Up-regulation of the neuronal form of nitric oxide synthase in response to prolonged muscarinic M1 receptor stimulation

Journal of Neurochemistry

Volumn 71, Issue 2, 1998, Pages 571-579

  Cuadra, Adolfo E ^a   El Fakahany, Esam E ^a,b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

Chinese hamster ovary cells; Increased expression; Muscarinic acetylcholine receptors; N1E 115 neuroblastoma cells; Neuronal nitric oxide synthase; Nitric oxide synthase

Indexed keywords

CALCIUM; CARBACHOL; CITRULLINE; CYCLIC GMP; INOSITOL PHOSPHATE; MUSCARINIC M1 RECEPTOR; NITRIC OXIDE SYNTHASE; SCOPOLAMINE;

ANIMAL CELL; ARTICLE; BINDING COMPETITION; CHO CELL; CONCENTRATION RESPONSE; ENZYME REGULATION; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR UPREGULATION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0031723622     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71020571.x     Document Type: Article

References (47)

1. Arnold W. P., Mittal C. K., Katsuki S., and Murad F. (1977) Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations. Proc. Natl. Acad. Sci. USA 74, 3203-3207.
2. Ashkenazi A., Peralta E. G., Winslow J. W., Ramachandran J., and Capon D. J. (1989a) Functional diversity of muscarinic receptor subtypes in cellular signal transduction and growth. Trends Pharmacol. Sci. (Suppl.) 16-22.
3. Ashkenazi A., Peralta E. G., Winslow J. W., Ramachandran J., and Capon D. J. (1989b) Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell. Cell 56, 487-493.
4. Ashkenazi A., Ramachandran J., and Capon D. J. (1989c) Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes. Nature 340, 146-150.
5. Bagetta G., Corasaniti M. T., Melino G., Paoletti A. M., Finazzi-Agro A., and Nistico G. (1993a) Lithium and tacrine increase the expression of nitric oxide synthase mRNA in the hippocampus of rat. Biochem. Biophys. Res. Commun. 197, 1132-1139.
6. Bagetta G., Massoud R., Rodino P., Federici G., and Nistico G. (1993b) Systemic administration of lithium chloride and tacrine increases nitric oxide synthase activity in the hippocampus of rats. Eur. J. Pharmacol. 237, 61-64.
7. Berridge M. J. and Irvine R. F. (1989) Inositol phosphates and cell signalling. Nature 341, 197-204.
8. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
9. Bredt D.S. and Snyder S. H. (1994) Nitric oxide: a physiologic messenger molecule. Annu. Rev. Biochem. 63, 175-195.
10. Caulfield M. P. (1993) Muscarinic receptors - characterization, coupling and function. Pharmacol Ther. 58, 319-379.
11. Crow J. P. and Beckman J. S. (1995) Reactions between nitric oxide, Superoxide, and peroxynitrite: footprints of peroxynitrite in vivo, in Nitric Oxide: Biochemistry, Molecular Biology, and Therapeutic Implications (Ignarro L. and Murad F., eds), pp. 17-43. Academic Press, San Diego.
12. Cuadra A. E. and El-Fakahany E. E. (1997) Enhancement of maximal activation of neuronal nitric oxide synthase at muscarinic M1 receptors following prolonged agonist treatment. Eur. J. Pharmacol. 334, 107-110.
13. Dawson D. A. (1994) Nitric oxide and focal cerebral ischemia: multiplicity of actions and diverse outcome. Cereb. Brain Metab. Rev. 6, 299-324.
14. Dawson T. M. and Snyder S. H. (1994) Gases as biological messengers: nitric oxide and carbon monoxide in the brain. J. Neurosci. 14, 5147-5159.
15. El-Fakahany E. E. and Cioffi C. L. (1990) Molecular mechanisms of regulation of neuronal muscarinic receptor sensitivity. Membr. Biochem. 9, 9-27.
16. Elmer E., Alm P., Kokaia Z., Kokaia M., Larsson B., Keep M., Andersson K. E., and Lindvall O. (1996) Regulation of neuronal nitric oxide synthase mRNA levels in rat brain by seizure activity. Neuroreport 7, 1335-1339.
17. Feigenbaum P. and El-Fakahany E. E. (1985) Regulation of muscarinic cholinergic receptor density in neuroblastoma cells by brief exposure to agonist: possible involvement in desensitization of receptor function. J. Pharmacol. Exp. Ther. 233, 134-140.
18. Garthwaite J. and Boulton C. L. (1995) Nitric oxide signaling in the central nervous system. Annu. Rev. Physiol. 57, 683-706.
19. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
20. Gutkind J. S., Novotny E. A., Brann M. R., and Robbins K. C. (1991) Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes. Proc. Natl. Acad. Sci. USA 88, 4703-4707.
21. Haley J. E., Schaible E., Pavlidis P., Murdock A., and Madison D. V. (1996) Basal and apical synapses of CA1 pyramidal cells employ different LTP induction mechanisms. Learn. Mem. 3, 289-295.
22. Hu J., Wang S. Z., and El-Fakahany E. E. (1991) Effects of agonist efficacy on desensitization of phosphoinositide hydrolysis mediated by m1 and m3 muscarinic receptors expressed in Chinese hamster ovary cells. J. Pharmacol. Exp. Ther. 257, 938-945.
23. Ignarro L. J. (1992) Mechanism of action of nitric oxide: hemedependent activation of guanylate cyclase represents a unifying signal transduction mechanism. Jpn. J. Pharmacol. 58, 207P-212P.
24. Levey A. I. (1997) Muscarinic acetylcholine receptor expression in memory circuits: implications for treatment of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 93, 13541-13546.
25. 2+ influx. J. Neurosci. 16, 1702-1709.
26. McKinney M. and Coyle J. T. (1991) The potential for muscarinic receptor subtype-specific pharmacotherapy for Alzheimer's disease. Mayo Clin. Proc. 66, 1225-1237.
27. 1 muscarinic acetylcholine receptor expressed in CHO cells. Biochem. J. 293, 495-499.
28. Mullaney I., Dodd M. W., Buckley N., and Milligan G. (1993a) Agonist activation of transfected human M, muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the alpha subunit. Blochem. J. 289, 125-131.
29. 11 alpha equally and non-selectively. FEBS Lett. 324, 241-245.
30. Nathan C. and Xie Q. W. (1994) Nitric oxide synthases: roles, tolls, and controls. Cell 78, 915-918.
31. Ogilvie P., Schilling K., Billingsley M. L., and Schmidt H. H. H. W. (1995) Induction and variants of neuronal nitric oxide synthase type I during synaptogenesis. FASEB J. 9, 799-806.
32. Peunova N. and Enikolopov G. (1993) Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells. Nature 364, 450-453.
33. 2+ mobilization from stores expressing inositol 1,4,5-trisphosphate receptors and ryanodine receptors in cerebellar granule neurones. J. Neurochem. 67, 364-373.
34. Smrcka A. V., Hepler J. R., Brown K. O., and Sternweis P. C. (1991) Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. Science 251, 804-807.
35. Son H., Hawkins R. D., Martin K., Kiebler M., Huang P. L., Fishman M. C., and Kandel E. R. (1996) Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase. Cell 87, 1015-1023.
36. Stephens E. V., Kalinec G., Brann M. R., and Gutkind J. S. (1993) Transforming G protein-coupled receptors transduce potent mitogenic signals in NIH 3T3 cells independent on cAMP inhibition or conventional protein kinase C. Oncogene 8, 19-26.
37. 2+ mobilization in muscarinic and histamine receptor-mediated activation of guanylate cyclase in N1E-115 neuroblastoma cells: assessment of the arachidonic acid release hypothesis. Mol. Pharmacol. 37, 860-869.
38. Tohda M., Tohda C., Sakuma S., Higashida H., and Nomura Y. (1994) Distinct induction of c-fos mRNA in NG108-15 cells transfected with muscarinic m1 and m3 receptors. Eur. J. Pharmacol. 168, 169-176.
39. Wang S.Z., Hu J. R., Long R. M., Pou W. S., Forray C., and El-Fakahany E. E. (1990) Agonist-induced down-regulation of m1 muscarinic receptors and reduction of their mRNA level in a transfected cell line. FEBS Lett. 276, 185-188.
40. Wang S. Z., Zhu S. Z., and El-Fakahany E. E. (1994) Efficient coupling of m5 muscarinic acetylcholine receptors to activation of nitric oxide synthase. J. Pharmacol. Exp. Ther. 268, 552-557.
41. Weiner C. P., Knowles R. G., and Moncada S. (1994a) Induction of nitric oxide synthases early in pregnancy. Am. J. Obstet. Gynecol. 171, 838-843.
42. Weiner C. P., Lizasoain I., Baylis S. A., Knowles R. G., Charles I. G., and Moncada S. (1994b) Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc. Natl. Acad. Sci. USA 91, 5212-5216.
43. 2+ and by rapid desensitization. J. Neurochem. 63, 177-185.
44. Wotta D. R. and El-Fakahany E. E. (1997) Muscarinic receptor-mediated activation of nitric oxide sythase. Drug Dev. Res. 40, 205-214.
45. Wu Y., Li Y., Liu H., and Wu W. (1995) Induction of nitric oxide synthase and motoneuron death in newborn and early postnatal rats following spinal root avulsion. Neurosci. Lett. 194, 109-112.
46. Yu W. H. (1994) Nitric oxide synthase in motor neurons after axotomy. J. Histochem. Cytochem. 42, 451-457.
47. Zhang Z. G., Chopp M., Gautam S., Zaloga C., Zhang R. L., Schmidt H. H., Pollock J. S., and Forstermann U. (1994) Upregulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after focal cerebral ischemia in rat. Brain Res. 654, 85-95.