Transcriptional regulation of lysosomal acid lipase in differentiating monocytes is mediated by transcription factors Sp1 and AP-2

Journal of Lipid Research

Volumn 39, Issue 11, 1998, Pages 2125-2134

  Ries, Stefan ^a   Büchler, Christa ^a   Langmann, Thomas ^a   Fehringer, Petra ^a   Aslanidis, Charalampos ^a   Schmitz, Gerd ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Acid lipase; Cholesterol metabolism; Cholesteryl ester storage disease; Differentiation; Gene regulation; LAL promoter; Lysosome; Macrophage; Transcription factors; Wolman disease

Indexed keywords

ACID LIPASE; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; LIPOPROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR SP1; TRIACYLGLYCEROL;

ARTICLE; CELL DIFFERENTIATION; CHOLESTEROL ESTER STORAGE DISEASE; CHOLESTEROL METABOLISM; DNA FLANKING REGION; ENDOCYTOSIS; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYSOSOME; MONOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN RNA BINDING; PROTEIN SYNTHESIS; REPORTER GENE; TRANSCRIPTION REGULATION;

CELL DIFFERENTIATION; CELL LINE; CHOLESTEROL ESTERASE; CHROMOSOME MAPPING; DNA-BINDING PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MACROPHAGES; MONOCYTES; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 0031724011     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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