Total synthesis and DNA-cleaving properties of thiarubrine C

Journal of Organic Chemistry

Volumn 63, Issue 24, 1998, Pages 8644-8645

  Wang, Yamin ^a   Koreeda, Masato ^a   Chatterji, Tonika ^b   Gates, Kent S ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; REACTIVE OXYGEN METABOLITE; THIARUBRINE C; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DNA DAMAGE; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 0031735791     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo981849p     Document Type: Article

References (27)

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10. All of our assays were prepared under red light (darkroom) and were incubated in the dark, as it is known that the thiarubrines are photoreactive: Block, E.; Page, J.; Toscano, J. P.; Wang, C.-X.; Zhang, X.; DeOrazio, R.; Guo, C.; Sheridan, R. S.; Towers, C. H. N. J. Am. Chem. Soc. 1996, 118, 4719-4720. See also ref 1.
11. 4 (5 mol %)/benzene, rt, 12 h] in 85% overall yield.
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