Valproic acid use in psychiatry: Issues in treating women of reproductive age

Journal of Psychiatry and Neuroscience

Volumn 23, Issue 4, 1998, Pages 223-228

  Kennedy, Debra ^b   Koren, Gideon ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b NONE

Author keywords

Abnormalities; Alpha fetoprotein; Drug induced; Neural tube defects; Valproic acid

Indexed keywords

ALPHA FETOPROTEIN; VALPROIC ACID;

AMNIOCENTESIS; DRUG USE; ECHOGRAPHY; HUMAN; MANIC DEPRESSIVE PSYCHOSIS; NEURAL TUBE DEFECT; PREGNANCY; PRENATAL DIAGNOSIS; PRENATAL DRUG EXPOSURE; PRENATAL SCREENING; PROTEIN BLOOD LEVEL; REVIEW; TERATOGENESIS;

ADULT; ANIMALS; ANTIMANIC AGENTS; FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS; TERATOGENS; VALPROIC ACID;

EID: 0031725331     PISSN: 11804882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (49)

1. Gerner RH, Stanton A. Algorithm for patient management of acute manic states: lithium, valproate or carbamazepine? J Clin Psychopharmacol 1992;12(Suppl 1):57S-63S.
2. Gelenberg J, Kane JM, Keller MB, Lavori P, Rosenbaum JF, Cole K, et al. Comparison of standard and low serum levels of lithium for maintenance treatment of bipolar disorder. N Engl J Med 1989;321:1489-93.
3. Keller MB, Lavori PW, Kane JM, Gelenberg AJ, Rosenbaum JF, Walzer EA, et al. Subsyndromal symptoms in bipolar disorder. A comparison of standard and low serum levels of lithium. Arch Gen Psychiatry 1992;49:371-6.
4. Phillips NI, Fowler LJ. The effects of sodium valproate on gamma butyrate metabolism and behavior in naive and ethanolamin-O-sulphate pretreated rats and mice. Biochem Pharmacol 1982;31:2257-61.
5. Chapman A, Keane PE, Meldrum BS, Simiand J, Vernieres JC. Mechanism of anticonvulsant action of valproate. Prog Neurobiol 1982;19:315-9.
6. Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Goodman LS. Gilman A. The pharmacological basis of therapeutics, 9th ed. New York: McGraw-Hill; 1996.
7. Pope HG, McElroy SL, Keck FE, Hudson IL. Valproate in the treatment of acute mania. A placebo-controlled study. Arch Gen Psychiatry 1991;48:62-8.
8. Bowden CL, Brugger AM, Swann AC, Calabrese JR, Janicak PG, Petty F, et al. Efficacy of divalproex vs lithium and placebo in the treatment of mania. JAMA 1994;271:918-24.
9. Calabrese JR, Delucci GA. Spectrum of efficacy of valproate in 55 patients with rapid-cycling bipolar disorder. Am J Psychiatry 1990;147:431-4.
10. Brown NA, Kao J, Fabro S. Teratogenic potential of valproic acid [letter]. Lancet 1980;1(8169):660-1.
11. Dalens B, Raynaud El, Gaulme J. Teratogenicity of valproic acid [letter]. J Pediatr 1980;97(2):332-3.
12. Hiilesmaa VK, Bardy AH, Granstrom ML, Teramo KA. Valproic acid during pregnancy [letter]. Lancet 1980;1(8173):883.
13. Robert H, Guibaud P. Maternal valproic acid and congenital neural tube defects [letter]. Lancet 1982;2(8304):937.
14. Lindhout D, Schmidt D. In-utero exposure to valproate and neural tube defects [letter]. Lancet 1986;1(8494):1392-3.
15. Lindhout D, Omtzigt JG, Cornel MC. Spectrum of neural-tube defects in 34 infants prenatally exposed to antiepileptic drugs. Neurology 1992;42(4 Suppl 5):111-8.
16. Van Allen MI, Kalousek DK, Chernoff GF, Juriloff D, Harris M, McGillivray BC, et al. Evidence for multi-site closure of the neural tube in humans. Am J Med Genet 1993;47:723-43.
17. Rosa FW. Spina bifida in infants of women treated with carbamazepine during pregnancy. N Engl J Med 1991;324:674-7.
18. Ardinger HH, Atkin JF, Blackston RD, Elsas LJ, Clarren SK, Livingstone S, et al. Verification of the fetal valproate syndrome phenotype [review]. Am J Med Genet 1988;29(1):171-85.
19. Jager-Roman E., Deichl A, Jakob S, Hartmann AM, Koch S, Rating D, et al. Fetal growth, major malformations, and minor anomalies in infants born to women receiving valproic acid. J Pediatr 1986;108(6):997-1004.
20. Huot C, Gauthier M, Lebel M, Larbrisseau A. Congenital malformations associated with maternal use of valproic acid [review]. Can J Neurol Sci 1987;14(3):290-3.
21. Verloes A, Frikiche A, Gremillet C, Paquay T, Decortis T, Rigo J, et al. Proximal phocomelia and radial ray aplasia in fetal valproic syndrome. Eur Pediatr 1990;149(4):266-7.
22. Okada T, Tomoda T, Hisakawa H, Kurashige T. Fetal valproate syndrome with reduction deformity of limb. Acta Paediatr Jpn 1995;37(1):58-60.
23. Paulson RB, Sucheston ME, Hayes TG, Paulson GW. Teratogenic effects of valproate in the CD-1 mouse fetus. Arch Neurol 1985;42(10):980-3.
24. Petrere JA, Anderson JA, Sakowski R, Fitzgerald JE, de la Iglesia FA. Teratogenesis of calcium valproate in rabbits. Teratology 1986;34:263-9.
25. Sharony R, Garber A, Viskochil D, Schreck R, Platt LD, Ward R, et al. Preaxial ray reduction defects as part of valproic acid embryofetopathy. Prenat Diagn 1993;13(10):909-18.
26. Buntinx IM. Preaxial polydactyly in the fetal valproate syndrome [letter]. Eur J Pediatr 1992;151(12):919-20.
27. Clayton-Smith J, Donnai D. Fetal valproate syndrome. J Med Genet 1995;32(9):724-7.
28. Chitayat D, Farrell K, Anderson L, Hall JG. Congenital abnormalities in two sibs exposed to valproic acid in utero. Am J Med Genet 1988;31(2):369-73.
29. Christianson AL, Chesler N, Kromberg JG. Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs. Dev Med Child Neurol 1994;36(4):361-9.
30. DiLiberti JH, Farndon PA, Dennis NR, Curry CJ. The fetal valproate syndrome. Am J Med Genet 1984;19(3):473-81.
31. Clay SA, McVie R, Chen H. Possible teratogenic effect of valproic acid [letter]. J Pediatr 1981;99(5):828.
32. Thomas D, Buchanan N. Teratogenic effects of anticonvulsants. J Pediatr 1981;99:163.
33. Jones KL. Pattern of malformation in the children of women treated with carbamazepine during pregnancy. N Engl J Med 1989;320:1661.
34. Ardinger HH, Clark HB, Hanson JW. Cardiac malformations associated with fetal valproic acid exposure. Proc Greenwood Genet Center 1986;5:162.
35. Martinez-Frias ML. Clinical manifestation of prenatal exposure to valproic acid using case reports and epidemiologic information. Am J Med Genet 1990;37(2):277-82.
36. Boussemart T, Bonneau D, Levard G, Berthier M, Oriot D. Omphalocele in a newborn baby exposed to sodium valproate in utero. Eur J Pediatr 1995;154(3):220-1.
37. Thisted E, Ebbesen F. Malformations, withdrawal manifestations, and hypoglycaemia after exposure to valproate in utero. Arch Dis Child 1993;69(3 Spec No):288-91.
38. Brock DGH, Sutcliffe RG. Alphafetoprotein in the antenatal diagnosis of anencephaly and spina bifida. Lancet 1972;2:197-9.
39. Wladimiroff IW, Stewart PA, Reuss A, van Swaay E, Lindhout D, Sachs ES. The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy. Ultrasound Med Biol 1988;14(8):657-60.
40. Weinbaum PI, Cassidy SB, Vintzileos AM, Campbell WA, Ciarleglio L, Nochimson DJ. Prenatal detection of a neural tube defect after fetal exposure to valproic acid. Obstet Gynecol 1986;67(3 Suppl):31S-33S.
41. Guibaud S, Simplot A, Boisson C, Pison H. Prenatal diagnosis of 4 cases of spina bifida in mothers treated with valproate [French]. J Genet Hum 1987;35(4):231-5.
42. Brock DJH, Barron L, van Heyningen V. Prenatal diagnosis of neural tube defects with a monoclonal antibody specific for acetylcholinesterase. Lancet 1985;2:5-8.
43. Keen CL, Hurley LS. Zinc and reproduction: effects of deficiency on fetal and postnatal development. In: Mills CF, editor. Zinc in human biology. New York: Springer-Verlag; 1989.
44. Hansen DK, Grafton TF, Dial SL, Gehring TA, Siitonen PH. Effect of supplemental folic acid on valproic acid-induced embryotoxicity and tissue zinc levels in vivo. Teratology 1995;2:277-85.
45. Rice J, Reich T, Andreasen NC, Endicott J, Van Eerdewegh M, Fishman R, et al. The familial transmission of bipolar illness. Arch Gen Psychiatry 1987;44:441-7.
46. Dunner DL. Recent genetic studies of bipolar and unipolar depression. In: Davis JM, Maas JW, editors. The affective disorders. Washington (DC): American Psychiatric Press; 1983.
47. Packer S. Family planning for women with bipolar disorder. Hosp Community Psychiatry 1992;43(5):479-81.
48. Roza F. Spina bifida in infants of women treated with carbamazepine during pregnancy. N Engl J Med 1991;324:674-6.
49. Jacobson SJ, Jones K, Johnson K, Ceolin L, Kaur P, Sahn D, et al. Prospective, multicentre study of pregnancy outcome after lithium exposure during first trimester. Lancet 1992;339:530-3.