The effects of mifepristone on cervical ripening and labor induction in primigravidae

Obstetrics and Gynecology

Volumn 92, Issue 5, 1998, Pages 804-809

  Elliott, Catherine L ^a   Brennand, Janet E ^a   Calder, Andrew A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MIFEPRISTONE; OXYTOCIN; PROSTAGLANDIN E2;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG DISTRIBUTION; DRUG EFFICACY; FEMALE; HUMAN; LABOR INDUCTION; MAJOR CLINICAL STUDY; ORAL DRUG ADMINISTRATION; PRIMIGRAVIDA; PRIORITY JOURNAL; UMBILICAL CORD BLOOD; UTERINE CERVIX DILATATION;

ADOLESCENT; ADULT; CERVICAL RIPENING; DOUBLE-BLIND METHOD; FEMALE; GRAVIDITY; HUMANS; HYPOGLYCEMIA; INFANT, NEWBORN; LABOR, INDUCED; MATERNAL-FETAL EXCHANGE; MIFEPRISTONE; PREGNANCY; RISK FACTORS;

EID: 0031735215     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0029-7844(98)00284-1     Document Type: Article

References (14)

1. Calder A.A., Greer I.A. Prostaglandins and the cervix. Clin Obstet Gynecol. 6:1992;771-786.
2. Keirse M.J.N.C. Therapeutic uses of prostaglandins. Clin Obstet Gynecol. 6:1992;787-808.
3. Greer I.A. Cervical ripening. Drife J.O., Calder A.A. Prostaglandins and the uterus. 1992;191-209 Springer Verlag, London.
4. Spitz I.M., Bardin C.W. Clinical pharmacology of RU486 - an antiprogestin and antiglucocorticoid. Contraception. 48:1993;403-444.
5. 1 analogue) alone and mifepristone and gemeprost . Br J Obstet Gynaecol. 99:1992;601-606.
6. Henshaw R.C., Templeton A.A. Pre-operative cervical preparation before first trimester vacuum aspiration A randomized controlled comparison between gemeprost and mifepristone . Br J Obstet Gynaecol. 98:1991;1025-1030.
7. The use of mifepristone (RU486) for cervical preparation in first trimester pregnancy termination by vacuum aspiration. Br J Obstet Gynaecol. 97:1990;260-266.
8. Rodger M.W., Baird D.T. Pretreatment with mifepristone (RU486) reduces the interval between prostaglandin administration and expulsion in second trimester abortion. Br J Obstet Gynaecol. 97:1990;41-45.
9. Wolf J.P., Sinosich M., Anderson T.L., Ulmann A., Baulieu E.E., Hodgen G.D. Progesterone antagonist (RU486) for cervical dilatation, labour induction and delivery in monkeys Effectiveness in combination with oxytocin . Am J Obstet Gynecol. 160:1989;45-47.
10. Frydman R., Lelaidier C., Baton-Saint-Mleux C., Fernandez H., Vial M., Bourget P. Labour induction in women at term with mifepristone (RU486) A double-blind, randomized, placebo-controlled study . Obstet Gynecol. 80:1992;972-975.
11. Wolf J.P., Chillik C.F., Itskovitz J., Weyman D., Anderson T.L., Ulmann A., et al. Transplacental passage of a progesterone antagonist in monkeys. Am J Obstet Gynecol. 159:1988;238-242.
12. Hill N.C.W., Selinger M., Ferguson J., MacKenzie I.Z. The placental transfer of mifepristone (RU486) during the second trimester and its influence upon maternal and fetal steroid concentrations. Br J Obstet Gynaecol. 97:1990;406-411.
13. 2 in viscous gel before induction of labour. Br J Obstet Gynaecol. 84:1977;264-268.
14. Wolf J.P., Simon J., Itskovitz J., Sinosich M.J., Ulmann A., Baulieu E.E., et al. Progesterone antagonist RU486 accommodates but does not induce labour and delivery in primates. Hum Reprod. 8:1993;759-763.