Cholera toxin stimulates type II pneumocyte proliferation by a cyclic AMP-independent mechanism

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1405, Issue 1-3, 1998, Pages 99-109

  Uhal, Bruce D ^a   Papp, Michael ^a   Flynn, Kevin ^a   Steck, Mary E ^b  

^a Cardiovascular Associates   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

ADP ribosylation; Alveolar epithelium; Signal transduction

Indexed keywords

8 BROMO CYCLIC AMP; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; LUNG ALVEOLUS CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE DIPHOSPHATE RIBOSE; ADENYLATE CYCLASE; ANIMALS; CELL COUNT; CELL CYCLE; CELL DIVISION; CELLS, CULTURED; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA; EPITHELIAL CELLS; LUNG; PULMONARY ALVEOLI; RATS; SIGNAL TRANSDUCTION;

EID: 0031732398     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(98)00110-4     Document Type: Article

References (40)

1. R.J. Mason, M.C. Williams, Type II alveolar epithelial cells, in: R.G. Crystal, J.B. West (Eds.), The Lung: Scientific Foundations, Raven Press, New York, 1991.
2. 2. Exp. Mol. Pathol. 22:1975;142-150.
3. Adamson I., Bowden D. The type II cell as progenitor of alveolar epithelial regeneration. Lab. Invest. 30:1974;35-42.
4. Witschi H. Responses of the lung to toxic injury. Environ. Health Perspect. 85:1990;5-13.
5. Thaete L.G., Malkinson A.M. Cells of origin of primary pulmonary neoplasms in mice: morphologic and histochemical studies. Exp. Lung Res. 17:1991;219-228.
6. Rehm S., Devor D.E., Henneman J.R., Ward J.M. Origin of spontaneous and transplacentally induced mouse lung tumors from alveolar type II cells. Exp. Lung Res. 17:1991;181-195.
7. Droms K.A., Malkinson A.M. Mechanisms of glucocorticoid involvement in mouse lung tumorigenesis. Exp. Lung Res. 17:1991;359-370.
8. Lange-Carter C.A., Malkinson A.M. Alterations in the cAMP signal transduction pathway in mouse lung tumorigenesis. Exp. Lung Res. 17:1991;341-357.
9. Malkinson A.M., Butley M.S. Alterations in cyclic adenosine 3′:5′-monophosphate-dependent protein kinases during normal and neoplastic lung development. Cancer Res. 41:1981;1334-1341.
10. Rannels S.R., Fisher C.S., Heuser L.J., Rannels D.E. Culture of type II pneumocytes on a type II cell-derived fibronectin-rich matrix. Am. J. Physiol. 253:1987;C759-C765.
11. Rannels S.R., Yarnell J.A., Fisher C.S., Fabisiak J.P., Rannels D.E. Role of laminin in maintenance of type II pneumocyte morphology and function. Am. J. Physiol. 253:1987;C835-C845.
12. Leslie C.C., McCormick-Shannon K., Mason R.J. Heparin-binding growth factors stimulate DNA synthesis in rat alveolar type II cells. Am. J. Respir. Cell. Mol. Biol. 2:1990;99-106.
13. Leslie C.C., McCormick-Shannon K., Robinson P.C., Mason R.J. Stimulation of DNA synthesis in cultured rat alveolar type II cells. Exp. Lung Res. 8:1985;53-66.
14. Messmer T.O., Armour R., Holley R.W. Factors influencing the growth of alveolar type II cells isolated from rat lungs. Exp. Cell Res. 142:1982;417-426.
15. Tanswell A.K., Byrne P.J., Han R.N., Edelson J.D., Han V.K.M. Limited division of low-density adult rat type II pneumocytes in serum-free culture. Am. J. Physiol. Lung Cell. Mol. Physiol. 4:1991;L395-L402.
16. Rybin V.O., Uhal B.D., Russo L.A., Rannels D.E. ADP-ribosylation of type II pulmonary epithelial cell G-proteins. Am. J. Physiol. 260:1991;L539-L547.
17. B.D. Uhal, G.D. Hess, D.E. Rannels, Density-independent isolation of type II pneumocytes after partial pneumonectomy, Am J. Physiol. (1989) C515-C521.
18. B.D. Uhal, S.R. Rannels, D.E. Rannels, Flow cytometric identification and isolation of hypertrophic type II pneumocytes after partial pneumonectomy, Am. J. Physiol. (1989) C528-C536.
19. B.D. Uhal, D.E. Rannels, DNA distribution analysis of type II pneumocytes by laser flow cytometry: technical considerations, Am. J. Physiol. (1991) L296-L306.
20. Uhal B.D., Etter M.D. Type II pneumocyte hypertrophy without activation of surfactant biosynthesis after partial pneumonectomy. Am. J. Physiol. 264:1993;L153-L159.
21. Clement A., Campisi J., Farmer S.R., Brody J.S. Constitutive expression of growth-related mRNAs in proliferating and nonproliferating lung epithelial cells in primary culture; evidence for growth-dependent translational control. Proc. Natl. Acad. Sci. USA. 87:1990;318-322.
22. Uhal B.D. A flow cytometric study of the type II pneumocyte cell cycle in vivo and in vitro. Cytometry. 15:1994;46-52.
23. Moss J., Vaughn M. ADP-ribosylation of guanyl nucleotide-binding regulatory proteins by bacterial toxins. Adv. Enzymol. 61:1990;303-378.
24. Pastan I.H., Johnson G.S., Anderson W.B. Role of cyclic nucleotides in growth control. Annu. Rev. Biochem. 44:1975;491-522.
25. Tsang B.K., Rixon R.H., Whitfield J.F. A possible role for cAMP in the initiation of DNA synthesis by isoproterenol-stimulated parotid gland cells. J. Cell. Physiol. 10:1980;19-26.
26. Lamy F., Roger P.P., Lecocq R., Dumont J.E. Differential protein synthesis in the induction of thyroid cell proliferation. Eur. J. Biochem. 155:1986;265-272.
27. Dumont J.E., Jauniaux J.C., Roger P.P. The cyclic AMP-mediated stimulation of cell proliferation. Trends Biochem. Sci. 14:1989;67-71.
28. Wu J., Dent P., Jelinek T., Wolfman A., Weber M.J., Sturgill T.W. Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′-5′-monophosphate. Science. 262:1993;1065-1069.
29. Cook S.J., McCormick F. Inhibition by cAMP of ras-dependent activation of raf. Science. 262:1993;1069-1072.
30. Aksamit R.R., Backlund P.S., Cantoni G.L. Cholera toxin inhibits chemotaxis by a cAMP-independent mechanism. Proc. Natl. Acad. Sci. USA. 82:1985;7475-7479.
31. Francis M.L., Ryan J., Jobling M.G., Holmes R.K., Moss J., Mond J.J. Cyclic AMP-independent effects of cholera toxin on B-cell activation. J. Immunol. 148:1992;1999-2005.
32. Qureshi S.A., Alesandropoulos K., Joseph C.K., Spangler R., Foster D.A. Cholera toxin induces expression of the immediate-early response gene JE via a cyclic AMP-independent signaling pathway. Mol. Cell. Biol. 11:(1):1991;102-107.
33. Kaur G., Viallet J., Laborda J., Blair O., Gazdar A.F., Minna J.D., Sausville E.A. Growth inhibition by cholera toxin of human lung carcinoma cell lines: correlation with GM1 ganglioside expression. Cancer Res. 52:1992;3340-3346.
34. Mitsui H., Iwamori M., Hashimoto N., Yamada H., Ikeda Y., Toda G., Kurokawa K., Nagai Y. The B-subunit of cholera toxin enhances DNA synthesis in rat hepatocytes induced by insulin and epidermal growth factor. Biochem. Biophys. Res. Commun. 174:1991;372-378.
35. Milani D., Minozzi M.C., Petrelli L., Guidolin D., Skaper S.D., Spoerri P.E. Interaction of ganglioside GM1 with the B subunit of cholera toxin modulates intracellular free calcium in sensory neurons. J. Neurosci. Res. 33:1992;466-475.
36. Dixon S.J., Stewart D., Grinstein S., Spiegel S. Transmembrane signaling of the B-subunit of cholera toxin: increased cytoplasmic free calcium in rat lymphocytes. J. Cell Biol. 105:1987;1153-1161.
37. Spiegel S., Panagiotopoulos C. Mitogenesis of 3T3 fibroblasts induced by endogenous gangliosides is not mediated by cAMP, protein kinase C or phosphoinositide turnover. Exp. Cell Res. 177:1988;417-427.
38. Spiegel S. Inhibition of protein kinase C-dependent cell proliferation by interaction of endogenous ganglioside GM1 with the B-subunit of cholera toxin. J. Biol. Chem. 264:1989;16512-16517.
39. Moore J.P., Todd J., Hesketh T.R., Metcalfe J.C. c-fos and c-myc gene activation, ionic signals and DNA synthesis in thymocytes. J. Biol. Chem. 261:1986;8158.
40. Spiegel S., Fishman P.H. Gangliosides as bimodal regulators of cell growth. Proc. Natl. Acad. Sci. USA. 84:1987;141-147.