A case study of employing spectroscopic tools for monitoring reactions in the developmental stage of a combinatorial chemistry library

Journal of Organic Chemistry

Volumn 63, Issue 24, 1998, Pages 8719-8722

  Luo, Ying ^a   Ouyang, Xiaohu ^a   Armstrong, Robert W ^a   Murphy, Martin M ^a,b  

^a AMGEN INC   (United States)

^b PROTEIN DESIGN LABS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYSTYRENE DERIVATIVE; RESIN;

ARTICLE; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; SYNTHESIS;

EID: 0031735412     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo980322+     Document Type: Article

References (25)

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2. For recent reviews on solid-phase organic synthesis, see: (a) Thompson, M. A.; Ellman, J. A. Chem. Rev. 1996, 96, 555-600. (b) Terrett, N. K.; Gardner, M.; Gordon, D. W.; Kobylecki, R. J.; Steele, J. Tetrahedron 1995, 51, 8135-8173. Fruchtel, J. S.; Jung, G. Angew. Chem., Int. Ed. Engl. 1996, 35, 17-42. Balkenhohl, F.; von dem Bussche-Hunnefeld, C.; Lansky, A.; Zechel, C. Angew. Chem., Int. Ed. Engl. 1996, 35, 2288-2337.
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20. Resin purchased and used as is from Novabiochem.
21. -1 band is from the tertiary amine salt 4.
22. -1 band is from the tertiary amine salt 4.
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24. Supporting data found in Supporting Information.
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