Cardiorespiratory, tissue oxygen and hepatic NADH responses to graded hypoxia

Intensive Care Medicine

Volumn 24, Issue 11, 1998, Pages 1209-1216

  Stidwill, R P ^a   Rosser, D M ^a   Singer, M ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Haemodynamics; Hypoxaemia; Hypoxic hypoxia; NADH; Tissue oxygen

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ANIMAL MODEL; AORTA FLOW; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; FLUORESCENCE; HYPOXEMIA; HYPOXIA; KIDNEY BLOOD FLOW; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXYGEN CONCENTRATION; OXYGEN TISSUE LEVEL; PROSPECTIVE STUDY; RAT;

ANIMALS; ANOXIA; BLOOD GAS ANALYSIS; CELL HYPOXIA; DISEASE MODELS, ANIMAL; HEMODYNAMIC PROCESSES; LIVER; MALE; NAD; OXYGEN CONSUMPTION; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SURVIVAL ANALYSIS;

EID: 0031722149     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340050746     Document Type: Article

References (23)

1. Chance B, Graham N, Mayer D (1971) A time sharing fluorometer for the readout of intracellular oxidation-reduction states of NADH and flavoprotein. Rev Sci Instrum 42: 951-957
2. Ince C, Ashruf JF, Sanderse EA, Pierik EG, Coremans JM, Bruining HA (1992) In vivo NADH and Pd-porphyrin video fluori-/phosphorimetry. Adv Exp Med Biol 317: 267-275
3. Ince C, Coremans JM, Bruining HA (1992) In vivo NADH fluorescence. Adv Exp Med Biol 317: 277-296
4. Thorniley MS, Simpkin S, Fuller B, Jenabzadeh MZ, Green CJ (1995) Monitoring of surface mitochondrial NADH levels as an indication of ischemia during liver isograft transplantation. Hepatology 21: 1602-1609
5. Singer M, Millar C, Stidwill RP, Unwin R (1995) Bladder epithelial oxygen tension - a new means of monitoring regional perfusion? Preliminary study in a model of exsanguination/fluid repletion. Intensive Care Med 22: 324-328
6. Rosser DM, Stidwill R P, Millar CG, Singer M (1995) The effect of norepinephrine and dobutamine on bladder epithelial oxygen tension. Chest 108: 1368-1372
7. Rosser DM, Stidwill RP, Jacobson DJ, Singer M (1996) Cardio-respiratory and tissue dose response to rat endotoxemia. Am J Physiol 271:H891-H895
8. Duckrow RB, LaManna JS, Rosenthal M (1981) Disparate recovery of resting and stimulated oxidative metabolism following transient ischemia. Stroke 12: 677-686
9. Obi-Tabot TE, Hanrahan LM, Cachecho R, Beer ER, Hopkins SR, Chan JC, Shapiro JM, LaMorte WW (1993) Changes in hepatocyte NADH fluorescence during prolonged hypoxia. J Surg Res 55: 575-580
10. Yager JY, Brucklacher RM, Vannucci RC (1991) Cerebral oxidative metabolism and redox state during hypoxia-ischemia and early recovery in immature rats. Am J Physiol 261: H1102-H1108
11. Walker BR, Brizzee BL (1988) Renal vascular response to combined hypoxia and hypercapnia in conscious rats. Am J Physiol 254: R552-R558
12. Zillig B, Schuler G, Truniger B (1978) Renal function and intrarenal hemodynamics in acutely hypoxic and hypercapnic rats. Kidney Int 14: 58-67
13. Durieux ME, Sperry RJ, Longnecker DE (1992) Effects of hypoxemia in regional blood flows during anesthesia with halothane, enflurane or isoflurane. Anesthesiology 76: 402-408
14. Sugai M (1996) Comparison of the effect of isoflurane and that of sevoflurane on hepatic circulation and oxygen metabolism during acute hypoxia in dogs. Masui 45: 608-616
15. Hoka S, Bosnjak ZJ, Arimura H, Kampine JP (1989) Regional venous outflow, blood volume and sympathetic nerve activity during severe hypoxia. Am J Physiol 256: H162-H170
16. Krasney JA, Hajduczok G, Miki K, Matalon S (1985) Peripheral circulatory responses to 96 hours of eucapnic hypoxia in conscious sheep. Respir Physiol 59: 197-211
17. Larsen JA, Krarup N, Munck A (1976) Liver hemodynamics and liver function in cats during graded hypoxic hypoxemia. Acta Physiol Scand 98: 257-262
18. Boekstegers P, Weidenhofer S, Pilz G, Werdan K (1991) Peripheral oxygen availability within skeletal muscle in sepsis and septic shock: comparison to limited infection and cardiogenic shock. Infection 19: 317-323
19. Nordin A, Makisalo H, Hockerstedt K (1994) Dopamine infusion during resuscitation of experimental hemorrhagic shock. Crit Care Med 22: 151-156
20. Nuutinen EM, Wilson DF, Erecinska M (1984) Mitochondrial oxidative phosphorylation: tissue oxygen sensor for regulation of coronary flow. Adv Exp Med Biol 169: 351-357
21. Wilson DF, Mokashi A, Chugh D, Vinogradov S, Osanai S, Lahiri S (1994) The primary oxygen sensor of the cat carotid body is cytochrome a3 of the mitochondrial respiratory chain. FEBS Lett 351: 370-374
22. Duranteau J, Chandel NS, Kulisz A, Shao Z, Schumacker PT (1998) Intracellular signalling by reactive oxygen species during hypoxia in cardiomyocytes. J Biol Chem 273: 11619-11624
23. Harper SL, Pitts VH, Granger DN, Kvietys PR (1986) Pancreatic tissue oxygenation during secretory stimulation. Am J Physiol 250: G316-G322