An A/G-rich motif in the rat fibroblast growth factor-2 gene confers enhancer activity on a heterologous promoter in neonatal rat cardiac myocytes

Molecular and Cellular Biochemistry

Volumn 188, Issue 1-2, 1998, Pages 169-176

  Detillieux, Karen A ^a   Meyers, Adrienne F A ^a   Meij, Johanna T A ^a   Cattini, Peter A ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

FGF 2; Gene transfer; HSV thymidine kinase promoter; Transcription

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ATRIAL NATRIURETIC FACTOR; FIBROBLAST GROWTH FACTOR 2; LUCIFERASE; NUCLEAR PROTEIN; OLIGONUCLEOTIDE; PHENYLEPHRINE; THYMIDINE KINASE; VIRUS ENZYME;

ANIMAL CELL; BASE PAIRING; COMPLEX FORMATION; CONFERENCE PAPER; CONTROLLED STUDY; DNA FLANKING REGION; ENHANCER REGION; GEL MOBILITY SHIFT ASSAY; GENE FUNCTION; GENE FUSION; GENE STRUCTURE; GENE TRANSFER; GENETIC TRANSFECTION; GLIOMA; HEART MUSCLE CELL; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; MOLECULAR CLONING; NEWBORN; NEWBORN PERIOD; NONHUMAN; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; RAT; TISSUE SPECIFICITY; TUMOR CELL;

ADENOSINE; ANIMALS; ANIMALS, NEWBORN; BASE COMPOSITION; BASE SEQUENCE; CELLS, CULTURED; ENHANCER ELEMENTS (GENETICS); FIBROBLAST GROWTH FACTOR 2; GUANOSINE; HUMANS; MOLECULAR SEQUENCE DATA; MYOCARDIUM; NUCLEAR PROTEINS; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; REPETITIVE SEQUENCES, NUCLEIC ACID; TUMOR CELLS, CULTURED;

ANIMALIA; HERPES; RODENTIA; SIMPLEXVIRUS;

EID: 0031725658     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006886307083     Document Type: Conference Paper

References (26)

1. Sugi Y, Sasse J, Lough J: Inhibition of precardiac mesoderm cell proliferation by antisense oligodeoxynucleotide complementary to fibroblast growth factor-2 (FGF-2). Dev Biol 157: 28-37, 1993
2. Mima T, Ueno H, Fischman DA, Williams LT, Mikawa T: Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development. Proc Natl Acad Sci USA 92: 467-471, 1995
3. Clarke MS, Caldwell RW, Chiao H, Miyake K, McNeil PL: Contraction-induced cell wounding and release of basic fibroblast growth factor. Circ Res 76: 927-934, 1995
4. Kaye D, Pimental D, Prasad S, Maki S, Berger HJ, McNeil PL, Smith TW, Kelly RA: Role of transiently altered sarcolemmal membrane permeability and basic fibroblast growth factor release in the hypertrophie response of adult rat ventricular myocytes to increased mechanical activity in vitro. J Clin Invest 97: 281-291, 1996
5. Unger EF, Banai S, Shou M, Lazarous DF, Jaklitsch MT, Scheinowitz M, Correa R, Ninbeil C, Epstein SE: Basic fibroblast growth factor enhances myocardial collateral flow in a canine model. Am J Physiol 266 (Heart Circ Physiol 35): H158-H1595, 1994
6. Lazarous DF, Scheinowitz M, Shou M, Hodge E, Majanayagam MAS, Hunsberger S, Robinson Jr WG, Stiber JA, Correa R, Epstein SE, Unger EF: Effects of chronic systemic administration of basic fibroblast growth factor on collateral development in the canine heart. Circulation 91: 145-153, 1995
7. Fox JC, Shanley JR: Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells. J Biol Chem 271: 12578-12584, 1996
8. Padua RR, Sethi R, Dhalla NS, Kardami E: Basic fibroblast growth factor is cardioprotective in ischemia-reperfusion injury. Mol Cell Biochem 143: 129-135, 1995
9. Padua RR, Sethi R, Davey-Forgie SE, Lui L, Dhalla N, Kardami E: Cardioprotection and basic fibroblast growth factor. In: N.S. Dhalla, P.K. Singal, R.E. Beamish (eds). Heart Hypertrophy and Failure. Kluwer Academic Publishers, Boston, 1996, pp 501-518.
10. Shibata F, Baird A, Florkiewicz RZ: Functional characterization of the human basic fibroblast growth factor promoter. Growth Factors 4: 277-287, 1991
11. Pasumarthi KBS, Jin Y, Cattini PA: Cloning of the rat fibroblast growth factor-2 promoter region and its response to mitogenic stimuli in glioma C6 cells. J Neurochem 68: 898-908, 1997
12. Ueba T, Nosaka T, Takahashi JA, Shibata F, Florkiewicz RZ, Vogelstein B, Oda Y, Kikuchi H, Hatanaka M: Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastma and hepatocellular carcinoma cells. Proc Natl Acad Sci USA 91: 9009-9013, 1994
13. Biesiada E, Razandi M, Levin ER: Egr-1 activates basic fibroblast growth factor transcription. J Biol Chem 271: 18576-18581, 1996
14. 1-adrenergic receptor signaling in cardiac cells. EMBO J 12: 5131-5139, 1993
15. Pasumarthi KBS, Kardami E, Cattini PA: High and low molecular weight fibroblast growth factor-2 increase proliferation of neonatal rat cardiac myocytes but have differential effects on binucleation and nuclear morphology: Evidence for both paracrine and intracrine actions of fibroblast growth factor-2. Circ Res 78: 126-136, 1996
16. Dignam JD, Lebovitz RM, Roeder RG: Accurate transcript ion initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucl Acids Res 11: 1475-1489, 1983
17. Andrews NC, Faller DV: A rapid micropreparation technique for extraction of DNAbinding proteins from limiting numbers of mammalian cells. Nucl Acids Res 19: 2499, 1991
18. Nordeen SK: Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6: 454-458, 1988
19. Smith PK, Krohn RI, Hermansen GT, Mallia AK, Gartner FH, Fugimoto EK, Goeke NM, Olson BJ, Klenk DC: Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85, 1985
20. Baldwin AS: Analysis of sequence-specific DNA-binding proteins by the gel mobility shift assay. DNA Protein Eng Tech 2: 73-76, 1990
21. Lytras A, Cattini PA: Human chorionic somatomammotropin gene enhancer activity is dependent on the blockade of a repressor mechanism. Mol Endocrinol 8: 478-489, 1994
22. Boulikas T: Homeodomain protein binding sites, inverted repeats, and nuclear matrix attachment regions along the human β-globin gene complex. J Cell Biochem 52: 23-36, 1993
23. Kardami E, Liu L, Padua RR, Fandrich RR, Pasumarthi SKB, Cattini PA: Regulation of basic fibroblast growth factor (bFGF) and FGF receptors in the heart. Ann NY Acad Sci 752: 353-369, 1995
24. Bikfalvi A, Klein S, Pintucci G, Rifkin DB: Biological roles of fibroblast growth factor-2. Endocrine Rev 18: 26-45, 1997
25. Omitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M: Receptor specificity of the fibroblast growth factor family. J Biol Chem 271: 15292-15297, 1996
26. Sprenkle AB, Murray SE, Glembotski CC: Involvement of multiple cis-elements in basal and α-adrenergic agonist-inducible ANF transcription. Roles for serum response elements and an Sp-1-like element. Circ Res 77: 1060-1069, 1995