Distribution and excretion of boron after intravenous administration of disodium mercaptoundecahydro-closo-dodecaborate to rats

Journal of Toxicological Sciences

Volumn 23, Issue SUPPL. 4, 1998, Pages 577-585

  Yamaguchi, Toshiro ^a   Nakajima, Yoshitsugu ^a   Miyamoto, Hiroyuki ^b   Mizobuchi, Minoru ^a   Kanazu, Takushi ^a   Kadono, Kyoko ^a   Nakamoto, Kayo ^a   Ikeuchi, Isao ^b  

^a SHIONOGI AND CO LTD   (Japan)

^b Chemical Analysis Laboratories   (Japan)

Author keywords

Boron compound; Distribution; Excretion; Rats

Indexed keywords

BOROCAPTATE; BORON;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; ATOMIC EMISSION SPECTROMETRY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY FUNCTION; MALE; NEUTRON CAPTURE THERAPY; NONHUMAN; RAT;

ANIMALIA;

EID: 0031734503     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.23.supplementiv_577     Document Type: Article

References (24)

1. Abe M., Amano K., Kitamura K., Tateishi J. and Hatanaka H. (1986) : Boron distribution analysis by alpha-autoradiography. J. Nucl. Med., 27, 677-684.
2. Barth R. F., Soloway A. H. and Fairchild R. G. (1990) : Boron neutron capture therapy for cancer. Cancer. Res., 50, 1061-1070.
3. Buchar E., Bednarova S., Gruner B., Walder P., Strouf O. and Janku I. (1992) : Dose-dependent disposition kinetics and tissue accumulation of boron after intravenous injections of sodium mercaptoundecahydrododecaborate in rabbits. Cancer Chemother. Pharmacol., 29, 450-454.
4. Carlsson J., Sjoberg S. and Larsson B.(1992).: Present status of boron neutron capture therapy. Acta Oncol., 31, 803-813.
5. Clandenon N. R., Barth R. F., Gordon W. A., Goodman J. H., Alam F., Staubus A. E., Boesel C. P., Yates A. J., Moeshberger M. L., Fairchild R. G. and Kalef-Ezra J. A. (1990) : Boron neutron capture therapy of a rat glioma. Neurosurgery, 26, 47-55.
6. Gabel D., Holstein H., Larsson B., Gille L., Ericson G., Sacker D., Som P. and Fairchild R. (1987) : Quantitative neutron capture radiography for studying the biodistribution of tumor-seeking boron containing compounds. Cancer Res., 47, 5451-5454.
7. Hatanaka H., Sano K. and Yasukochi K. (1992) : Clinical results of boron capture therapy. In Progress in Neutron Capture Therapy for Cancer (B. Allen, D. Moore and B. Harrington eds.), pp. 561-568, Plenum, New York.
8. Hatanaka H. and Nakagawa Y. (1994) : Clinical results of long-surviving brain tumor patients who under-went boron neutron capture therapy. Int. J. Radiat. Oncol. Biol. Phys., 28, 1061-1066
9. Ito F., Yabuuchi K., Ohno K., Muraoka Y. and Ikeuchi I.(1998): Single and 2-week repeated intravenous dose toxicity studies of BSH, a boron compound, in rats. J. Toxicol. Sci., 23, Suppl. IV, 587-611.
10. Joel D., Slatkin D., Fairchild R., Micca P. and Nawrocky M. (1989) : Pharmacokinetics and tissue distribution of the sulfhydryl borons (monomers and dimer) in glioma-bearing rats. Strahlenther. Oncol., 165, 167-170.
11. Kraft S. L., Gavin P. R., DeHann C. E., Leathers C. W., Bauer W. F., Dorn III R. V. (1992) : The biodistribution of boron in canine spontaneous intracranial tumors following borocaptate sodium infusion. Progress in Neuron Capture Therapy for Cancer (B. J. Allen, D. E. Moore and B. V. Harrington, eds.), pp. 537-540, Plenum Press, New York.
12. Kraft S. L., Gavin P. R., Leathers C. W., DeHann C. E., Bauer W. F., Miller D. L., Dorn III R. V. and Griebenow M. L. (1994) : Biodistribution boron in dogs with spontaneous intracranial tumors following borocaptate sodium administration. Cancer Res., 54, 1259-1263 .
13. LaHamn T. R., Lu D. R., Daniel G., Sills C., Kraft S. L., Gavin P. R. and Bauer W. F. (1993) : Bioavailability of intravenous formulations of p-Boronophenylalanine in dog and rat. In Advances in Neutron Capture Therapy (R. F. Barth and A. H. Soloway eds.), pp. 585-589, Plenum, New York.
14. Robert Lu D. and Corey Munro (1992) : Quantitative analysis of mercaptoundecahydrododecaborate by Fourier transform infrared spectroscopy. Pharmaceutical Research, 9, 1199-1202.
15. Mehta S. C., Boudinot F. D. and Lu D. R.(1995) : Pharmacokinetics of sodium mercaptoundecahydrododecaborate after intravenous injection in rats. Drug Metab. Dispos., 23, 1368-1371.
16. Morris G. M., Constantine G., Ross G., Yeung T. K. and Hopewell J. W. (1993) : Boron neutron capture therapy: Long-term effect on the skin and spinal cord of the rat. Radiat. Res., 135, 380-386.
17. Nakagawa Y., Kageji T, Hatanaka H., Moritani M., Kitamura K., Matsumoto K. and Kobayashi M. (1993) : Blood-brain barrier permeability in partially deutrated rat brain. Advances in Neutron Capture Therapy (A. H. Soloway, R. F. Barth and D. E. Carpenter eds.), pp. 509-512, Plenum Press, New York.
18. Nakagawa Y.and Hatanaka H.(1996a) : Recent study of boron neutron capture therapy for malignant brain tumor in Japan. In Proceedings of the 6th international symposium on neutron capture therapy for cancer (Mishima Y., ed.), pp 717-724, Plenum Press, New York.
19. Nakagawa Y., Pooh K., Kageji T., Kitamura K., Komatsu H., Tsuji F., Hatanaka H.and Minobe T.(1996b) : Boron neutron capture therapy for malignant brain tumor in children. In Proceedings of the 6th international symposium on neutron capture therapy for cancer (Mishima Y., ed.), pp 725-731, Plenum Press, New York.
20. Nakagawa Y.and Hatanaka H.(1997) : Boron neutron capture therapy; Clinical brain tumor studies. J. Neuro-Oncology, 33, 105-115.
21. 2 administered to mice. Biochem. Pharmacol., 35, 1771-1776.
22. Soloway A. H., Hatanaka H. and Davis M. A. (1967) : Penetration of brain and brain tumor. VII. Tumorbinding sulfhydral boron compounds. J. Med. Chem., 10, 714-717.
23. Tamat S. R., Moore D. E. and Allen B. J. (1987) : Determination of boron in biological tissues by inductively coupled plasma atomic emission spectrometry. Anal. Chem., 59, 2161-2164.
24. Yamaoka K., Tanigawa Y. and Nakagawa T. (1981) : A pharmacokinetic analysis program (MULTI) for microcomputer. J. Pharm. Dyn., 4, 879-885.