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Fisher SE, Vargha-Khadem F, Watkins KE, Monaco AP, Pembrey ME: Localisation of a gene implicated in a severe speech and language disorder. Nat Genet 1998, 18:168-170. This exciting study suggests linkage to a particular chromosome of a well-defined subtype of language disorder in the very large family described by Vargha-Khadem et al. (Proc Nat Acad Sci USA 1995, 92:930-933) that has already been the subject of a series of publications. Although DLD is presumed to be genetically heterogeneous and possibly polygenic, this family suggests that in some cases single gene defects may be responsible for DLD. If such a gene is isolated rt may enlighten us about the pathophysiology of such a complex ability as language.
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Rapin I, Dunn M: Language disorders in children with autism. Semin Pediatr Neurol 1997, 4:86-92. This review provides more detailed information on the many aspects of language and communication in individuals in the autistic spectrum than was possible in the current review.
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