Low calcium abolishes tip links and alters relative stereocilia motion in chick cochlear hair cells

Hearing Research

Volumn 124, Issue 1-2, 1998, Pages 69-77

  Duncan, R Keith ^a   Dyce, Orville H ^b   Saunders, James C ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Hd Neck Surg Thomas Jefferson U   (United States)

Author keywords

Auditory; Calcium; Chick; Micromechanics; Stereocilium; Tip link

Indexed keywords

CALCIUM ION; EGTAZIC ACID;

ANIMAL CELL; ARTICLE; AUDITORY SYSTEM; CALCIUM TRANSPORT; CHICKEN; COCHLEA; HAIR CELL; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SIGNAL TRANSDUCTION; STEREOCILIUM;

ANIMALS; ANIMALS, NEWBORN; CALCIUM; CHICKENS; CILIA; HAIR CELLS; MICROSCOPY, ELECTRON, SCANNING; MOTION;

EID: 0031728142     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5955(98)00118-X     Document Type: Article

References (31)

1. Assad J.A., Shepherd G.M.G., Corey D.P. Tip-link integrity and mechanical transduction in vertebrate hair cells. Neuron. 7:1991;985-994.
2. Comis S.D., Pickles J.O., Osborne M.P. Osmium tetroxide postfixation in relation to the cross linkage and spatial organization of stereocilia in the guinea-pig cochlea. J. Neurocytol. 14:1985;113-130.
3. Duncan R.K., Hernandez H.N., Saunders J.C. Relative stereocilia motion of chick cochlear hair cells during high-frequency water-jet stimulation. Aud. Neurosci. 1:1995;321-329.
4. Duncan R.K., Grant J.W. A finite-element model of inner ear hair bundle micromechanics. Hear. Res. 104:1997;15-26.
5. Furness D.N., Hackney C.M. Cross-links between stereocilia in the guinea pig cochlea. Hear. Res. 18:1985;177-188.
6. Furness D.N., Hackney C.M. High-resolution scanning-electron microscopy of stereocilia using the osmium-thiocarbohydrazide coating technique. Hear. Res. 21:1986;243-249.
7. Goodyear R., Richardson G. Differential glycosylation of auditory and vestibular hair bundle proteins revealed by peanut agglutinin. J. Comp. Neurol. 345:1994;267-278.
8. Guttenplan M., Jenkins O.H., Saunders J.C. Structural changes in hair cells after incubation in tissue culture medium. Hear. Res. 43:1989;47-54.
9. Hackney C.M., Furness D.N., Benos D.J., Woodley J.F., Barratt J. Putative immunolocalization of the mechanoelectrical transduction channels in mammalian cochlear hair cells. Proc. R. Soc. Lond. B. 248:1992;215-221.
10. Hackney, C.M., Furness, D.N., 1995a. Hair cell ultrastructure and mechanotransduction: morphological effects of low extracellular calcium levels on stereociliary bundles in the turtle cochlea. In: C. Flock, D. Ottoson, and M. Ulfendahl (Eds.), Active Hearing, Elsevier, New York, NY, pp. 103-111.
11. Hackney C.M., Furness D.N. Mechanotransduction in vertebrate hair cells: structure and function of the stereociliary bundle. Am. J. Physiol. 268:1995;C1-C13.
12. Hacohen N., Assad J., Smith W., Corey D. Regulation of tension on hair cell transduction channels: displacement and calcium dependence. J. Neurosci. 9:1989;3988-3997.
13. Howard J., Ashmore J.F. Stiffness of sensory hair bundles in the sacculus of the frog. Hear. Res. 23:1986;93-104.
14. Howard J., Roberts W.M., Hudspeth A.J. Mechanoelectrical transduction by hair cells. Annu. Rev. Biophys. Chem. 17:1988;99-124.
15. Howard J., Hudspeth A.J. Compliance of the hair bundle associated with gating of mechanoelectrical transduction by the bullfrog's saccular hair cell. Neuron. 1:1988;189-199.
16. Husbands, J., Kurian, R., Steinberg, S.A., Saunders, J.C., 1998. Tip-link integrity on chick tall hair cells following exposure to intense sound. Abstracts of the 21st Midwinter Research Meeting, Association for Research in Otolaryngology, 199.
17. Jacobs R.A., Hudspeth A.J. Ultrastructural correlates of mechanoelectrical transduction in hair cells of the bullfrog's internal ear. Cold Spring Harbor Symp. Quant. Biol. 55:1990;547-561.
18. Jaramillo F., Hudspeth A.J. Displacement-clamp measurement of the forces exerted by gating springs in the hair bundle. Proc. Natl. Acad. Sci. USA. 90:1993;1330-1334.
19. Little K.F., Neugebauer D.-Ch. Interconnections between the stereovilli of the fish inner ear. II. Systematic investigation of saccular hair bundles from Rutilus (Teleostei). Cell Tissue Res. 242:1985;427-432.
20. 2+ concentration on hair-bundle stiffness and gating-spring integrity in hair cells. Proc. Natl. Acad. Sci. USA. 94:1997;11923-11928.
21. Pae S.S., Saunders J.C. Intra- and extracellular calcium modulates stereocilia stiffness on chick cochlear hair cells. Proc. Natl. Acad. Sci. USA. 91:1994;1153-1157.
22. Pickles J.O. A model for the mechanics of the stereociliar bundle on acousticolateral hair cells. Hear. Res. 68:1993;159-172.
23. Pickles J.O., Corey D.P. Mechanoelectric transduction by hair cells. Trends Neurosci. 15:1992;254-259.
24. Pickles J.O., Comis S.D., Osborne M.P. Cross-links between stereocilia in the guinea-pig organ of Corti, and their possible relation to sensory transduction. Hear. Res. 15:1984;103-112.
25. Pickles J.O., Brix J., Comis S.D., Gleich O. The organization of tip links and stereocilia on hair cells of bird and lizard basilar papillae. Hear. Res. 41:1989;31-41.
26. Pickles J.O., von Perger M., Rouse G.W., Brix J. The development of links between stereocilia in hair cells of the chick basilar papilla. Hear. Res. 54:1991;153-163.
27. Saunders J.C., Szymko Y.M. The design, calibration, and use of a water microjet for stimulating hair cell sensory hair bundles. J. Acoust. Soc. Am. 86:1989;1797-1804.
28. Szymko Y.M., Dimitri P.S., Saunders J.C. Stiffness of hair bundles in the chick cochlea. Hear. Res. 59:1992;241-249.
29. Tanaka K., Smith C. Structure of the chicken's inner ear: SEM and TEM study. Am. J. Anat. 153:1978;251-271.
30. Tilney L.G., Saunders J.C. Actin filaments, stereocilia, and hair cells of the bird cochlea. I. Length, number, width and distribution of stereocilia of each hair cell are related to the position of the hair cell on the cochlea. J. Cell Biol. 96:1983;807-821.
31. Zhao Y.D., Yamoah E.N., Gillespie P.G. Regeneration of broken tip links and restoration of mechanical transduction in hair cells. Proc. Natl. Acad. Sci. USA. 94:1996;15469-15474.