Stereoisomers of 3-(2,3-dihydrobenzofuran-2-yl)quinuclidine: Preparation and muscarinic receptor affinities

Chirality

Volumn 10, Issue 9, 1998, Pages 813-820

  Johansson, Gary ^a   Brisander, Magnus ^b   Sundquist, Staffan ^c   Hacksell, Uli ^a,d  

^a UPPSALA UNIVERSITY   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c PFIZER INC   (United States)

^d ASTRAZENECA R AND D   (Sweden)

Author keywords

Borane complexes; Chromatographic separation; Fractional crystallization; Quinuclidine derivatives; Resolution; X ray crystallography

Indexed keywords

3 (2,3 DIHYDROBENZOFURAN 2 YL)QUINUCLIDINE DERIVATIVE; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; QUINUCLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIASTEREOISOMER; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; RACEMIC MIXTURE; RECEPTOR AFFINITY; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; GUINEA PIGS; MUSCARINIC ANTAGONISTS; QUINUCLIDINES; RECEPTORS, MUSCARINIC; STEREOISOMERISM;

EID: 0031734747     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1998)10:9<813::AID-CHIR7>3.0.CO;2-G     Document Type: Article

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