Subacute and chronic toxicity studies of triethylenetetramine dihydrochloride (TJA-250) by oral administration to F-344 rats

Journal of Toxicological Sciences

Volumn 23, Issue SUPPL. 4, 1998, Pages 619-642

  Yanagisawa, Toshihiko ^a   Maemura, Shunichi ^a   Sasaki, Hiromi ^a   Endo, Toru ^a   Okada, Minoru ^a   East, Philip W ^b   Virgo, David M ^b   Creasy, Dianne M ^b  

^a TSUMURA AND CO   (Japan)

^b HUNTINGDON LIFE SCIENCES   (United Kingdom)

Author keywords

Copper chelating agent; Interstitial pneumonitis; Rat; Repeated dose toxicity; Triethylenetetramine dihydrochloride; Wilson's disease

Indexed keywords

ALKALINE PHOSPHATASE; CHELATING AGENT; COPPER; ELECTROLYTE; TJA 250; TRIENTINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD CHEMISTRY; CHRONIC TOXICITY; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; INTERSTITIAL PNEUMONIA; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; TOXICITY; URINALYSIS; WILSON DISEASE;

ANIMALIA;

EID: 0031733858     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.23.supplementiv_619     Document Type: Article

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