Preponderance of slightly deleterious polymorphism in mitochondrial DNA: Nonsynonymous/synonymous rate ratio is much higher within species than between species

Molecular Biology and Evolution

Volumn 15, Issue 11, 1998, Pages 1499-1505

  Hasegawa, Masami ^a   Cao, Ying ^a   Yang, Ziheng ^a,b  

^a INSTITUTE OF STATISTICAL MATHEMATICS   (Japan)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Codon substitution; Hominoids; Likelihood ratio test; Mitochondrial DNA; Nonsynonymous synonymous rate ratio; Slightly deleterious mutations

Indexed keywords

MITOCHONDRIAL DNA; ADENOSINE TRIPHOSPHATASE; MT ATP6 PROTEIN, HUMAN; MT-ATP6 PROTEIN, HUMAN; NADH DEHYDROGENASE SUBUNIT 4; OXIDOREDUCTASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ARTICLE; CHIMPANZEE; CODON; DNA POLYMORPHISM; EVOLUTION; GENETIC CODE; GENETIC CONSERVATION; GENOME; GORILLA; HOMINID; HUMAN; MUTATION RATE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; SPECIES DIFFERENCE; AMINO ACID SUBSTITUTION; ANIMAL; BIOLOGICAL MODEL; COMPARATIVE STUDY; ENZYMOLOGY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENETICS; MITOCHONDRION; MOLECULAR EVOLUTION; MUTAGENESIS; PAN TROGLODYTES; STATISTICAL MODEL;

HOMINIDAE; HOMO; PAN TROGLODYTES;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SUBSTITUTION; ANIMALS; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX I; EVOLUTION, MOLECULAR; GORILLA GORILLA; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MODELS, GENETIC; MODELS, STATISTICAL; MUTAGENESIS; NADH DEHYDROGENASE; NADH, NADPH OXIDOREDUCTASES; PAN TROGLODYTES; POLYMORPHISM, GENETIC; SPECIES SPECIFICITY; VARIATION (GENETICS);

EID: 0031729188     PISSN: 07374038     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.molbev.a025877     Document Type: Article

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