Analysis of antibody response to the outer surface protein family in lyme borreliosis patients

Journal of Infectious Diseases

Volumn 178, Issue 6, 1998, Pages 1676-1683

  Batsford, Stephen ^b   Rust, Christian ^a   Neubert, Uwe ^c  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; IMMUNOGLOBULIN G ANTIBODY; OUTER MEMBRANE PROTEIN;

ACTIVE IMMUNIZATION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; BACTERIUM ISOLATION; BORRELIA BURGDORFERI; BORRELIA INFECTION; CLINICAL ARTICLE; HUMAN; IMMUNOGENICITY; PRIORITY JOURNAL;

ACRODERMATITIS; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; ARTHRITIS; BACTERIAL OUTER MEMBRANE PROTEINS; BORRELIA BURGDORFERI GROUP; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERYTHEMA; FRANCE; GENOTYPE; GERMANY; HUMANS; LYME DISEASE; SKIN; TICKS; UNITED STATES;

EID: 0031736511     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314477     Document Type: Article

References (25)

1. Barbour AG, Garon CF. The genes encoding major surface proteins of Borrelia burgdorferi are located on a plasmid. Ann NY Acad Sci 1988;539:144-53.
2. Wallich R, Helmes C, Schaible UE, et al. Evaluation of genetic divergence among Borrelia burgdorferi isolates by use of OspA, fla, HSP60, and HSP70 gene probes. Infect Immun 1992;60:4856-66.
3. Fikrig E, Huguenel ED, Berland R, Rahn DW, Hardin JA, Flavell RA. Serologic diagnosis of Lyme disease using recombinant outer surface proteins A and B and flagellin. J Infect Dis 1992;165:1127-32.
4. Assous MV, Postic D, Paul G, Nevot P, Baranton G. Western blot analysis of sera from Lyme borreliosis patients according to the genomic species of the Borrelia isolates used as antigens. Eur J Clin Microbiol Infect Dis 1993;12:261-8.
5. Shanafelt MC, Anzola J, Soderberg C, Yssel H, Turck CW, Peltz G. Epitopes on the outer surface protein A of Borrelia burgdorferi recognized by antibodies and T cells of patients with Lyme disease. J Immunol 1992;148:218-24.
6. Wilske B, Fingerle V, Herzer P, et al. Recombinant immunoblot in the serodiagnosis of Lyme borreliosis. Comparison with indirect immunofluoreseence and enzyme-linked immunosorbent assay. Med Microbiol Immunol (Berl) 1993;182:255-70.
7. Dressler F, Whalen JA, Reinhardt BN, Steere AC. Western blotting in the serodiagnosis of Lyme disease. J Infect Dis 1993;167:392-400.
8. Kowal K, Weinstein A. Western blot band intensity analysis. Application to the diagnosis of Lyme arthritis. Arthritis Rheum 1994;37:1206-11.
9. Dressler F, Ackermann R, Steere AC. Antibody responses to the three ge-nomic groups of Borrelia burgdorferi in European Lyme borreliosis. J Infect Dis 1994;169:313-8.
10. Kalish RA, Leong JM, Steere AC. Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi. Infect Immun 1993;61:2774-9.
11. Yoshinari Nil, Reinhardt BN, Steere AC. T cell responses to polypeptide fractions of Borrelia burgdorferi in patients with Lyme arthritis. Arthritis Rheum 1991;34:707-13.
12. Lengl Janssen B, Strauss AF, Steere AC, Kamradt T. The T helper cell response in Lyme arthritis: differential recognition of Borrelia burgdorferi outer surface protein A in patients with treatment-resistant or treatment-responsive Lyme arthritis. J Exp Med 1994;180:2069-78.
13. Kalish RA, Leong JM, Steere AC. Early and late antibody responses to full-length and truncated constructs of outer surface protein A of Borrelia burgdorferi in Lyme disease. Infect Immun 1995;63:2228-35.
14. Gondolf KB, Mihatsch M, Curschellas E, Dunn JJ, Batsford SR. Induction of experimental allergic arthritis with outer surface proteins of Borrelia burgdorferi. Arthritis Rheum 1994;37:1070-7.
15. Baranton G, Postic D, Saint Girons I, et al. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int J Syst Bacteriol 1992;42:378-83.
16. Adam T, Gassmann GS, Rasiah C, Göbel UB. Phenotypic and genotypic analysis of Borrelia burgdorferi isolates from various sources. Infect Immun 1991;59:2579-85.
17. Wilske B, Praec-Mursic V, Göbel UB, et al. An OspA serotyping system for Borrelia burgdorferi based on reactivity with monoclonal antibodies and OspA sequence analysis. J Clin Microbiol 1993;31:340-50.
18. Barbour AG. Isolation and cultivation of Lyme disease spirochetes. Yale J Biol Med 1984;57:521-5.
19. Gondolf KB, Batsford SR, Vogt A. Isolation of an outer membrane protein complex from Borrelia burgdorferi by n-butanol extraction and high-performance ion-exchange chromatography. J Chromatogr 1990;521:325-34.
20. Dunn JJ, Lade BN, Barbour AG. Outer surface protein A (OspA) from the Lyme disease spirochete, Borrelia burgdorferi: high level expression and purification of a soluble recombinant form of OspA. Protein Expression Purification 1990;1:159-68.
21. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
22. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
23. Schutzer SE, Coyle PK, Dunn JJ, Luft BJ, Brunner M. Early and specific antibody response to OspA in Lyme disease. J Clin Invest 1994;94:454-7.
24. Karlsson M. Antibody response against autologous and heterologous isolates of Borrelia burgdorferi in four patients with Lyme neuroborreliosis. Eur J Clin Microbiol Infect Dis 1991;10:742-5.
25. Ohlenbusch A, Matuschka FR, Richter D, et al. Etiology of the acrodermatitis chronica atrophicans lesion in Lyme disease. J Infect Dis 1996;174:421-3.