Adrenal angiotensin II type 1 and type 2 receptors in Cushing's and Conn's syndromes

Molecular and Cellular Endocrinology

Volumn 144, Issue 1-2, 1998, Pages 37-45

  Kitamura, Yudai ^a   Sasamura, Hiroyuki ^a   Maruyama, Tatsuya ^a   Nakaya, Hideaki ^a   Amemiya, Tetsuro ^a   Hayashi, Matsuhiko ^a   Saruta, Takao ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Adenoma; Adrenal; Angiotensin II; Conn; Cushing; Receptors

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; MESSENGER RNA;

ADRENAL CORTEX ADENOMA; ADRENAL GLAND; ALTERNATIVE RNA SPLICING; ARTICLE; CARCINOGENESIS; CUSHING SYNDROME; GENE EXPRESSION; HUMAN; HUMAN TISSUE; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADRENAL CORTEX; ADRENAL CORTEX NEOPLASMS; ADRENOCORTICAL ADENOMA; ADULT; ALTERNATIVE SPLICING; CUSHING SYNDROME; FEMALE; HUMANS; HYPERALDOSTERONISM; MALE; MIDDLE AGED; PROTEIN ISOFORMS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0031721925     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(98)00159-2     Document Type: Article

References (17)

1. Brown G., Douglas J., Bravo E. Angiotensin II receptors and in vitro aldosterone responses of aldosterone-producing adenomas, adjacent nontumorous tissue, and normal human adrenal glomerulosa. J. Clin. Endocrinol. Metab. 51:1980;718-723.
2. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
3. Curnow K.M., Pascoe L., Davies E., White P.C., Corvol P., Clauser E. Alternatively spliced human type I angiotensin II receptor mRNAs are translated at different efficiencies and encode two receptor isoforms. Mol. Endocrinol. 9:1995;1250-1262.
4. Davies E., Bonnardeaux A., Plouin P., Corvol P., Clauser E. Somatic mutations of the angiotensin II (AT1) receptor gene are not present in aldosterone producing adenoma. J. Clin. Endocrinol. Metab. 82:1997;611-615.
5. Dzau V.J., Sasamura H., Hein L. Heterogeneity of angiotensin synthetic pathways and receptor subtypes: physiological and pharmacologic implications. J. Hypertens. 11(Suppl. 3):1993;S13-S18.
6. Hein L., Barsh G.S., Pratt R.E., Dzau V.J., Kobilka B.K. Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice. Nature. 377:1995;744-747.
7. Ichiki T., Labosky P.A., Shiota C., Okuyama S., Imagawa Y., Fogo A., Niimura F., Ichikawa I., Hogan B.L.M., Inagami T. Effects on blood pressure and exploratory behavior of mice lacking angiotensin II type-2 receptor. Nature. 377:1995;748-750.
8. Inagami T., Guo D.-F., Kitami Y. Molecular biology of angiotensin II receptors: an overview. J. Hypertens. 12(Suppl. 10):1994;S83-S94.
9. Klemm S.A., Ballantine D.M., Tunny T.J., Stowasser M., Gordon R.D. PCR-SSCP analysis of the angiotensin II type 1 receptor gene in patients with aldosterone-producing adenoma. Clin. Exp. Pharmacol. Physiol. 22:1995;457-459.
10. Liakos P., Bourmeyster N., Defaye G., Chambaz E.M., Bottari S.P. ANG II AT1 and AT2 receptors both inhibit bFGF-induced proliferation of bovine adrenocortical cells. Am. J. Physiol. 273:1997;C1324-C1334.
11. Lu X.Y., Grove K.L., Zhang W., Speth R.C. Pharmacological characterization of angiotensin II AT2 receptor subtype heterogeneity in the rat adrenal cortex and medulla. Endocr. J. 3:1995;255-261.
12. Mazzocchi G., Malendowicz L.K., Gottardo G., Rebuffat P., Nussdorfer G.G. Angiotensin II stimulates DNA synthesis in rat adrenal zone glomerulosa cells: receptor subtypes involved and possible signal transduction mechanisms. Endocr. Res. 23:1997;191-203.
13. Nawata H., Takayanagi R., Ohnaka K., Sakai Y., Imasaki K., Yanase T., Ikuyama S., Tanaka S., Ohe K. Type I angiotensin II receptors of adrenal tumors. Steroids. 60:1995;28-34.
14. Opocher G., Rocco S., Cimolato M., Vianello B., Arnaldi G., Mantero F. Angiotensin II receptors in cortical and medullary adrenal tumors. Endocrinology. 82:1997;865-869.
15. Sarzani R., Opocher G., Dessifulgheri P., Paci V., Cola G., Rocco S., Vianello B., Mantero F., Rappelli A. Expression of type I angiotensin II receptors in human aldosteronomas. Endocr. Res. 21:1995;189-195.
16. Timmermans P.B.M.W.M., Wong P.C., Chiu A.T., Herblin W.F. Nonpeptide angiotensin II receptor antagonists. Trends Pharmacol. Sci. 12:1991;55-62.
17. Yamada T., Horiuchi M., Dzau V.J. Angiotensin II type 2 receptor mediates programmed cell death. Proc. Natl. Acad. Sci. USA. 93:1996;156-160.