Thyrocyte class I and class II upregulation is a secondary phenomenon and does not contribute to the pathogenesis of autoimmune thyroid disease

Thyroid

Volumn 8, Issue 9, 1998, Pages 755-763

  Yue, Shi Jun ^a   Enomoto, Tetsuya ^a   Matsumoto, Yoshiaki ^a   Kawai, Keisuke ^a   Volpé, Robert ^a,b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ANTIGEN; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; THYROID ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNE DISEASE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DISEASE ASSOCIATION; GRAVES DISEASE; HASHIMOTO DISEASE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THYROID DISEASE; XENOGRAFT;

EID: 0031729674     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/thy.1998.8.755     Document Type: Article

References (25)

1. Hanafusa T, Pujol-Borrell R, Chiovato L, Russell RC, Doniach D, Botazzo GF 1983 Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease: Relevance for autoimmunity. Lancet 2:1111-1115.
2. Bottazzo GF, Pujol-Borrell R, Hanafusa T, Feldmann M 1983 Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity. Lancet 2:1115-1119.
3. Todd I, Londei M, Pujol-Borrell R, Mirakian R, Feldmann M, Bottazzo GF 1986 HLA D/DR expression on epithelial cells: The finger on the trigger? Ann NY Acad Sci 475:241-250.
4. Weetman AP 1995 Review: Antigen presentation in the pathogenesis of autoimmune endocrine disease. J Autoimmunity 8:305-312.
5. Kohn LD, Giuliani C, Montani V, Napolitano G, Ohmori M, Ohta M, Saji M, Schuppen F, Shong MH, Suzuki K, Taniguchi SI, Yano K, Singer DS 1995 Anti-receptor immunity. In: Rayner D, Champion BR, (eds). Thyroid Autoimmunity. RG Landes Publishers, Austin, Texas, pp 115-170.
6. Kawai K, Enomoto T, Fornasier V, Resetkova E, Volpé R 1997 Differential effects of human Interferon alpha and interferon gamma on xenografted human thyroid tissue in severe combined immunodeficient mice and nude mice. Proc Assoc Am Physicians 109:126-135.
7. Kirchner H 1984 Interferons, a group of multiple lymphokines. Springer Semin Immunopathol 7:255-261.
8. Volpé R, Akasu F, Morita T, Yoshikawa N, Resetkova E, Arreaza G, Mukuta T 1993 New animal models for human autoimmune thyroid disease. Xenografts of human thyroid tissue in severe combined immunodeficient (SCID) and nude mice. Horm Metab Res 25:623-627.
9. Schuler W, Bosma MJ 1989 Nature of the SCID defect: A defective VDJ recombinase system. Curr Top Microbiol Immunol 152:55-62.
10. Smeds S, Jortso E, Anderberg B, Boeryd B, Ericson LE, Moine J, Persliden J, Tegler L 1984 Ultrastructural morphology and evidence of iodine uptake and protein synthesis in normal human thyroid transplants in nude mice. J Endocrinol Invest 7:569-578.
11. Usadel KH, Paschke R, Teuber J, Schwedes U 1987 Heterotransplantation of autoimmune thyroid tissue to nude mice as a tool for in vivo autoimmune research. In: Pinchera A, Ingbar SH, McKenzie JM, Fenzi GF (eds) Thyroid Autoimmunity. Plenum Press, New York, pp 207-210.
12. Fentiman IS, Thomas BS, Balkwill PR, Rubens RD, Hayward JL 1985 Primary hypothyroidism associated with interferon therapy of breast cancer. Lancet 1:1166.
13. Burman P, Totterman TH, Oberg K, Karlsson FA 1986 Thyroid autoimmunity in patients on long term therapy with leukocyte-derived interferon. J Clin Endocrinol Metab 63:1066-1090.
14. Lisker-Melman M, Bisceglie AM, Usala SJ, et al 1992 Development of thyroid disease during therapy of chronic viral hepatitis with interferon alpha. Gastroenterology 102:2155-2160.
15. Arreaza G, Yoshikawa N, Mukuta T, Resetkova E, Barsouk A, Nishikawa M, Muellim C, Miller N, Jamieson C, Volpé R 1995 Expression of intercellular adhesion molecule-1 (ICAM-1) on human thyroid cells from patients with autoimmune thyroid disease: Study of thyroid xenografts in nude and severe combined immunodeficient mice and treatment with FK506. J Clin Endocrinol Metab 8:3724-3731.
16. Schuppert F, Reiser M, Heldin NE, Ede S, Scheuman GFW, Dralle H, Von-Zur-Muhlin A 1994 TSH receptor and leucocyte adhesion molecules in autoimmune thyroid disease: A study of their gene expression by Northern blot analysis and in situ hybridization. Acta Endocrinolog (Copenh) 131:480-488.
17. Weetman AP, Freeman M, Borysiewicz LK, Makgoba MW 1990 Functional analysis of intercellular adhesion molecule1 expressing human thyroid cells. Eur J Immunol 20:271-275.
18. Shimojo N, Kohno Y, Yamaguchi KI, Kikuoka SI, Hoshioka A, Niimi H, Hirai A, Tamura Y, Saito Y, Kohn LD, Tahara K 1996 Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule. Proc Natl Acad Sci USA 93:11074-11079.
19. Tandon N, Metcalfe RA, Barnett D, Weetman AP 1994 Expression of the costimulatory molecule B7/BB1 in autoimmune thyroid disease. Q J Med 87:231-236.
20. Teng WP, You X, Shan ZY, Volpé R 1997 Effects of human interferon-alpha on human peripheral blood mononuclear cells and human thyrocytes [abstract]. Thyroid 7:(suppl 1):46.
21. Janeway CA Jr, Bottomly K 1994 Signals and signs for lymphocyte responses. Cell 76:275-285.
22. Matsuoka N, Eguchi K, Kawakami A, Tsuboi M, Nakamura H, Kimura H, Ishikawa N, Ito K, Nagataki S 1996 Lack of B7-1/BB1 and B7-2/B70 expression on thyrocytes of patients with Graves' disease. Delivery of costimulatory signals from bystander professional antigen presenting cells. J Clin Endocrinol Metab 81:4137-4144.
23. Weetman AP 1992 Autoimmune thyroiditis. Predisposition and pathogenesis. Clin Endocrinol 36:307-323.
24. Weetman AP 1996 Recent progress in thyroid autoimmunity: An overview for the clinician. Thyroid Today 19(2):l-9.
25. Kung AWC, Jones BM, Lai CL 1990 Effects of Interferon gamma therapy on thyroid function. T lymphocyte subpopulations and induction of autoantibodies. J Clin Endocrinol Metab 71:1230-1234.