Pathophysiology and diagnosis in patients with sympathatically dependent pain;Pathophysiologie und diagnostik von sensiblen storungen bei sympathikus- abhangigen schmerzen

Schmerz

Volumn 12, Issue 4, 1998, Pages 250-260

  Treede, R D ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Adrenoreceptors; Allodynia; Clonidine; Guanethidine; Local anaesthetics; Neuropathic pain; Norepinephrine; Phentolamine; Regional pain; Secondary hyperalgesia; Sympathetically maintained pain

Indexed keywords

ADRENERGIC TRANSMISSION; CHRONIC PAIN; HUMAN; HYPERALGESIA; NOCICEPTION; PATHOPHYSIOLOGY; REVIEW; SYMPATHETIC DYSTROPHY; SYMPATHETIC TONE; ARTICLE;

EID: 0031723215     PISSN: 0932433X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004820050150     Document Type: Review

References (65)

1. Abram SE, Lightfoot RW (1981) Treatment of long-standing causalgia with prazosin. Reg Anest 6:79
2. Arnér S (1991) Intravenous phentolamine test: diagnostic and prognostic use in reflex sympathetic dystrophy. Pain 46:17
3. Arnold JMO, Teasell RW, MacLeod AP, Brown JE, Carruthers SG (1993) Increased venous alpha-adrenoceptor responsiveness in patients with reflex sympathetic dystrophy. Ann Intern Med 118:619
4. Backonja M, Arndt G, Gombar KA, Check B, Zimmermann M (1994) Response of chronic neuropathic pain syndromes to ketamine - a preliminary study. Pain 56:51
5. Blumberg H (1988) Zur Entstehung und Therapie des Schmerzsyndroms bei der sympathischen Reflexdystrophie. Schmerz 2:125
6. Blumberg H (1993) Sympathische Reflexdystrophie. In:Zenz M,Jurna I (Hrsg) Lehrbuch der Schmerztherapie: Grundlagen,Theorie und Praxis für Aus- und Weiterbildung. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 369
7. Boivie J, Leijon G (1991) Clinical findings in patients with central poststroke pain. In:Casey KL (ed) Pain and central nervous system disease: the central pain syndromes. Raven Press, New York, p 65
8. Bonica JJ (1979) Causalgia and other reflex sympathetic dystrophies. In: Bonica JJ (ed) Advances in pain research and therapy, vol 3. Raven Press, New York, p 141
9. Bossut DF, Shea VK, Perl ER (1996) Sympathectomy induces adrenergic excitability of cutaneous C-fiber nociceptors. J Neurophysiol 75:514
10. Campbell JN, Raja SN, Meyer RA, Mackinnon SE (1988) Myelinated afferents signal the hyperalgesia associated with nerve injury. Pain 32:89
11. Campbell JN, Meyer RA, Davis KD, Raja SN (1992) Sympathetically maintained pain. A unifying hypothesis. In: Willis WD (ed) Hyperalgesia and allodynia. Raven Press, New York, p141
12. Cervero F, Laird JMA (1991) One pain or many pains? A new look at pain mechanisms. News Physiol Sci 6:268
13. Davis KD, Treede R-D, Raja SN, Meyer RA, Campbell JN (1991) Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain. Pain 47:309
14. Dellemijn PLI, Fields HL, Allen RR, Mckay WR, Rowbotham MC (1994) The interpretation of pain relief and sensory changes following sympathetic blockade. Brain 117:1475
15. Doupe J, Cullen CH, Chance GQ (1944) Post-traumatic pain and the causalgic syndrome. J Neurol Neurosurg Psychiatry 7:33
16. Drummond PD, Finch PM, Smythe GA (1991) Reflex sympathetic dystrophy: the significance of differing plasma catecholamine concentrations in affected and unaffected limbs. Brain 114:2025
17. 1-adrenoceptors in normal and hyperalgesic human skin. Clin Sci 91:73
18. Eide PK, Jorum E, Stubhaug A, Bremnes J, Breivik H (1994) Relief of post-herpetic neuralgia with the N-methyl-D- aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo. Pain 58:347
19. Eisenberg E,Pud D (1998) Can patients with chronic neuropathic pain be cured by acute adminstration of the NMDA receptor antagonist amantadine? Pain 74:337
20. Fagius J, Wallin BG (1983) Microneurographic evidence of excessive sympathetic outflow in the Guillain-Barré syndrome. Brain 106:589
21. Frost SA, Raja SN, Campbell JN, Meyer RA, Khan AA (1988) Does hyperalgesia to cooling stimuli characterize patients with sympathetically maintained pain (reflex sympathetic dystrophy)? In: Dubner R, Gebhart GF, Bond MR (eds) Proceedings of the Vth World Congress on Pain. Elsevier, Amsterdam New York, p 151
22. Ghostine SY,Comair YG, Turner DM, Kassell NF, Azar CG (1984) Phenoxybenzamine in the treatment of causalgia. Report of 40 cases. J Neurosurg 60:1263
23. Glynn CJ, Basedow RW,Walsh JA (1981) Pain relief following post-ganglionic sympathetic blockade with i.V. guanethidine. Br J Anaesth 53:1297
24. Gracely RH, Lynch SA, Bennett GJ (1992) Painful neuropathy: altered central processing, maintained dynamically by peripheral input. Pain 51:175
25. Jänig W (1992) Is the reflex sympathetic dystrophy a neurological disease? In Jänig W, Schmidt RF (eds) Reflex sympathetic dystrophy. Verlag Chemie, Weinheim, p9
26. Jänig W, Koltzenburg M (1992) Possible ways of sympathetic-afferent interactions. In:Jänig W, Schmidt RF (eds) Reflex sympathetic dystrophy. Verlag Chemie, Weinheim, p213
27. Koltzenburg M, Torebjörk HE,Wahren LK (1994) Nociceptor modulated central sensitization causes mechanical hyperalgesia in acute chemogenic and chronic neuropathic pain. Brain 117:579
28. Kurvers HAJM, Jacobs MJHM, Beuk RJ, Wildenberg FAJM van den, Kitslaar PJEHM, Slaaf DW, Reneman RS (1994) Reflex sympathetic dystrophy: result of autonomic denervation? Clin Sci 87:663
29. Kurvers HAJM, Jacobs MJHM, Beuk RJ, Wildenberg FAJM van den, Kitslaar PJEHM, Slaaf DW, Reneman RS (1996) The spinal component to skin blood flow abnormalities in reflex sympathetic dystrophy. Arch Neurol 53:58
30. LaMotte RH, Shain CN, Simone DA, Tsai E-FP (1991) Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms. J Neurophysiol 66:190
31. Lindblom U, Verrillo RT (1979) Sensory functions in chronic neuralgia. J Neurol Neurosurg Psychiatry 42:422
32. Loh L, Nathan PW (1978) Painful peripheral states and sympathetic blocks. J Neurol Neurosurg Psychiatry 41:664
33. Magerl W, Wilk SH, Treede R-D (1998) Secondary hyperalgesia and perceptual wind-up following intradermal injection of capsaicin in humans. Pain 74:257
34. Maier C (1995) Was ist der "sympathisch unterhaltene Schmerz" oder wie "Pu der Bär" den Nordpol entdeckte. Schmerz 9:269
35. Max MB, Byas-Smith MG, Gracely RH, Bennett GJ (1995) Intravenous infusion of the NMDA antagonist, ketamine, in chronic posttraumatic pain with allodynia: a double-blind comparison to alfentanil and placebo. Clin Neuropharmacol 18:360
36. McMahon SB, Lewin GR,Wall PD (1993) Central hyperexcitability triggered by noxious inputs. Curr Opin Neurobiol 3:602
37. Meyer RA, Treede R-D, Raja SN, Campbell JN (1992) Peripheral versus central mechanisms for secondary hyperalgesia. Is the controversy resolved? APS Journal 1:127
38. Nikolajsen L, Hansen CL, Nielsen J, Keller J, Arendt-Nielsen L, Jensen TS (1996) The effect of ketamine on phantom pain:a central neuropathic disorder maintained by peripheral input. Pain 67:69
39. Price DD, Bennett GJ, Rafii A (1989) Psychophysical observations on patients with neuropathic pain relieved by a sympathetic block. Pain 36:273
40. Raja SN (1993) Diagnosis of sympathetically maintained pain: the past, present and future. Eur J Pain 14:45
41. Raja SN, Campbell JN, Meyer RA (1984) Evidence for different mechanisms of primary and secondary hyperalgesia following heat injury to the glabrous skin. Brain 107:1179
42. Raja SN, Treede R-D, Davis KD, Campbell JN (1991) Systemic alpha-adrenergic blockade with phentolamine: a diagnostic test for sympathetically maintained pain. Anesthesiology 74:691
43. Raja SN, Jurnquist JL, Meleka S, Campbell JN (1996) Monitoring adequacy of alphaadrenoceptor blockade following systemic phentolamine administration. Pain 64:197
44. Ramamurthy S, Hoffman J, Abadir A, Baysinger C, Edwards BE, Edwards WT, Hare BD, Ingall JR, Mangieri EA, Mogelnicki SR, Racz GA, Raj P,Rauck RL, Rosenblum S, Strickland J, Yalamanchili P (1995) Intravenous regional guanethidine in the treatment of reflex sympathetic dystrophy/causalgia: a randomized, double-blind study. Anesth Analg 81:718
45. Roberts WJ (1986) A hypothesis on the physiological basis for causalgia and related pains. Pain 24:297
46. Rowbotham MC, Reisner-Keller LA, Fields HL (1991) Both intravenous lidocaine and morphine reduce the pain of postherpetic neuralgia. Neurology 41:1024
47. Sato A, Schmidt RF (1973) Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics. Physiol Rev 53:916
48. Schimek F, Benda N, Töpfner S (1995) Der "Guanethidin-Test" ist ein wertloser diagnostischer Test. Schmerz 9:S63
49. Shir Y, Cameron LB, Raja SN, Bourke DL (1991) The safety of intravenous phentolamine administration in patients with neuropathic pain. Anesth Analg 76:1008
50. Simone DA, Sorkin LS, Oh U, Chung JM, Owens C, LaMotte RH, Willis WD (1991) Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons. J Neurophysiol 66:228
51. Stanton-Hicks M, Jänig W, Hassenbusch S, Haddox JD, Boas R, Wilson P (1995) Reflex sympathetic dystrophy: changing concepts and taxonomy. Pain 63:127
52. Steen KH, Reeh PW, Anton F, Handwerker HO (1992) Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro. J Neurosci 2:86
53. Thompson SWN, Woolf CJ, Sivilotti LG (1993) Small-caliber afferent inputs produce a heterosynaptic facilitation of the synaptic responses evoked by primary afferent A-fibers in the neonatal rat spinal cord in vitro. J Neurophysiol 69:2116
54. Torebjörk HE, Lundberg LER, LaMotte RH (1992) Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia. J Physiol 448:765
55. Torebjörk E, Wahren LK, Wallin G, Hallin R, Koltzenburg M (1995) Noradrenalineevoked pain in neuralgia. Pain 63:11
56. Treede R-D, Magerl W (1995) Modern concepts of pain and hyperalgesia: beyond the polymodal C-nociceptor. News Physiol Sci 10:216
57. Treede R-D, Raja SN, Davis KD, Meyer RA, Campbell JN (1991) Evidence that peripheral alpha-adrenergic receptors mediate sympathetically maintained pain. In:Bond MR, Charlton JE, Woolf CJ (eds) Proceedings of the Vth World Congress on Pain. Elsevier, Amsterdam New York, p 377
58. Treede R-D, Davis KD, Campbell JN, Raja SN (1992) The plasticity of cutaneous hyperalgesia during sympathetic ganglion blockade in patients with neuropathic pain. Brain 115:607
59. Treede R-D, Meyer RA, Raja SN,Campbell JN (1992) Peripheral and central mechanisms of cutaneous hyperalgesia. Prog Neurobiol 38:397
60. Verdugo RJ, Ochoa JL (1994) 'Sympathetically maintained pain'. 1. Phentolamine block questions the concept. Neurology 44:1003
61. Wahren LK, Torebjörk E, Nyström B (1991) Quantitative sensory testing before and after regional guanethidine block in patients with neuralgia in the hand. Pain 46:23
62. Walker E, Nulson F (1948) Electrical stimulation of the upper thoracic portion of the sympathetic chain in man. Arch Neurol Psychiatry (Chicago) 59:559
63. Wallin G, Torebjörk E, Hallin R (1976) Preliminary observations on the pathophysiology of hyperalgesia in the causalgic pain syndrome. In:Zotterman Y (ed) Sensory functions of the skin in primates. Pergamon Press, Oxford New York, p489
64. Woolf CJ, Doubell TP (1994) The pathophysiology of chronic pain - increased sensitivity to low threshold A-beta-fibre inputs. Curr Opin Neurobiol 4:525
65. Zenz M, Jurna I (1993) Lehrbuch der Schmerztherapie: Grundlagen, Theorie und Praxis für Aus- und Weiterbildung. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart