Potential role of maternal progesterone in the sexual differentiation of the brain

Endocrinology

Volumn 139, Issue 8, 1998, Pages 3658-3661

  Wagner, Christine K ^a   Nakayama, Ann Y ^a   De Vries, Geert J ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROGESTERONE; PROGESTERONE RECEPTOR; TESTOSTERONE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; FEMALE; FETUS; MALE; MEDIAL PREOPTIC AREA; MOTHER; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; SEX DIFFERENTIATION;

EID: 0031730592     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.8.6223     Document Type: Article

References (23)

1. Arnold, AP, Gorski, RA 1984 Gonadal steroid induction of structural sex differences in the central nervous system. Ann. Rev. Neurosci. 7:413-442
2. Breedlove, SM 1992 Sexual dimorphism in the vertebrate nervous system J. Neurosci. 12:4133-4142
3. Peppe, GJ Rothchild, I 1972 The effect of hypophysectomy on day 12 of pregnancy on the serum progesterone level and time of parturition in the rat. Endocrinology 91:1380-1385
4. Sanyal, MKJ 1978 Secretion of progesterone during gestation in the rat. Endocrinology 79:179-190
5. C.E. Martin, CE Cake, MH Hartman, PE Cook, IF 1977 Relationship between foetal corticosteroids, maternal progesterone and parturition in the rat. Acta Endocrinology (Kbh) 84:167-176
6. Weisz, J Ward, IL 1980 Plasma testosterone and progesterone titers of pregnant rats, their male and female fetuses and neonatal offspring Endocrinology 106:306-316
7. Quattropani, SL Weisz, J 1973 Conversion of progesterone to estrone and estradiol in vitro by the ovary on the infantile rat in relation to the development of its interstitial tissue. Endocrinology 93:1269-1276
8. Schlegel, RJ Farias, E Russo, NC Moore, JR Gardner, LI 1967 Structural changes in the fetal gonads and gonaducts during maturation of an enzyme, steroid 3B-ol-dehydrogenase, in the gonads, adrenal cortex and placenta of fetal rats. Endocrinology 81:565-572
9. 17-20lyase, and P450 aromatase in fetal mouse gonads. Endocrinology 135:262-268
10. Kato, J and Onouchi, T 1983 Progestin receptors in female rat brain and hypophysis in the development from fetal to postnatal stages. Endocrinology 113:29-36
11. Kato, J Hirata, S Nozawa, A Mouri, N 1993 The ontogeny of gene expression of progestin receptors in the female rat brain. J. Steroid Biochem. Molec. Biol. 47:173-182
12. Traish, AM Wotiz, HH 1990 Monoclonal and polyclonal antibodies to human progesterone receptor peptide-(533-547) recognize a specific site in unactivated (8S) and activated (4S) progesterone receptor and distinguish between intact and proteolyzed receptors. Endocrinology 127:1167-1175.
13. Altman, J Bayer, SA 1995 Atlas of Prenatal Rat Brain Development. CRC Press, Boca Raton 485.
14. Sachs, BD Meisel, RL 1994 The physiology of male sexual behavior. In: Knobil, E Neill, J (eds) The Physiology of Reproduction. Raven Press, New York, 3-75
15. Numan, M 1994 Maternal behavior. In: The Physiology of Reproduction. Knobil, E Neill, J (eds) The Physiology of Reproduction. Raven Press, New York, 223-283
16. Brown, TJ Clark, AS MacLusky, NJ 1987 Regional sex differences in progestin receptor induction in the rat hypothalamus: effects of various doses of estradiol benzoate. J. Neurosci. 7:2529-2536
17. Hull, EM 1981 Effect of neonatal exposure to progesterone on sexual behavior of male and female rats. Physiol. Behav. 26:401-405
18. Hull, EM Franz, JR Snyder, AM Nishita, JK 1980 Perinatal progesterone and learning, social and reproductive behavior in rats. Physiol. Behav. 24:251-256
19. Wagner, CK Kinsley, C Svare, B 1986 Postpartum aggression is elevated following prenatal progesterone exposure. Horm.Behav. 20:212-221
20. Reinisch, JM Karow, WG 1977 Prenatal exposure to synthetic progestins and estrogens: effects on human development. Arch. Sex. Behav. 6:257-288
21. Reinisch, JM 1981 Prenatal exposure to synthetic progestins increases the potential for aggression in humans. Science 211:1171-1173
22. Dalton, K. 1976 Prenatal progesterone and educational attainments. Br. J. Psychiat. 129:438-442
23. Ehrhardt, AA Gristani, GC Meyer-Bahlburg, HFL 1977 Prenatal exposure to medroxyprogesterone acetate (MPA) in girls. Psychoneuroendocrinol. 2:391-398