Effects of gabapentin on cognition and quality of life in patients with epilepsy

Seizure

Volumn 7, Issue 5, 1998, Pages 359-364

  Mortimore, Catherine ^a   Trimble, Michael ^a   Emmers, Elke ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Antiepileptic drugs; Cognitive function; Epilepsy; Gabapentin; Quality of life

Indexed keywords

ANTICONVULSIVE AGENT; GABAPENTIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRITICAL FLICKER FUSION; DRUG EFFECT; EPILEPSY; FEMALE; HUMAN; MALE; MOOD; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; QUALITY OF LIFE; RECALL; RECOGNITION; VERBAL MEMORY;

EID: 0031736342     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1059-1311(05)80003-2     Document Type: Article

References (16)

1. Thompson, P.J. and Trimble, M.R. Neuropsychological aspects of epilepsy. In: Neuropsychological Assessment of Neuropsychiatric Disorders. 2nd Edition (Eds I. Grant and K.M. Adams). New York, Oxford University Press, 1996: pp. 263-287.
2. Trimble, M.R. Anticonvulsant drugs and cognitive function: a review of the literature. Epilepsia 1987; 28 (Suppl. 3): 37-45.
3. Trimble, M.R. Quality of life and cognitive function. In: Epilepsy and Quality of Life. (Eds M.R. Trimble and W.E. Dodson). New York, Raven Press, 1994: pp. 183-198.
4. Dijkstra, J.B., McGuire, A.M. and Trimble, M.R. The effect of vigabatrin on cognitive function and mood. Human Psychopharmacology 1992; 7: 319-323.
5. Thomas, L. and Trimble, M.R. The effects of vigabatrin on attention, concentration and mood: an investigation in healthy volunteers. Seizure 1996; 5: 205-208.
6. Hindmarch, I. Critical Flicker Fusion frequency (CFF): the effects of psychotropic compounds. Pharmacopsychiatry 1982; 15 (Suppl. 1): 44-48.
7. Rey, A. In: Neuropsychological Assessment. 3rd Edition (Ed. M. Lezak). Oxford University Press, 1995.
8. Gronwall, D.M.A. Paced serial-addition task: a measure of recovery from concussion. Perceptual & Motor Skills 1977; 44: 365-373.
9. Trenerry, M.R., Crosson, B., DeBoe, J. and Leber, W.R. Stroop Neuropsychological Screening Test Manual, Psychological Assessment Resources, 1989.
10. Goldberg, D. and Williams, P. A User's Guide to the General Health Questionnaire. NFER-Nelson, 1988.
11. Vickrey, B.G., Hays, R.D., Graber, J., Rausch, R., Engle, J. and Brook, R.H. A health-related quality of life instrument for patients evaluated for epilepsy surgery. Medical Care 1992; 30: 299-319.
12. Leach, J.P., Girvan, J., Paul, A. and Brodie, M.J. Gabapentin and cognition: a double blind, dose ranging, placebo controlled study in refractory epilepsy. Journal of Neurology, Neurosurgery, Neuropsychiatry 1997; 62: 372-376.
13. Arnett, J.L., Dodrill, C.B., Garofalo, E.A., Hayes, A.G., Pierce, M.W. and Arbor, A. Neuropsychological, mood and psychosocial effects of gabapentin (in press).
14. Dimond, K.R., Pande, A.C., LaMoreaux, L. and Pierce, M.W. Effect of gabapentin on mood and well being in patients with epilepsy. Progress in Neuro-psychopharmacology and Biological Psychiatry 1996; 20: 407-417.
15. Trimble, M.R. Anticonvulsant drugs: mood and cognitive function. In: Epilepsy, Behaviour and Cognitive Function. (Eds M.R. Trimble and E.H. Reynolds). Chichester, Wiley, 1988: pp. 135-144.
16. Ryback, R.S., Brodsky, L. and Munasifi, F. Gabapentin in bipolar disorder. Journal of Neuropsychiatry 1997; 9: 301.