis, A ^a   Kourias, E ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b NONE   (Greece)

Author keywords

ARDS; Fat emulsion; Gas exchange; Long chain triglycerides; Medium chain triglycerides; Pulmonary haemodynamics

Indexed keywords

LIPID EMULSION; LONG CHAIN TRIACYLGLYCEROL; MEDIUM CHAIN TRIACYLGLYCEROL;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GAS EXCHANGE; HUMAN; INTENSIVE CARE; INTRAVENOUS DRUG ADMINISTRATION; LUNG ARTERY PRESSURE; LUNG HEMODYNAMICS; MALE; OXYGEN CONSUMPTION; RANDOMIZED CONTROLLED TRIAL; SEPSIS; STATISTICAL ANALYSIS;

ADULT; AGED; BLOOD GAS ANALYSIS; ENERGY INTAKE; FAT EMULSIONS, INTRAVENOUS; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MIDDLE AGED; NUTRITIONAL REQUIREMENTS; OXYGEN CONSUMPTION; PROSPECTIVE STUDIES; PULMONARY CIRCULATION; PULMONARY GAS EXCHANGE; PULMONARY WEDGE PRESSURE; RESPIRATORY DISTRESS SYNDROME, ADULT; SEPSIS; TRIGLYCERIDES;

EID: 0031736706     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340050711     Document Type: Article

References (28)

1. Venus B, Smith AR, Patel CB, Sandoval E (1989) Haemodynamic and gas exchange alterations during Intralipid infusion in patient with adult respiratory distress syndrome. Chest 95: 1278-1281
2. Askanazi J, Carpentier YA, Elwin DH (1980) Influence of total parenteral nutrition on fuel utilisation in injury and sepsis. Ann Surg 191: 40-46
3. Carpentier YA, Richelle M, Haumont D. Deckelbaum RJ (1990) New developments in fat emulsions. Proc Nutr Soc 49: 375-380
4. Crowe PJ, Dennison AR, Royle GT (1985) A new intravenous emulsion containing medium chain triglyceride: Studies of its metabolic effects in the perioperative period compared with a conventional long chain triglyceride emulsion. J Parenter Enter Nutr 9: 720-724
5. Venus B, Prager R, Patel CB, Sandoval E, Sloan P, Smith RA (1988) Cardiopulmonary effects of Intralipid infusion in critically ill patients. Crit Care Med 16: 587-590
6. Chassard D, Guiraud M, Gauthier J, Gelas P, Berrada KR, Bouletreau P (1994) Effects of intravenous medium-chain triglycerides on pulmonary gas exchanges in mechanically ventilated patients. Crit Care Med 22: 248-251
7. Hwang TL, Huang SL, Chen MF (1990) Effects of intravenous fat emulsion on respiratory failure. Chest 97: 934-938
8. Skeie B, Askanazi J, Rothkopf MM, Rosenbaum SH, Kvetan V, Thomashow B (1988) Intravenous fat emulsions and lung function: a review. Crit Care Med 16: 183-194
9. Eckart J, Adolph M, Van der Muhlen U, Naab V (1980) Fat emulsions containing medium chain triglycerides in parenteral nutrition of intensive care patients. J Parenter Enter Nutr 4: 360-366
10. Ball MJ, White K (1989) Comparison of medium and long chain triglyceride metabolism in intensive care patients on parenteral nutrition. Intensive Care Med 15: 250-254
11. Bach AC, Bahayan VK (1982) Medium-chain triglycerides: An update. Am J Clin Nutr 36: 950-962
12. Jiang ZM, Zhang SY, Wang XR, Yang NF, Zhu Y, Wilmore D (1993) A comparison of medium chain and long chain triglycerides in surgical patients. Ann Surg 217: 175-184
13. Dowes RFH, Royle GT, Dennison AR, Crowe PJ, Ball M (1986) Metabolic studies at a lipid emulsion containing medium chain triglyceride in perioperative and total parenteral nutrition infusions. World J Surg 10: 38-46
14. Radermacher P, Santak B, Strobach H, Schror K, Tarnow J (1992) Fat emulsions containing medium chain triglycerides in patients with sepsis syndrome: effects on pulmonary haemodynamics and gas exchange. Intensive Care Med 18: 231-234
15. Bach AC, Cuiraud M, Gibault FP, Schirardin H, Frey A, Bouletreau P (1988) Medium chain triglycerides in septic patients on total parenteral nutrition. Clin Nutr 7: 157-163
16. Talbott GD, Frayser R (1963) Hyperlipidaemia: a cause of decreased oxygen saturation. Nature 200: 684-686
17. Hageman JR, McCulloch K, Gora P, Olsen EK, Pachman L, Hunt CE (1983) Intralipid alterations in pulmonary prostaglandin metabolism and gas exchange. Crit Care Med 11: 794-798
18. Hageman JR, Hunt CE (1986) Fat emulsions and lung function. Clin Chest Med 7: 69-77
19. Hunt CE, Cora P, Inwood RJ (1981) Pulmonary effects of intralipid: the role of intralipid as a prostaglandin precursor. Prog Lipid Res 20: 199-204
20. Radermacher P, Santak B, Wust HJ, Tarnow J, Falke KJ (1990) Prostacyclin for the treatment of pulmonary hypertension in adult respiratory distress syndrome: effect on pulmonary capillary pressure and ventilation-perfusion distributions. Anaesthesiology 72: 238-244
21. Marthru M, Dries DJ, Zecca A, Fareed J, Rooney MW, Rao TLK (1995) Pulmonary haemodynamics and prostaglandin metabolism. Chest 99: 426-429
22. Murray JF, Matthay MA, Luce JM, Flick M (1988) An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 138: 720-723
23. Sirio CA, Knaus WA (1992) Triage and assessment of severity of illness. In: Hall JB, Schmidt GA, Wood LDH (eds) Principles of Critical Care. McGraw-Hill, New York, pp 551-557
24. Long CL (1980) Energy and protein needs in the critically ill patient. Contemp Surg 16: 29-42
25. Sundstrom G, Zauner CW. Arborelius M (1973) Decrease in pulmonary diffusing capacity during lipid infusion in healthy men. J Appl Physiol 34: 816-820
26. Greene HL, Hazlett D, Demaree R (1976) Relationship between Intralipid-induced hyperlipemia and pulmonary function. Am J Clin Nutr 29: 127-135
27. McKeen CR, Brigham KL, Bowers RE, Harris TR (1978) Pulmonary vascular effects of fat emulsion in unanesthetised sheep. Am Soc Clin Invest 57: 1291-1297
28. Inwood RJ, Gora P, Hunt CE (1981) Indomethacin inhibition of Intralipid-induced lung dysfunction. Prostaglandins Med 6: 503-514