Effects of aldose reductase inhibitors, AL-4114 and AL-1576, on hepatic biotransformation in rabbit and rat

International Journal of Toxicology

Volumn 17, Issue 6, 1998, Pages 603-617

  Veltman, J C ^a   Kumar, A ^b   Sanders, R A ^b   Watkins III, J B ^b  

^a ALCON RESEARCH LTD   (United States)

^b Indiana University School of Medicine   (United States)

Author keywords

Aldose reductase inhibitors; Biotransformation; Cytochrome P450 monooxygenase; Glucuronosyltransferase; Liver; Rabbit; Rat

Indexed keywords

AL 4114; ALDOSE REDUCTASE INHIBITOR; CYTOCHROME P450; DEXAMETHASONE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; IMIRESTAT; LIVER ENZYME; UNCLASSIFIED DRUG;

BIOTRANSFORMATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; EYE; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER METABOLISM; NONHUMAN; PROTEIN DETERMINATION; RABBIT; REVIEW; TOPICAL DRUG ADMINISTRATION;

ORYCTOLAGUS CUNICULUS;

EID: 0031735676     PISSN: 10915818     EISSN: None     Source Type: Journal    
DOI: 10.1080/109158198225874     Document Type: Review

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