Tumor-specific activation of mitogen-activated protein kinase in human colorectal and gastric carcinoma tissues

Japanese Journal of Cancer Research

Volumn 89, Issue 9, 1998, Pages 903-909

  Kuno, Yasushi ^a   Kondo, Ken ^a   Iwata, Hiroyuki ^a   Senga, Takeshi ^a   Akiyama, Seiji ^a   Ito, Katsuki ^a   Takagi, Hiroshi ^a   Hamaguchi, Michinari ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Gastric carcinoma; Human colorectal carcinoma; MAP kinase; Signal transduction

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; STOMACH CARCINOMA;

EID: 0031735019     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1998.tb00647.x     Document Type: Article

References (28)

1. Nishida, E. and Gotoh, Y. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends. Biochem. Sci., 18, 128-131 (1993).
2. Blenis, J. Signal transduction via the MAP kinases: proceed at your own RSK. Proc. Natl. Acad. Sci. USA, 90, 5889-5892 (1993).
3. Marshall, C. J. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr. Opin. Genet. Dev., 4, 82-89 (1994).
4. Dent, P., Haser, W., Haystead, T. A. J., Vincent, L. A., Roberts, T. M. and Sturgill, T. W. Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro. Science, 257, 1404-1407 (1992).
5. Howe, L. R., Leevers, S. J., Gomez, N., Nakielny, S., Cohen, P. and Marshall, C. J. Activation of the MAP kinase pathway by the protein kinase Raf. Cell, 71, 335-342 (1992).
6. Hughes, D. A., Ashworth, A. and Marshall, C. J. Complementation of byr1 in fission yeast by mammalian MAP kinase kinase requires coexpression of Raf kinase. Nature, 364, 349-352 (1993).
7. Macdonald, S. G., Crews, C. M., Wu, L., Driller, J., Clark, R., Erikson, R. L. and Mccormick, F. Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro. Mol. Cell. Biol., 13, 6615-6620 (1993).
8. Cowley, S., Paterson, H., Kemp, P. and Marshall, C. J. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell, 77, 841-852 (1994).
9. Mansour, S. J., Matten, W. T., Hermann, A. S., Candia, J. M., Rong, S., Fukasawa, K., Vande Woude, G. F. and Ahn, N. G. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science, 265, 966-970 (1994).
10. Foulds, L. The natural history of cancer. J. Chronic Dis., 8, 2-37 (1958).
11. Fearon, E. R. and Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61, 759-767 (1990).
12. c-src protein kinase activity in human colon carcinoma. Proc. Natl. Acad. Sci. USA, 84, 2251-2255 (1987).
13. Slamon, D. J., Godolphin, W., Jones, L. A., Holt, J. A., Wong, S. G., Keith, D. E., Levin, W. J., Stuart, S. G., Udove, J., Ullrich, A. and Press, M. F. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science, 244, 707-712 (1989).
14. Berchuck, A., Kamel, A., Whitaker, R., Kerns, B., Olt, G., Kinney, R., Soper, J. T., Dodge, R., Clarke-Pearson, D. L., Marks, P., Mckenzie, S., Yin, S. and Bast, R. C. J. Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer. Cancer Res., 50, 4087-4091 (1990).
15. Kameda, T., Yasui, W., Yoshida, K., Tsujino, T., Nakayama, H., Ito, M., Ito, H. and Tahara, E. Expression of ERBB2 in human gastric carcinomas: relationship between p185ERBB2 expression and the gene amplification. Cancer Res., 50, 8002-8009 (1990).
16. Kern, J. A., Schwartz, D. A., Nordberg, J. E., Weiner, D. B., Greene, M. I., Torney, L. and Robinson, R. A. p185neu expression in human lung adenocarcinomas predicts shortened survival. Cancer Res., 50, 5184-5187 (1990).
17. Ware, J. L., Maygarden, S. J., Koontz, W. W., Jr. and Strom, S. C. Immunohistochemical detection of c-erbB-2 protein in human benign and neoplastic prostate. Hum. Pathol., 22, 254-258 (1991).
18. Seshadri, R., Firgaira, F. A., Horsfall, D. J., Mccaul, K., Setlur, V. and Kitchen, P. Clinical significance of HER-2/neu oncogene amplification in primary breast cancer. J. Clin. Oncol., 11, 1936-1942 (1993).
19. Nishimura, M., Machida, K., Imaizumi, M., Abe, T., Umeda, T., Takeshima, E., Watanabe, T., Ohnishi, Y., Takagi, K. and Hamaguchi, M. Tyrosine phosphorylation of 100-130 kDa proteins in lung cancer correlates with poor prognosis. Br. J. Cancer, 74, 780-787 (1996).
20. Shibata, K., Kikkawa, F., Nawa, A., Suganuma, N. and Hamaguchi, M. Fibronectin secretion from human peritoneal tissue induces Mr 92,000 type IV collagenase expression and invasion in ovarian cancer cell lines. Cancer Res., 57, 5416-5420 (1997).
21. Shibata, K., Kikkawa, F., Nawa, A., Thant, A. A., Naruse, K., Mizutani, S. and Hamaguchi, M. Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase-9 (MMP-9) secretion by fibronectin in the ovarian cancer cells. Cancer Res., 58, 900-903 (1998).
22. Atten, M. J., Attar, B. M. and Holian, O. Decreased MAP kinase activity in human gastric adenocarcinoma. Biochem. Biophys. Res. Commun., 212, 1001-1006 (1995).
23. Oka, H., Chatani, Y., Hoshino, R., Ogawa, O., Kakehi, Y., Terachi, T., Okada, Y., Kawaichi, M., Kohno, M. and Yoshida, O. Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma. Cancer Res., 55, 4182-4187 (1995).
24. Hamaguchi, M., Grandori, C. and Hanafusa, H. Phosphorylation of cellular proteins in Rous sarcoma virus-infected cells: analysis by use of anti-phosphotyrosine antibodies. Mol. Cell. Biol., 8, 3035-3042 (1988).
25. v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J., 12, 559-564 (1993).
26. Hattori, S., Fukuda, M., Yamashita, T., Nakamura, S., Gotoh, Y. and Nishida, E. Activation of mitogen-activated protein kinase and its activator by ras in intact cells and in a cell-free system. J. Biol. Chem., 267, 20346-20351 (1992).
27. Grinstein, S., Butler, J. R., Furuya, W., Lallemain, G. and Downey, G. P. Chemotactic peptides induce phosphorylation and activation of MEK-1 in human neutrophils. J. Biol. Chem., 269, 19313-19320 (1994).
28. Itoh, T., Kaibuchi, K., Masuda, T., Yamamoto, T., Matsuura, Y., Maeda, A., Shimizu, K. and Takai, Y. A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase. Proc. Natl. Acad. Sci. USA, 90, 975-979 (1993).