Serum levels of thyroxine-binding prealbumin, C-reactive protein and interleukin-6 in protein-energy undernourished children and normal controls without or with associated clinical infections

Journal of Tropical Pediatrics

Volumn 44, Issue 5, 1998, Pages 256-262

  Malavé, Inés ^a,b   Vethencourt, María Alejandra ^a   Pirela, Moravia ^a   Cordero, Raimundo ^a  

^a Instisuto Venez de Invest Cie   (Venezuela)

^b NONE   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERLEUKIN 6; PREALBUMIN; RABBIT ANTISERUM;

ARTICLE; BLOOD LEVEL; BODY HEIGHT; BODY WEIGHT; CALIBRATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION FUNCTION; HUMAN; IMMUNODIFFUSION; INFANT; INFECTION; MAJOR CLINICAL STUDY; MALNUTRITION; NUTRITIONAL STATUS; PRESCHOOL CHILD;

EID: 0031721446     PISSN: 01426338     EISSN: None     Source Type: Journal    
DOI: 10.1093/tropej/44.5.256     Document Type: Article

References (48)

1. Gordon JE, Scrimshaw, NS. Infectious disease in the malnourished. Med Clin North Am 1970; 54: 1495-508.
2. Chandra RK. Nutrition and immunoregulation. Significance for host resistance to tumors and infectious diseases in human and rodents. J Nutr 1992; 122 (Suppl. 3): 754-7.
3. Gershwin E, Beach RS, Hurley LS. Nutrition and Immunity. Academic Press, Orlando, 1985
4. Fleck A. Clinical and nutritional aspects of changes in acute-phase proteins during inflammation. Proc Nutr Soc 1989; 48: 347-54.
5. Steel DM, Whitehead AS. The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein. Immunol Today 1994; 13: 81-8.
6. Smith FR, Goodman DeWS, Zaklama MS, Gabr MK, El Maraghy S, Patwardhan VN. Serum vitamin A, retinol binding protein and prealbumin concentrations in protein-calorie malnutrition. I. A functional defect in hepatic retinol release. Am J Clin Nutr 1973; 26: 973-81.
7. Smith FR, Suskind R, Thanangkul O, Leitzmann C, Goodman DS, Olson RE. Plasma vitamm A, retinol-binding proteins and prealbumin concentrations in protein-calorie malnutrition III Response to varying dietary treatment. Am J Clin Nutr 1975; 28: 732-8.
8. Ingenbleek Y, Van Den Schrieck HG, De Nayer P, De Visscher M. Albumin, transferrin and the thyroxine-binding prealbumin/retinol-binding protein (TBPA-RBP) complex in assessment of malnutrition. Clin Chim Acta 1975; 63: 61-7.
9. Ogunshina SO, Hussaian MA. Plasma thyroxine binding prealbumin as an index of mild protein-energy malnutrition in Nigerian children. Am J Clin Nutr 1980; 33: 794-800.
10. Dao H, Dehsle H, Fournier P. Anthropometric status, serum prealbumin level and immune response 10 measles vaccination in Mali children. J Trop Pediatr 1992; 38: 179-84.
11. Wade S, Bleiberg-Daniel F, Le Moullac B, et al. Values of serum transthyretin measurements in the assessment of marginal protein-energy malnutrition in rats. J Nutr 1988; 118: 1002-10.
12. Ingenbleek Y, Van Den Schrieck HGP, De Nayer P, De Visscher M. The role of retinol-binding protein in protein-calorie malnutrition. Metabolism 1975; 24: 633-41.
13. Haider M, Haider SQ. Assessment of protein-calorie malnutrition. Clin Chem 1984; 30, 8: 1286-99.
14. Spiekerman AM. Proteins used in nutritional assessment. Clin Lab Med 1993; 13: 353-69.
15. Akira S, Taga T, Kishimoto T. Interleukin-6 in biology and medicine. Adv Immunol 1993; 54: 1-78.
16. Castel JV, Andus T, Junz D, Heinrich PC. Interleukin-6: the major regulator of acute-phase protein synthesis in man and rat. Ann NY Acad Sci 1989; 557: 87-101.
17. Méndez-Castellano H, de Méndez MC. Sociedad y estratificación. Método Graffar-Méndez Castellano. Ediciones Fundacredesa, Caracas, 1994.
18. López Blanco M, Landaeta Jiménez M. Manual de crecimiento y desarrollo. Sociedad Venezolana de Puericultura y Pediatría. Capítulo de Crecimiento, Desarrollo, Nutrición y Adolescencia. Caracas, Fundacredesa, Serono, 1991.
19. WHO Working Group. Use and interpretation of anthropometric indicators of nutritional status. Bull WHO 1986; 64: 929-41.
20. Jordan MD. Anthropometric software package, tutorial guide and handbook. Version 3.0 Centers for Disease Control, Atlanta, GA, 1987.
21. Keller W, Fillmore CM. Prevalence of protein-energy malnutrition. Wld Hlth Statist Quart 1983; 36: 129-40.
22. Pirela M, Análisis de mortalidad y predicción de riesgo de morir a partir de indicadores antropométricos en niños menores de 5 años de una población rural de Guatemala. Facultad de Ciencias Médicas, Universidad de San Carlos, Guatemala. Tesis de M.Sc. Publicación INCAP. T-441, 1988.
23. Henrique de Paredes G, López de Blanco ME, Hernández de Valera Y. Análisis antropométricos en la evaluación de la desnutrición aguda en pre-escolares. Arch Ven Puer Ped 1982; 45: 8-17.
24. Chen LC, Chowdhury, Huffman SL. Anthropometric assessment of energy-protein malnutrition and subsequent risk of mortality among preschool aged children. Am J Clin Nutr 1980; 33: 1836-45.
25. Mancini G, Carbonara AO, Heremans JF. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 1965; 2: 235-54.
26. Oppenheimer JH, Surks MI, Bernstein G, Smith JC. Metabolism of iodine-131 labelled thyroxine binding prealbumin m man. Science 1975; 149: 748-51
27. Morton AG, Tavill AS. The role of iron in the regulation of hepatic transferrin synthesis. Br J Haematol 1977; 36: 383-94
28. Taylor P, Martínez-Torres C, Méndez-Castellano H, et al. The relationship between iron deficiency and anemia in Venezuelan children. Am J Clin Nutr 1993; 58: 215-18.
29. Muhilal H, Glover J. Effects of dietary deficiencies of protein and retinol on the plasma level of retinol-binding protein in the rat Br J Nutr 1974; 32: 549-58.
30. Bernard A, Vyskocyl A, Mahieu P, Lauwerys R. Effect of renal insufficiency on the concentration of free retinol-binding protein in urine and serum. Clin Chim Acta 1988; 171: 85-94.
31. Schreiber G, Hewlett G, Nagashima M, et al. The acute phase response of plasma protein synthesis during experimental inflammation. J Biol Chem 1982; 257: 10271-7.
32. Felding P, Fex G. Rates of synthesis of prealbumm and retinol-binding protein during acute inflammation in the rat. Acta Physiol Scand 1985; 123: 477-83.
33. Birch HE, Schreiber G. Transcriptional regulation of plasma protein synthesis during inflammation. J Biol Chem 1986; 261: 18, 8077-80.
34. Banalena L, Farsetti A, Flinck IL, Robbins J. Effects of interleukin-6 in the expression of thyroid hormone-binding protein genes in cultured human hepatoblastoma-derived (Hep G2) cells. Mol Endocrinol 1992; 6: 935-42.
35. Vahlquist A, Peterson PA, Wibell L. Metabolism of the vitamin A transporting protein complex. I. Turnover studies in normal persons and in persons with chronic renal failure. Eur J Clin Invest 1973; 3: 352-62.
36. Ballou SP, Kushner I. C-reactive protein and the acute phase response. Adv Int Med 1992; 313-36.
37. Deitch EA, Ma WJ, Ma L, Berg RD, Specian RD. Protein malnutrition predisposes to inflammatory induced gutorigin septic states. Ann Surg 1990; 211: 560-7.
38. Bradley SF, Vibhagood A, Kunkel SL, Kauffman CA. Monokine secretion in aging and protein malnutrition. J Leuk Biol 1989; 510-14.
39. Malavé I, Correa C, Carvajal I, Rojas I, Castillo C, Pérez M. Interleukin-1 in undernourished children. Arch Ven Puer Pediat 1993; 56: 136-42.
40. Gelfand RA, Defranzo RA, Gusberg R. Metabolic alterations associated with major injury or infection. In: Kleinbergern G, Deutsch E (eds), New Aspects of Clinical Nutrition. Karger, Basel, 1983; 211-39.
41. Suskind R. Immune status of the malnourished host. J Trop Fed 1980; 26: 1-6
42. Alvarado J, Luthringer DG. Serum immunoglobulins in edematous protein-caloric malnourished children. Clin Pediatr 1971; 10: 174-7.
43. Watson CE, Freeseman D., Immunoglobulins in protein-caloric malnutrition. Arch Dis Child 1970; 45: 282-4
44. Malavé I, Pocino M. Polyclonal B-cell response to stimulation with Escherichia coli lipopolysaccharide in dietary protein restriction. Inf Immunol 1982; 38: 31-4.
45. Pocino M, Malavé I. Enhancement of the in vitro antibody response in dietary protein restriction. Failure in the regulation of antibody synthesis. Immunology 1981; 43: 235-40.
46. Greenberg AS, Nordan RP, McIntosh J, Calvo JC, Scow RO, Jablon D. Interleukin-6 reduced lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin-6 in cancer cachexia. Cancer Res 1992; 52: 4113-16.
47. Strassmann G, Fong M, Keney JS, Jacob CO. Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J Clin Invest 1992; 89: 1681-4.
48. Ohe Y, Podack ER, Olsen KJ, et al. Interleukin-6 transfected Lewis lung carcinoma cells show unaltered net tumor growth rate but cause weight loss and shorten survival in syngenic mice. Br J Cancer 1993; 67: 937-44.