The roles of depot injection sites and proximal lymph nodes in the presystemic absorption of fluphenazine decanoate and fluphenazine: Ex vivo experiments in rats
ANIMAL EXPERIMENT;
ANIMAL TISSUE;
ARTICLE;
DRUG ABSORPTION;
DRUG BLOOD LEVEL;
DRUG DELIVERY SYSTEM;
DRUG HALF LIFE;
DRUG RELEASE;
DRUG TISSUE LEVEL;
FEMALE;
HYDROLYSIS;
INJECTION SITE;
INTRAMUSCULAR DRUG ADMINISTRATION;
LYMPH NODE;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
Sensitive method for the simultaneous measurement of fluphenazine decanoate and fluphenazine in plasma by high-performance liquid chromatography with coulometric detection
J.-P. Luo, J. W. Hubbard, and K. K. Midha. Sensitive method for the simultaneous measurement of fluphenazine decanoate and fluphenazine in plasma by high-performance liquid chromatography with coulometric detection. J. Chromatogr. Biomed. Applic. 688:303-308 (1997).
Studies on the mechanism of absorption of depot neuroleptics:. fluphenazine decanoate in sesame oil
J.-P. Luo, J. W. Hubbard, and K. K. Midha. Studies on the mechanism of absorption of depot neuroleptics:. fluphenazine decanoate in sesame oil. Pharm. Res. 14:1079-1084 (1997).
Fluphenazine enanthate and fluphenazine decanoate: Intramuscular injection and esterification as requirement for slow-release characteristics in dogs
J. Drefuss, J. Shaw, and J. Ross. Fluphenazine enanthate and fluphenazine decanoate: intramuscular injection and esterification as requirement for slow-release characteristics in dogs. J. of Pharm. Sci. 65:1310-1315 (1976).
Studies on the fate of vegetable oil after intramuscular injection into experimental animals
O. Sevendsen and T. Aaes-Jorgensen. Studies on the fate of vegetable oil after intramuscular injection into experimental animals. Acta Pharm. Toxicol. 45:352-378 (1979).
Absorption of intramuscularly administered [14C]-haloperidol in rats
Y. Matsunaga, K. Nambu, Y. Oh-e, H. Miyazaki, and M. Hashimoto. Absorption of intramuscularly administered [14C]-haloperidol in rats. Eur. J. Drug Metab. Pharmacokin. 12:175-181 (1987).
The role of the lymphatic system in the presystemic absorption of fluphenazine after intramuscular administration of fluphenazine decanoate in rats
Y. Huang, J. W. Hubhard, and K. K. Midha. The role of the lymphatic system in the presystemic absorption of fluphenazine after intramuscular administration of fluphenazine decanoate in rats. Eur. J. Pharm. Sci. 3:15-20 (1995).
Metabolism, distribution and excretion of flupenthixol decanoate in dogs and rats
T. Aaes-Jorgesen, K. Overo, and V. Hansen. Metabolism, distribution and excretion of flupenthixol decanoate in dogs and rats. Acta Pharmacol. Toxicol. 29:339-358 (1972).