Correlation of increased mortality with the suppression of radiation-inducible microsomal epoxide hydrolase and glutathione S-transferase gene expression by dexamethasone: Effects on vitamin C and E-induced radioprotection

Biochemical Pharmacology

Volumn 56, Issue 10, 1998, Pages 1295-1304

  Nam, Seon Young ^a   Cho, Chul Koo ^b   Kim, Sang Geon ^a  

^a Duksung Women's University   (South Korea)

^b Korea Cancer Center Hospital   (South Korea)

Author keywords

Dexamethasone; Glutathione S transferase; Microsomal epoxide hydrolase; Radioprotective effect; Vitamin C; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; DEXAMETHASONE; EPOXIDE HYDROLASE; GLUCOCORTICOID; GLUTATHIONE TRANSFERASE; MESSENGER RNA; OLTIPRAZ;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; GAMMA IRRADIATION; GENE EXPRESSION; IONIZING RADIATION; IRRADIATION; LIVER MICROSOME; MALE; MESSENGER RNA SYNTHESIS; MORTALITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RADIATION PROTECTION; RAT; SURVIVAL RATE; WHOLE BODY RADIATION;

ANIMALS; ASCORBIC ACID; DEXAMETHASONE; EPOXIDE HYDROLASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE TRANSFERASE; MICE; MICE, INBRED ICR; MICROSOMES, LIVER; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; VITAMIN E;

EID: 0031730369     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00203-2     Document Type: Article

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