Modification of intrinsic AV-nodal properties by magnesium in combination with glucose, insulin, and potassium (GIK) during chronic atrial fibrillation

Journal of Electrocardiology

Volumn 31, Issue 4, 1998, Pages 281-292

  Ingemansson, M P ^a,b   Carlson, J ^a   Olsson, S B ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Ambulatory ECG recording; Atrial fibrillation; AV node; Fast pathway; Magnesium; RR interval; Slow pathway

Indexed keywords

GLUCOSE; INSULIN; MAGNESIUM; MAGNESIUM SULFATE; POTASSIUM;

ADULT; AGED; ARTICLE; ATRIOVENTRICULAR CONDUCTION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HEART ATRIOVENTRICULAR NODE; HEART ATRIUM FIBRILLATION; HEART ELECTROPHYSIOLOGY; HEART RATE; HIS BUNDLE; HUMAN; PRIORITY JOURNAL; RR INTERVAL;

EID: 0031726326     PISSN: 00220736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-0736(98)90013-9     Document Type: Article

References (38)

1. Moe GK, Preston JB, Burlington H: Physiologic evidence for a dual A-V transmission system. Circ Res 4:357-375, 1956
2. Mendez C, Moe GK: Demonstration of a dual A-V nodal conduction system in the isolated rabbit heart preparation. Circ Res 19:378-393, 1966
3. Rosen KM, Denes P, Wu D, Dhingara C: Electrophysiological diagnosis and manifestation of dual A-V nodal pathways. p. 453-466. In: Wellens HJJ, Lie KI, Janse MJ (eds). The Conduction System of the Heart. The Hague: Martinus Nijhoff, 1978
4. Janse MJ: The role of the atrioventricular node in atrial fibrillation. pp. 127-140. In: Olsson SB, Allessie MA, Campbell RWF (eds). Atrial Fibrillation: Mechanisms and Therapeutic Strategies. Armonk, NY: Futura Publishing Co, 1994
5. Page RL, Wharton JM, Prystowsky EN: Effect of continuous vagal enhancement on concealed conduction and refractoriness within the atrioventricular node. Am J Cardiol 77:260-265, 1996
6. Zipes DP, Mendez C, Moe GK: Evidence for summation and voltage dependency in rabbit atrioventricular nodal fibers. Circ Res, 32:170-177, 1973
7. Prystowsky EN, Page RL: Electrophysiology and autonomic influences of the human atrioventricular node. pp. 259-277. In: Electrophysiology of the Sino-Atrial and Atrioventricular Nodes. New York: Alan R. Liss, Inc, 1988
8. Janse MJ, Van Capelle FJL, Anderson RH, et al: Electrophysiology and structure of the atrioventricular node of isolated rabbit heart. Am J Physiol 243H: 754-760, 1982
9. Janse MJ: Influence of the direction of atrial wave front on AV nodal transmission in isolated hearts of rabbits. Circ Res 25:439-449, 1969
10. Amat-y-Leon F, Denes P, Wu RJ: Effects of atrial pacing site on atrial and atrioventricular nodal function. Br Heart J 37:576-582, 1975
11. Batsford WP, Akhtar M, Caracta AR: Effect of atrial stimulation site on the electrophysiological properties of the atrioventricular node in man. Circulation 50:283-292, 1974
12. Olsson SB, Cai N, Dohnal M, Talwar KK: Noninvasive support for and characterization of multiple intranodal pathways in patients with mitral valve disease and atrial fibrillation. Eur Heart J 7:320-333, 1986
13. Olsson SB, Cai N, Dohnal M, William-Olsson G: Effect of crista terminalis myotomy on the AV nodal function in atrial fibrillation. pp. 249-261. In: Attuel P, Coumel P, Janse MJ (eds). The Atrium in Health and Disease. Mount Kisco, NY: Futura Publishing Company, Inc, 1989
14. Cai N, Dohnal M, Olsson SB: Methodological aspects of the use of heart rate stratified RR interval histograms in the analysis of atrioventricular conduction during atrial fibrillation. Cardiovasc Res 21:455-462, 1987
15. Gaitanidou S, Rokas S, Chatzidou S, et al: The presence of dual atrioventricular node physiology in patients with chronic atrial fibrillation. Clinical implications. Eur Heart J 18:P1797, 1997
16. Toivonen L, Radish A, Kou W, Morady F: Determinants of the ventricular rate during atrial fibrillation. JACC 16:1194-1200, 1990
17. Mcguire MA, De Bakker JMT, Vermeulen JT, et al: Atrioventricular junctional tissue: Discrepancy between histological and electrophysiological characteristics. Circulation 94:571-577, 1996
18. Tieleman RG, De Langen CDJ, Van Gelder IC, et al: Verapamil reduces tachycardia-induced electrical remodeling of the atria. Circulation 95:1945-1953, 1997
19. Tieleman RG, Crijns HJGM, Van Gjelder IC, et al: A clinical illustration of reduction of electrical remodeling by the use of intracellular calcium lowering drugs during AF. PACE 20(A):1142, 1997
20. Mary-Rabine L, Albert A, Pham TD, et al: The relationship of human atrial cellular electrophysiology to clinical function and ultrastructure. Circ Res 52:188-199, 1983
21. Ten Eick RE, Singer DH: Electrophysiological properties of diseased human atrium. I. Low diastolic potential and altered cellular response to potassium. Circ Res 44:545-557, 1979
22. Rosen MR: Editorial comments. pp. 163-169. In: DiMarco JP, Prystowsky EN (eds): Atrial Arrhythmias: State of the Art. Armonk, NY: Futura Publishing Co, Inc, 1995
23. 4 and glucose, insulin and potassium (GIK) on atrial conduction during the first 12 hours after DC-conversion of chronic atrial fibrillation. (Submitted), 1998
24. 4 alone and in combination with the hyperpolarising solution (GIK) prolongs the atrial cycle length in chronic atrial fibrillation. J Cardiovasc Pharmacol (in press), 1998
25. Rasmussen HS, Thomsen PE: The electrophysiological effects of intravenous magnesium on human sinus node, atrioventricular node, atrium, and ventricle. Clin Cardiol 12(2):85-90, 1989
26. Sodi-Pallares D, Bisteni A, Medrano GA, Testelli MR, De Micheli A. The polarizing treatment of acute myocardial infarction. Dis Chest 4:424-432, 1963
27. Brugada P, Roy D, Weiss J, Dassen WRM, Wellens HJJ: Dual atrioventricular nodal pathways and atrial fibrillation. PACE 7:240-247, 1984
28. Keim S, Werner P, Jazayeri M, Akhtar M, Tchou P: Localisation of the fast and slow pathways in atrioventricular nodal reentrant tachycardia by intraoperative ice mapping. Circulation 86:919-925, 1992
29. Strickberger SA, Weiss R, Daoud BG, et al: Ventricular rate during atrial fibrillation before and after slow-pathway ablation. Circulation 94:1023-1026, 1996
30. Haissaguerre M, Gaita F, Fischer B, et al: Elimination of atrioventricular nodal reentrant tachycardia using discrete slow potentials to guide application of radiofrequency energy. Circulation 85:2162-2175, 1992
31. Langberg JJ: Radiofrequency catheter ablation of AV nodal reentry: The anterior approach. PACE 16:615-622, 1993
32. Duckeck W, Engelstein ED, Kuck KH: Radiofrequency current therapy in atrial tachyarrhythmias: Modulation versus ablation of AV nodal conduction. PACE 16:629-636, 1993
33. Munk AA, Adjemian RA, Zhao J, Ogbaghebriel A, Shrier A: Electrophysiological properties of morphologically distinct cells isolated from the rabbit atrioventricular node. J Physiol (Lond) 15:801-818, 1996
34. Hess P, Lansman JB, Tsien RW: Calcium channel selectivity for divalent and monovalent actions. J Gen Physiol 88:293-318, 1986
35. Biermans G, Vereecke J, Carmeliet E: The mechanism of the inactivation of the inward-rectifying K current during hyperpolarizing steps in guinea-pig ventricular myocytes. Pflügers Arch 410:604-613, 1987
36. Zhang S, Sawanobori T, Adaniya H, Hirano Y, Hiraoka M: Dual effects of external magnesium on action potential duration in guinea pig ventricular myocytes. J Am Physiol Soc H2321-H2328, 1995
37. Holm M, Johansson R, Brandt J, Luhrs C, Olsson SB: Epicardial right atrial free wall mapping in chronic atrial fibrillation. Documentation of repetitive activation with a focal spread-a hitherto unrecognised phenomenon in man. Eur Heart J 18: 290-310, 1997
38. Gerstenfeld BP, Sahakian AV, Swiryn S: Evidence for transient linking of atrial excitation during atrial fibrillation in humans. Circulation 86:375-382, 1992